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Formulas

Acyclovir 2%/Levofloxacin 1%/Metronidazole 1%/Mupirocin 2% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Acyclovir
Levofloxacin Hydrochloride
Metronidazole
Mupirocin Calcium

This formulation is a combination of Acyclovir 2%, Levofloxacin 1%, Metronidazole 1%, and Mupirocin 2% in a topical gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

Acyclovir is an antiviral medication used to treat infections caused by certain types of viruses. Levofloxacin is an antibiotic that fights bacteria in the body. Metronidazole is an antibiotic and antiprotozoal medication used to treat various infections caused by anaerobic bacteria and certain parasites. Mupirocin is an antibiotic that prevents bacteria from growing on your skin.

This combination of medications is used to treat a variety of disease states, including but not limited to, skin infections, wound infections, herpes simplex infections, and bacterial infections. The unique blend of ingredients works together to combat these conditions, providing relief and promoting healing.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Acyclovir
Levofloxacin Hydrochloride
Metronidazole
Mupirocin Calcium
Topical Gel
652f5a9ed62665dab5a8ca59
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation is a combination of four active ingredients: Acyclovir 2%, Levofloxacin 1%, Metronidazole 1%, and Mupirocin 2%. Each of these ingredients plays a crucial role in treating various disease states. The formulation is designed as a semisolid gel, which is dispensed through a pump mechanism for easy and precise application on the skin.

Acyclovir is an antiviral medication used primarily to treat herpes simplex virus infections, including cold sores and genital herpes. It works by slowing the growth and spread of the herpes virus in the body. It is commonly used to treat skin infections, sinusitis, and urinary tract infections.

Metronidazole is an antibiotic and antiprotozoal medication. It is used to treat various infections, including those caused by bacteria and parasites. It works by killing bacteria and parasites that cause infections in your body. Mupirocin is a topical antibiotic that prevents bacteria from growing on your skin. It is used to treat skin infections such as impetigo.

The gel-like consistency allows for targeted treatment, ensuring that the medication is applied precisely where it is needed. The pump mechanism facilitates easy application and helps to prevent waste, making the treatment more cost-effective.

It is important to use this medication exactly as prescribed by your healthcare provider. Do not use more or less of it or use it more often than prescribed by your doctor. If you have any questions about this medication or its use, please do not hesitate to reach out to us. We are here to help and provide you with the information you need to ensure the safe and appropriate use of your medication.

Drug Interactions

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This formulation combines four active ingredients: Acyclovir, Levofloxacin, Metronidazole, and Mupirocin. Each of these medications has its own potential for drug interactions, which can be amplified when used in combination. It's important to inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs and supplements, to avoid potential interactions.

Acyclovir is an antiviral medication used to treat infections caused by certain types of viruses. It can interact with drugs such as Probenecid and Tenofovir, potentially affecting kidney function. It's also important to stay well hydrated while using this medication to prevent kidney stones.

Levofloxacin is a type of antibiotic known as a fluoroquinolone, used to treat bacterial infections. It can interact with drugs such as antacids, multivitamins, and other products containing calcium, magnesium, aluminum, or iron, which can bind with levofloxacin and prevent its absorption. It can also interact with antiarrhythmic drugs, increasing the risk of QT prolongation, a serious heart condition.

Metronidazole is an antibiotic and antiprotozoal medication used to treat various infections caused by anaerobic bacteria and certain parasites. It can interact with alcohol, leading to a disulfiram-like reaction with symptoms such as flushing, headache, nausea, and vomiting. It can also interact with blood thinners like warfarin, increasing the risk of bleeding.

Mupirocin is a topical antibiotic used to treat skin infections. As a topical medication, it has fewer systemic interactions, but it can cause skin irritation and allergic reactions in some people. It should not be used with other topical medications without consulting a healthcare provider.

This formulation is designed to provide targeted treatment for skin infections, combining the antiviral properties of acyclovir, the broad-spectrum antibacterial properties of levofloxacin and metronidazole, and the topical antibacterial properties of mupirocin. It's important to use this medication as directed by your healthcare provider and to complete the full course of treatment, even if symptoms improve earlier, to prevent the development of drug-resistant bacteria.

