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Trimix

  • Fast-acting and localized — works in minutes
  • Compounded to your provider's exact strength
  • Discreet, temperature-controlled shipping
How should Trimix be stored and used safely?

Trimix should usually be stored refrigerated unless the pharmacy label gives different instructions. Patients should follow the exact dose prescribed and should not adjust the dose without speaking with their prescriber. Trimix is injected using a small syringe, and patients should receive proper injection training before use. Seek urgent medical care for an erection lasting more than 4 hours, severe pain, significant swelling, or signs of infection.

What is Trimix and how does it work?

Trimix is a compounded injectable medication used to help treat erectile dysfunction. It typically contains three medications: alprostadil, papaverine, and phentolamine. These ingredients work together by relaxing smooth muscle and increasing blood flow into the penis, which may help produce an erection after injection. Trimix is customized by the prescriber and pharmacy based on the patient’s response, tolerability, and dosing instructions.

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Compounded medications are prepared pursuant to a valid prescription for an individual patient and are not FDA-approved. This page is for educational purposes and is not medical advice.
**The FDA does not review or approve compounded medications for safety or effectiveness. A valid prescription from a licensed practitioner is required.
Important safety information →

What is Trimix?

Trimix is a compounded injectable medication used to treat erectile dysfunction. It combines three vasodilator medications that work together to increase blood flow to the penis. Because it's custom-compounded, Trimix isn't an off-the-shelf product — it's prepared by a compounding pharmacy against a prescription and tailored to the strength your provider specifies.

What's in it

  • Alprostadil — relaxes smooth muscle and widens blood vessels in penile tissue.
  • Papaverine — a vasodilator that helps increase localized blood flow.
  • Phentolamine — supports blood flow by blocking vessel constriction.

Trimix is a prescription-only compounded medication and is not FDA-approved. Your provider determines whether it's appropriate and sets the formulation and dose.

Compounded to your exact dose

Your medication is personalized just for you, down to your exact dosage requirements outlined by your prescriber.

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Built for second-line treatment

When oral ED tablets aren't the right fit, Trimix is injected directly and works within minutes…

Get the most out of Trimix

Discreet delivery
Custom strengths
Localized action
Works in minutes

Frequently asked questions

How should Trimix be stored and used safely?

Trimix should usually be stored refrigerated unless the pharmacy label gives different instructions. Patients should follow the exact dose prescribed and should not adjust the dose without speaking with their prescriber. Trimix is injected using a small syringe, and patients should receive proper injection training before use. Seek urgent medical care for an erection lasting more than 4 hours, severe pain, significant swelling, or signs of infection.

What is Trimix and how does it work?

Trimix is a compounded injectable medication used to help treat erectile dysfunction. It typically contains three medications: alprostadil, papaverine, and phentolamine. These ingredients work together by relaxing smooth muscle and increasing blood flow into the penis, which may help produce an erection after injection. Trimix is customized by the prescriber and pharmacy based on the patient’s response, tolerability, and dosing instructions.