Bi-Mix Injection

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All the Info

Here are the facts you should know.

Dosage Strengths

Papaverine HCl 30 mg/mL, Phentolamine Mesylate 1 mg/mL. 5 mL Vial.

Papaverine HCl 30 mg/mL, Phentolamine Mesylate 2 mg/mL. 5 mL Vial.

General Information

BiMix is administered as a penile self-injection, typically considered to be a powerful class of anti-erectile dysfunction agents. While the components of BiMix (Papaverine, Phentolamine) are, on their own, indicated for a vast number of different conditions, the practice of bringing them together in concert to treat erectile dysfunction has become commonplace in sexual medicine and is now considered the go-to treatment if a patient is not responsive to conventional PDE5 inhibitors. BiMix is used in the treatment of erectile dysfunction in males. BiMix contains two drugs from complimentary classes designed to act synergistically, mixed into a sterile injection. They are:

Suggested Directions

Ideally, the injection should be administered just prior to foreplay. It is administered via intracavernosal injection and should produce an erection in 5 to 20 minutes and can be expected to last up to one hour. To prevent bruising, apply firm pressure to the injection site for 5 minutes after injecting. Do not use BiMix Injection more than two times a week; use at least 24 hours apart. There is a possibility of needle breakage with use of BiMix Injection: you should pay careful attention to your doctor's instructions and handle syringe and needle properly.

Side Effects

Mild to moderate pain during injection; painful sensation with erection; small amount of bleeding at the injection site. Call your healthcare provider if you notice any redness, lumps, swelling, tenderness or curvature of the erect penis. If you experience an erection lasting more than 2 hours, you may take 2 - 4 pseudoephedrine 30 mg by mouth once and apply an ice pack. If your erection does not go away within the next hour, seek professional help immediately. Erections that last more than 6 hours can cause serious damage to penile tissue.

Storage

Store dry powder at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Once reconstituted keep this medicine in a refrigerator between 36°F to 46°F (2°C to 8°C). Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain.