Check out our most popular compounded medications! Get Started
Dashboard
Formulas

Acyclovir 2%/Amitriptyline HCl 2%/Ketoprofen 15%/Lidocaine HCl 2% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Acyclovir
Amitriptyline Hydrochloride
Ketoprofen
Lidocaine Hydrochloride

This formulation is a semisolid, gel-like compound containing Acyclovir 2%, Amitriptyline HCl 2%, Ketoprofen 15%, and Lidocaine HCl 2%. It is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The active ingredients are absorbed through the skin, providing targeted treatment for a variety of disease states.

Acyclovir is an antiviral medication used to treat Herpes Simplex Virus infections. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation associated with conditions such as osteoarthritis. Lidocaine HCl is a local anesthetic that provides temporary relief from pain and discomfort.

Together, these ingredients work synergistically to manage and alleviate symptoms associated with Herpes Simplex Virus infections, postherpetic neuralgia, neuropathic pain, osteoarthritis, and fibromyalgia.

View more
For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Get started as a patient
Get Started
This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Acyclovir
Amitriptyline Hydrochloride
Ketoprofen
Lidocaine Hydrochloride
Topical Gel
652f38fdebe233813a486551

Formula Information

A small arrow pointing down

This formulation is a compounded topical gel containing Acyclovir 2%, Amitriptyline HCl 2%, Ketoprofen 15%, and Lidocaine HCl 2%. It is designed to be dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the targeted area.

Acyclovir is an antiviral medication used to treat infections caused by the Herpes Simplex Virus. It works by slowing the growth and spread of the virus in the body. This helps to reduce the severity and duration of an outbreak of herpes. It is also used to reduce the risk of the virus spreading to other parts of the body and to other people.

Amitriptyline HCl is a tricyclic antidepressant that is used to treat various types of neuropathic pain, including postherpetic neuralgia, a painful condition that can occur after having shingles. It works by increasing the levels of certain chemicals in the brain that help elevate the mood and reduce the sensation of pain.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, swelling, and joint stiffness caused by arthritis, and other conditions such as fibromyalgia. It works by reducing the production of certain substances in the body that cause inflammation and pain.

Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is used to relieve pain and discomfort caused by skin irritations and conditions such as sunburn, insect bites, poison ivy, and minor cuts, scratches, or burns.

This compounded formulation is designed to provide targeted relief from pain and discomfort associated with Herpes Simplex Virus infections, postherpetic neuralgia, neuropathic pain, osteoarthritis, and fibromyalgia. It is applied topically to the affected area, which allows for direct application and absorption of the active ingredients, reducing the potential for systemic side effects.

As with any medication, it is important to use this formulation as directed by your healthcare provider. If you have any questions or concerns about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to assist you.

Drug Interactions

A small arrow pointing down

The formulation contains Acyclovir, Amitriptyline HCl, Ketoprofen, and Lidocaine HCl. Each of these active ingredients has its own mechanism of action and potential for drug interactions. It's important to consider these interactions when prescribing or using this medication.

Acyclovir is an antiviral medication used to treat infections caused by the herpes simplex virus. It works by slowing the growth and spread of the virus in the body. Acyclovir may interact with probenecid, which can affect the removal of acyclovir from the body, leading to increased side effects. It may also interact with medications that can harm the kidneys (including nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen, naproxen).

Amitriptyline HCl is a tricyclic antidepressant used to treat neuropathic pain and fibromyalgia. It works by increasing the levels of certain chemicals in the brain that help elevate mood. Amitriptyline may interact with MAO inhibitors, SSRIs, anticholinergics, and certain antihypertensives. These interactions can lead to serious side effects such as serotonin syndrome, increased heart rate, and elevated blood pressure.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with conditions like osteoarthritis. It works by reducing the production of prostaglandins, chemicals that cause inflammation, pain, and fever in the body. Ketoprofen may interact with anticoagulants, antiplatelet drugs, corticosteroids, and other NSAIDs, increasing the risk of bleeding and stomach ulcers.

Lidocaine HCl is a local anesthetic used to relieve pain and discomfort caused by skin irritations. It works by blocking nerve signals in the body. Lidocaine may interact with antiarrhythmic drugs, beta-blockers, and cimetidine, which can affect how lidocaine is metabolized in the body and increase the risk of serious side effects.

It's important to inform your healthcare provider about all the medications you're currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions. Also, inform your healthcare provider if you have any kidney or liver disease, as these conditions can affect how these medications are metabolized and removed from your body.

This formulation is designed for topical application, which can reduce the risk of systemic side effects and drug interactions. However, systemic absorption can still occur, especially when applied over large skin areas or for prolonged periods. Therefore, it's important to use this medication as directed by your healthcare provider.

This medication is used to treat a variety of conditions, including herpes simplex virus infections, postherpetic neuralgia, neuropathic pain, osteoarthritis, and fibromyalgia. It works by targeting the underlying causes of these conditions, providing relief from symptoms and improving quality of life.

If you have any questions about this medication or its potential interactions, please reach out to us. We're here to help and provide the information you need to use this medication safely and effectively.

