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Formulas

Acetaminophen 325 mg/Promethazine HCl 20 mg Suppository

FDA-approved generic
Dose form
Suppository
Active ingredients
Acetaminophen
Promethazine Hydrochloride

The Acetaminophen 325 mg/Promethazine HCl 20 mg Suppository is a solid dosage form designed for insertion into a body cavity, typically the rectum or vagina. Upon dissolution or melting, it releases the medication for local or systemic absorption. This formulation is commonly used to alleviate pain, nausea, vomiting, allergic reactions, and motion sickness.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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No prescription yet?

Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Acetaminophen
Promethazine Hydrochloride
Suppository
6427079ea64324184e5185c0
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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Acetaminophen 325 mg/Promethazine HCl 20 mg Suppository is a compounded medication that combines two active ingredients, acetaminophen and promethazine hydrochloride, to treat a variety of conditions. This medication is a solid dosage form that is inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication for local or systemic absorption.

Acetaminophen is an analgesic and antipyretic that works to reduce pain and fever. Promethazine hydrochloride, on the other hand, is an antihistamine and sedative that helps to reduce inflammation and provide relief from itching and other symptoms. It can also be used to treat nausea, vomiting, and motion sickness.

It is crucial to follow the instructions provided by your healthcare provider when taking this medication. This medication should not be used in children under the age of two, as it can cause serious side effects. If you have any questions about this medication or its use, please consult with your healthcare provider.

Drug Interactions

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This compounded formulation of Acetaminophen 325 mg/Promethazine HCl 20 mg Suppository is designed for the treatment of symptoms such as nausea, vomiting, and pain associated with certain medical conditions. It is crucial to understand that this formulation is contraindicated in patients with a known hypersensitivity to either Acetaminophen or Promethazine HCl. Furthermore, it should not be administered to patients with a history of asthma, glaucoma, or urinary retention.

Patients are advised to abstain from alcohol while on this medication due to potential interactions. It is also important to note that this formulation may cause drowsiness, and patients should avoid operating heavy machinery or driving while on this medication. This formulation may also cause an increase in blood pressure and heart rate, so it should be used with caution in patients with hypertension or tachycardia.

There may be potential interactions with other medications, including anticholinergics, antihistamines, and monoamine oxidase inhibitors (MAOIs). Therefore, it is essential for patients to inform their healthcare provider of all medications they are currently taking before starting this formulation.

If you have any questions or concerns about this formulation, please do not hesitate to contact your healthcare provider or pharmacist for further information and guidance.

How Does it Work

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This compounded formulation of Acetaminophen 325 mg/Promethazine HCl 20 mg Suppository is a powerful combination of two medications designed to alleviate a range of symptoms. Acetaminophen, a well-known analgesic and antipyretic, functions by inhibiting the production of prostaglandins, substances in the body that contribute to pain and fever. Together, these two medications work synergistically to reduce pain, fever, and allergic reactions.

When using this formulation, it is crucial to follow the instructions provided by your healthcare provider. The suppository should be inserted into the rectum, ensuring it is inserted as far as possible for optimal absorption. It is important not to break or cut the suppository before insertion. Once inserted, the suppository should remain in place for at least 15 minutes before removal to ensure the medication has sufficient time to dissolve or melt and release the medication for local or systemic absorption.

It is important to note that this formulation is not recommended for use in children under the age of 2 years. Additionally, it is not advised for use in pregnant or breastfeeding women due to potential risks. If you have any questions or concerns about using this formulation, please do not hesitate to reach out to your healthcare provider or pharmacist for further guidance and advice.

Frequently Asked Questions

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What is the Acetaminophen 325 mg/Promethazine HCl 20 mg Suppository?

This is a compounded medication that combines Acetaminophen and Promethazine HCl in a suppository form. It is a solid dosage that is inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication for local or systemic absorption.

What is this medication used for?

Acetaminophen is used to relieve pain and reduce fever, while Promethazine HCl is used to treat allergies, motion sickness, nausea, and vomiting.

How should I use this medication?

This medication should be inserted into the rectum or vagina as directed by your healthcare provider. It is designed to dissolve or melt once inserted, releasing the medication for absorption.

What should I do if I miss a dose?

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

What are the potential side effects of this medication?

Common side effects may include drowsiness, dizziness, constipation, and dry mouth. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Can I take this medication if I am pregnant or breastfeeding?

Consult your healthcare provider before using this medication if you are pregnant or breastfeeding. The effects on the unborn baby or nursing infant are not fully known.

Can I drink alcohol while using this medication?

Alcohol may increase the risk of liver damage while using this medication. It is best to consult your healthcare provider before consuming alcohol while using this medication.

What should I do if I have an allergic reaction to this medication?

If you have an allergic reaction, such as hives, difficulty breathing, or swelling of your face, lips, tongue, or throat, seek medical attention immediately.

Can I drive or operate machinery after using this medication?

This medication may cause drowsiness or dizziness. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.

How should I store this medication?

Store this medication at room temperature, away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Acetaminophen 325 mg/Promethazine HCl 20 mg Suppository
Suppository
30 suppositories
controlled

Insert 1 unwrapped suppository

Every 6 hours as needed