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Erectile Dysfunction occurs when a man cannot get or keep an erection firm enough for sexual intercourse. It can happen occasionally or frequently, and its severity can vary.
ED can be caused by a range of physical, emotional, and lifestyle factors, including:
Physical causes: Heart disease, diabetes, high blood pressure, high cholesterol, obesity, and certain medications.
Emotional causes: Stress, anxiety, depression, and relationship issues.
Lifestyle factors: Smoking, excessive alcohol consumption, lack of physical activity, and poor diet.
Understanding the underlying cause of ED is part of how a prescriber decides on treatment. Bayview Pharmacy works with your healthcare provider to compound what they prescribe.
Erectile dysfunction is managed differently from patient to patient. We compound a range of dosage forms so your prescriber can choose the route and strength that fits.
Oral PDE5 inhibitors are a commonly prescribed option for erectile dysfunction. We supply commercially available tablets and compound oral dissolve tablets and troches.
Our options include commercially available tablets, rapid dissolve tablets, and troches. PDE5 inhibitors act by increasing blood flow to the penis during sexual stimulation.
We offer two of the most widely recognized oral medications for ED in their commercially available tablet form:
Sildenafil is one of the most commonly prescribed medications for ED. It works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), which can restrict blood flow to the penis. By blocking this enzyme, Sildenafil helps the blood vessels in the penis relax. This allows more blood to flow in when you’re sexually aroused.
Typically, Sildenafil is taken 30 minutes to an hour before sexual activity, and its effects can last for up to 4 hours. It’s important to note that Sildenafil will only work if you are sexually stimulated—it doesn’t cause an erection on its own.
Tadalafil is often referred to as the “weekend pill” because of its longer duration of action. Its effects can last up to 36 hours. Like Sildenafil, Tadalafil works by inhibiting PDE5 and increasing blood flow to the penis. However, its extended half-life means that you don’t need to time your medication as precisely before sexual activity. This allows for more spontaneity.
Tadalafil can be taken as needed. In some cases, a lower daily dose is used instead. This is for those who prefer to be ready for sexual activity at any time without planning ahead.
Both are available in commercially manufactured tablet form.
Oral Dissolve Tablets (ODTs) offer a faster-acting alternative to traditional oral medications. These tablets are designed to dissolve quickly on your tongue, allowing the active ingredients to be absorbed into your bloodstream more rapidly. This can result in a quicker onset of action, making it easier to respond to spontaneous sexual activity.
Sildenafil in oral dissolve form contains the same active ingredient as the standard tablet, absorbed through the oral mucosa. Reported onset is typically 15 to 20 minutes, compared with 30 to 60 minutes for a swallowed tablet.
Tadalafil in rapid dissolve form combines tadalafil's extended duration with mucosal absorption.
Tadalafil has a duration of up to 36 hours; the rapid dissolve form shortens onset.
Vardenafil is a PDE5 inhibitor with a mechanism similar to sildenafil and tadalafil. In rapid dissolve form it is absorbed through the oral mucosa, with a reported onset of 15 to 30 minutes.
Oral dissolve tablets are absorbed through the oral mucosa, which shortens onset relative to swallowed tablets.
Troches offer a unique and versatile option for treating Erectile Dysfunction. These small, lozenge-like medications are designed to dissolve slowly in your mouth, typically between your cheek and gum. This allows the active ingredients to be absorbed directly through the mucous membranes.
This route provides a more gradual and sustained release than a swallowed tablet.
Sildenafil in troche form contains the same active ingredient as the tablet, released gradually through the buccal mucosa.
The troche dissolves slowly, providing a steady release of sildenafil.
Tadalafil troches release tadalafil gradually as the troche dissolves. Tadalafil has a duration of up to 36 hours.
Vardenafil in troche form is released gradually as the troche dissolves through the buccal mucosa.
Troches provide a slower, sustained release than immediate-release tablets.
At Bayview Pharmacy we compound injectable preparations for erectile dysfunction in our USP 797 sterile laboratory, under our documented quality program.
Injectable therapy is one route prescribers use for erectile dysfunction. Each formulation is compounded to the concentration your prescriber specifies; discuss risks and side effects with them.
Alprostadil is a single-agent injectable for erectile dysfunction. It acts locally to relax vascular smooth muscle in the penis, increasing blood flow during sexual arousal.
Alprostadil is one option a prescriber may select. It is administered by intracavernosal injection and dose-titrated by the practitioner.
Bi-Mix combines two active ingredients, papaverine and phentolamine. Papaverine relaxes smooth muscle and phentolamine causes vasodilation.
Bi-Mix is one of several injectable formulations a prescriber may select. Prescribers consider prior therapy and response when choosing a formulation.
Tri-Mix with Atropine combines three active ingredients: atropine, papaverine, and phentolamine. Atropine is an anticholinergic agent included to support smooth muscle relaxation. Your prescriber determines which formulation is appropriate.
Tri-Mix without Atropine includes three active ingredients: alprostadil, papaverine, and phentolamine. Your prescriber determines which formulation is appropriate.
Quad-Mix combines four active ingredients: alprostadil, atropine, papaverine, and phentolamine. It is prescribed at a practitioner's discretion.
Quad-Mix is prescribed and dose-titrated by a practitioner. Your prescriber determines whether it is appropriate.
At Bayview Pharmacy, we offer a variety of urethral gels specially compounded to treat Erectile Dysfunction (ED). These gels are designed for easy administration directly into the urethra, allowing the active ingredients to be absorbed locally.
Urethral administration provides local absorption and is one route a prescriber may choose. Each formulation is compounded to the prescribed concentration; discuss risks and side effects with your prescriber.
Bi-Mix Urethral Gel combines papaverine and phentolamine. Papaverine relaxes smooth muscle in the penis and phentolamine causes vasodilation.
The gel is administered urethrally and absorbed locally. Bi-Mix Gel is one of the urethral gel formulations we compound.
Tri-Mix Urethral Gel combines three active ingredients: alprostadil, papaverine, and phentolamine. Alprostadil is a vasodilator; papaverine and phentolamine act on smooth muscle and vasculature.
This formula combines three active ingredients rather than two. Your prescriber determines which formulation is appropriate.
High-Dose Triple P Urethral Gel contains higher concentrations of the same three active ingredients.
This formulation includes increased concentrations of alprostadil, papaverine, and phentolamine, as prescribed.