How Does it Work

A small arrow pointing down

This unique formulation combines four active ingredients: Acyclovir, Amitriptyline HCl, Ketoprofen, and Lidocaine HCl, each with a specific role in managing the symptoms of Herpes Simplex Virus Infections, Postherpetic Neuralgia, Neuropathic Pain, Osteoarthritis, and Fibromyalgia.

Acyclovir is an antiviral medication that works by slowing the growth and spread of the herpes virus in the body. It does not cure herpes, but it can lessen the symptoms of the infection. Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chickenpox.

Amitriptyline HCl is a tricyclic antidepressant that is widely used in the management of neuropathic pain. It works by increasing the levels of certain chemicals in the brain that help elevate the mood and reduce the sensation of pain. In this formulation, it is used to manage the pain associated with postherpetic neuralgia and fibromyalgia.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Ketoprofen is used to treat pain or inflammation caused by arthritis. It provides relief from symptoms of osteoarthritis, including inflammation, swelling, stiffness, and joint pain.

Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is used on the skin to stop itching and pain from certain skin conditions (e.g., scrapes, minor burns, eczema, insect bites) and to treat minor discomfort and itching caused by hemorrhoids and certain other problems of the genital/anal area.

This formulation is dispensed as a semisolid gel through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

It is important to note that while this formulation can help manage the symptoms of these conditions, it is not a cure. It should be used as part of a comprehensive treatment plan, under the supervision of a healthcare provider.

If you have any questions about this formulation, or if you would like more information, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

A small arrow pointing down

This compounded formulation of Acyclovir, Amitriptyline HCl, Ketoprofen, and Lidocaine HCl is typically employed in the therapeutic management of Herpes Simplex Virus Infections, Postherpetic Neuralgia, Neuropathic Pain, Osteoarthritis, and Fibromyalgia. However, it's versatile composition lends itself to several other potential uses.

Beyond its antiviral properties, Acyclovir is known to exhibit anti-inflammatory effects which may be beneficial in managing conditions involving inflammation. This could extend its use beyond herpes infection to conditions like eczema or psoriasis.

Amitriptyline is primarily known as an antidepressant, but it's also recognized for its effects in relieving chronic pain, particularly of neuropathic origin. Therefore, it could potentially be utilized off-label for conditions such as diabetic peripheral neuropathy pain or migraines with your doctor's discretion and supervision.

Ketoprofen, as a NSAID, offers strong analgesic, antipyretic and anti-inflammatory properties and could be applied to a host of conditions ranging from minor sprains and muscle inflammation to relieving pain and inflammation associated with rheumatoid conditions.

Lastly, Lidocaine, a local anaesthetic is commonly used to numb the tissue in a specific area. It may also be employed to relieve pain and discomfort from conditions such as burns, insect bites, or other skin conditions.

Overall, this formulation offers a unique combination that provides not only antiviral protection but also anti-inflammatory, analgesic, and anesthetic properties. This makes it an adaptable treatment option for other ailments involving pain, inflammation, or irritation. It is essential, however, that this formulation be employed under the guidance of a healthcare professional, as every individual's condition and medication tolerance varies. Off-label usage should be explored only under appropriate medical guidance and always considering an individual's particular symptomatology and medical history.

If you have further questions about this formulation, or if you would like to explore its potential in treating conditions other than those previously mentioned, be sure to reach out to us. As experienced compounding pharmacists, we're happy to provide the information and support you need to make well-informed decisions about your treatment options.

Frequently Asked Questions

A small arrow pointing down

What is Acyclovir 2%/Amitriptyline HCl 2%/Ketoprofen 15%/Lidocaine HCl 2% Topical Gel?

This is a compounded formulation of several medications which are dispensed in a gel form through a pump mechanism for precise application on the skin. The medication is used for targeted treatment with the active ingredients being absorbed directly through the skin.

How should I apply this compounded formulation?

This gel should be applied to the targeted area of the skin as directed by your healthcare provider.

Can this formulation be used for any skin condition?

No, this particular formulation is designed for specific conditions as determined by a healthcare professional. Always consult a healthcare provider before using this or any medications.

Is it safe to apply more than the instructed dose if symptoms persist?

No, it is always important to strictly follow the dosage prescribed by your healthcare provider to avoid potential overuse or adverse reactions.

What do I do if I miss a dose?

If you miss a dose, take it as soon as you can unless it's close to the time for your next dose. In this scenario, skip the missed dose and resume your regular dosing schedule. It's not advisable to double dose.

What are the side effects of using this formulation?

This medication may cause some side effects such as a skin rash, itching, redness, and irritation at the site of application. If these side effects persist or worsen, consult your healthcare provider immediately.

Do I need a prescription for this medication?

Yes, this medication is a compounded medication which means it is custom-made for you based on a prescription from your healthcare provider.

What should I do in case of contact with eyes or mouth?

If this compound comes into contact with your eyes or mouth, immediately wash the area with plenty of water and seek medical attention if any irritation persists.

Can I use this topical gel on open wounds?

No, you should not use this compound on open wounds or broken skin unless specifically instructed by your healthcare provider. It is meant for external use only.

How should I store the acyclovir, amitriptyline, ketoprofen and lidocaine gel?

The gel should be stored at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Acyclovir 2%/Amitriptyline HCl 2%/Ketoprofen 15%/Lidocaine HCl 2% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)