Cleaning and Disinfection of Sterile Compounding Areas

This SOP establishes the requirements for cleaning and disinfecting sterile compounding areas—including daily, weekly, and monthly schedules for PECs, SECs, floors, walls, ceilings, shelving, sinks, and reusable garb; use of EPA-registered cleaning, disinfecting, and sporicidal agents; adherence to dwell times; final IPA residue removal; and documentation on cleaning logs—to ensure contamination control, environmental quality, and compliance with USP <797>.

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