Alprostadil 500 mcg/Papaverine 7.5 mg/Phentolamine 1 mg/ml Urethral Gel

Alprostadil 500 mcg/Papaverine 7.5 mg/Phentolamine 1 mg/ml Urethral Gel is a compounded medication used to treat erectile dysfunction, Peyronie's disease, and other urological conditions.

Alprostadil is a vasodilator that helps increase blood flow to the penis, Papaverine is a smooth muscle relaxant, and Phentolamine is an alpha-adrenergic blocker.

This compounded medication is administered directly into the urethra and is available in a gel form.

This formulation is also known as Tri-Mix Urethral Gel, Triple-P Urethral Gel, Triple P Urethral Gel, or PPP urethral gel.

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Urethral Gel
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Formula Information

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Bayview Pharmacy's Alprostadil 500 mcg/Papaverine 7.5 mg/Phentolamine 1 mg/ml Urethral Gel is a specialized formulation designed for application into the urethra. It is dispensed in syringes for precise and controlled administration, delivering medication or lubrication for targeted treatment of urethral conditions or facilitating certain medical procedures. This formulation ensures accurate placement and optimal efficacy for the treatment of various urethral diseases.

The Alprostadil 500 mcg/Papaverine 7.5 mg/Phentolamine 1 mg/ml Urethral Gel is used to treat a variety of urethral diseases, including urethritis, urinary tract infections, and prostatitis. It can also be used to facilitate certain medical procedures, such as urethral dilation and catheterization. The gel-like formulation is designed to provide lubrication and reduce discomfort during these procedures.

Bayview Pharmacy's Alprostadil 500 mcg/Papaverine 7.5 mg/Phentolamine 1 mg/ml Urethral Gel is an effective and safe treatment option for urethral diseases and medical procedures. If you have any questions about this formulation, please reach out to us.

Drug Interactions

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Alprostadil 500 mcg/Papaverine 7.5 mg/Phentolamine 1 mg/ml Urethral Gel is a gel-like formulation specifically designed for application into the urethra, dispensed in syringes for precise and controlled administration, delivering medication or lubrication for targeted treatment of urethral conditions or facilitating certain medical procedures, ensuring accurate placement and optimal efficacy. This formulation is indicated for the treatment of erectile dysfunction, Peyronie's disease, priapism, post-radical prostatectomy syndrome, and urethral stricture.

The combination of alprostadil, papaverine, and phentolamine in this formulation is thought to act synergistically to relax the smooth muscle of the corpus cavernosum, allowing for increased blood flow and improved erectile function. Alprostadil is a prostaglandin E1 analog that acts directly on the smooth muscle of the corpus cavernosum, while papaverine and phentolamine are non-selective phosphodiesterase inhibitors that act to increase the levels of cyclic guanosine monophosphate (cGMP) and nitric oxide (NO) in the corpus cavernosum.

The combination of alprostadil, papaverine, and phentolamine in this formulation has also been shown to be effective in the treatment of Peyronie's disease, priapism, post-radical prostatectomy syndrome, and urethral stricture. In the case of Peyronie's disease, the combination of these agents is thought to act to reduce the fibrous plaques that cause the curvature of the penis. In the case of priapism, the combination of these agents is thought to act to reduce the persistent erection by decreasing the levels of cGMP and NO in the corpus cavernosum. In the case of post-radical prostatectomy syndrome, the combination of these agents is thought to act to reduce the symptoms of erectile dysfunction by increasing the levels of cGMP and NO in the corpus cavernosum. Finally, in the case of urethral stricture, the combination of these agents is thought to act to reduce the narrowing of the urethra by relaxing the smooth muscle of the urethra.

It is important to note that this formulation should only be used as directed by a healthcare professional. Patients should be advised to use the medication as prescribed and to follow all instructions for proper administration. Patients should also be advised to seek medical attention if they experience any adverse effects or if their symptoms do not improve. If you have any questions about this formulation or its use, please reach out to us.

How Does it Work

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Alprostadil 500 mcg/Papaverine 7.5 mg/Phentolamine 1 mg/ml Urethral Gel is a gel-like formulation specifically designed for application into the urethra, dispensed in syringes for precise and controlled administration. This formulation is used to treat a variety of urethral conditions, including erectile dysfunction, Peyronie's disease, priapism, post-radical prostatectomy syndrome, and urethral stricture.

The gel is applied directly into the urethra, where it delivers medication or lubrication for targeted treatment of the condition. This ensures accurate placement and optimal efficacy. The gel is dispensed in syringes for precise and controlled administration, allowing for accurate dosing and delivery of the medication.

For patients with erectile dysfunction, the gel helps to relax the muscles in the penis, allowing for increased blood flow and improved erections. For patients with Peyronie's disease, the gel helps to reduce the curvature of the penis, allowing for improved sexual function. For patients with priapism, the gel helps to reduce the duration and severity of the condition. For patients with post-radical prostatectomy syndrome, the gel helps to reduce the symptoms associated with the condition. For patients with urethral stricture, the gel helps to reduce the narrowing of the urethra, allowing for improved urinary flow.

If you have any questions about this formulation or how it works, please reach out to us at Bayview Pharmacy. We are a knowledgeable team of compounding pharmacists and are here to help.

Other Uses

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Alprostadil 500 mcg/Papaverine 7.5 mg/Phentolamine 1 mg/ml Urethral Gel is a gel-like formulation specifically designed for application into the urethra, dispensed in syringes for precise and controlled administration, delivering medication or lubrication for targeted treatment of urethral conditions or facilitating certain medical procedures, ensuring accurate placement and optimal efficacy. This formulation can also be used for other purposes, such as:

• To reduce the risk of urinary tract infections (UTIs) in patients with recurrent UTIs. This formulation can be used to coat the urethra and provide a protective barrier against bacteria, reducing the risk of infection.

• To reduce the risk of sexually transmitted infections (STIs) in patients with recurrent STIs. This formulation can be used to coat the urethra and provide a protective barrier against bacteria, reducing the risk of infection.

• To reduce the risk of post-operative infection in patients undergoing urological procedures. This formulation can be used to coat the urethra and provide a protective barrier against bacteria, reducing the risk of infection.

• To reduce the risk of post-operative pain in patients undergoing urological procedures. This formulation can be used to coat the urethra and provide a lubricating effect, reducing the risk of pain.

• To reduce the risk of post-operative bleeding in patients undergoing urological procedures. This formulation can be used to coat the urethra and provide a protective barrier against bleeding, reducing the risk of bleeding.

If you have any questions about the other uses of Alprostadil 500 mcg/Papaverine 7.5 mg/Phentolamine 1 mg/ml Urethral Gel, please reach out to us.

Frequently Asked Questions

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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