If you have any questions about this formulation or potential drug interactions, please don't hesitate to reach out to us.

How Does it Work

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This unique formulation combines four active ingredients: Acyclovir, Levofloxacin, Metronidazole, and Mupirocin, each with its own mechanism of action to treat a variety of skin conditions.

Acyclovir is an antiviral medication that works by slowing the growth and spread of the herpes virus in the body. It interferes with the virus's ability to replicate and infect new cells, thus helping to control the infection and allowing the body's immune system to combat the virus more effectively. It is commonly used to treat herpes simplex infections, including cold sores and genital herpes.

Levofloxacin is a fluoroquinolone antibiotic that works by stopping the growth of bacteria. It does this by inhibiting the enzymes that bacteria need to replicate, repair their DNA, and to transcribe and translate their genetic material. Levofloxacin is often used to treat a variety of bacterial skin infections.

Metronidazole is an antibiotic and antiprotozoal medication. It works by inhibiting the nucleic acid synthesis by disrupting the DNA of microbial cells. This leads to death of the bacteria or protozoa, treating infections caused by these organisms. Metronidazole is commonly used to treat rosacea, a skin condition that causes redness and pimples on the face.

Mupirocin is another antibiotic that works by stopping the growth of certain bacteria (Staphylococcus aureus and Streptococcus pyogenes) on the skin. It does this by blocking the protein synthesis of these bacteria, preventing them from growing and multiplying, thus treating the infection.

The gel formulation allows for easy and precise application on the skin, ensuring that the active ingredients are delivered directly to the affected area. This targeted treatment helps to maximize the effectiveness of the medication while minimizing potential side effects.

Always follow the prescribed dosage and application instructions to ensure the best possible outcome.

If you have any questions about this formulation or how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This multi-antibiotic topical formulation, composed of Acyclovir, Levofloxacin, Metronidazole, and Mupirocin, is traditionally used to manage and treat various topical infections due to its broad-spectrum antibacterial and antiviral properties. Acyclovir mainly functions as an antiviral drug effective against herpes simplex viruses. Levofloxacin is a strong broad-spectrum antibiotic with high efficiency against both gram-positive and gram-negative bacteria.

Other than these common uses, this particular formulation could potentially be beneficial in several other conditions. For example, due to the presence of Acyclovir, it could be used off-label as a preventive measure or early stage treatment for superficial skin infections caused by Varicella zoster virus (which causes chickenpox and shingles). Meanwhile, the combined antibacterial power of Levofloxacin, Metronidazole, and Mupirocin may make this gel an appropriate choice for external wound care, such as pressure sores or ulcers, and possibly certain veterinary applications.

However, it is essential to note that this topical gel should not be used in the eye, mouth, or other mucous membranes due to potential irritation or adverse reactions. Patients should also be aware of potential allergic reactions or other side effects related to each active ingredient. It should be used with caution in individuals with compromised renal function and pregnant or breastfeeding women.

Moreover, as resistance to antibiotics is a significant public health concern, this formulation must be used judiciously and only with a prescription, ensuring the appropriateness of therapy for each patient's specific need. Regular follow-up with the healthcare provider to monitor the treatment's progress and make necessary adjustments is equally crucial.

If you have any questions about the use of this formulation for other conditions not listed here, or need to learn about potential side effects or precautions, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is ready to assist and provide the necessary expertise.

Frequently Asked Questions

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What is this Acyclovir 2%/Levofloxacin 1%/Metronidazole 1%/Mupirocin 2% Topical Gel intended for?

This compound formulation is designed for external use on the skin to target specific conditions, such as bacterial infections, inflammation, and certain skin disorders.

Can I use this product for conditions other than skin diseases?

No, this topical gel is specifically designed for skin conditions. It's advisable to only use this product for the indication prescribed.

How do I apply Acyclovir 2%/Levofloxacin 1%/Metronidazole 1%/Mupirocin 2% Topical Gel?

The gel is dispensed through a pump mechanism and can be applied directly to the affected area of the skin. Make sure your skin is clean before application.

Does this topical gel have a specific application consistency?

Yes, the gel is a semisolid formulation designed for easy and precise application on the skin with a gel-like consistency.

How often should I apply this topical gel?

The frequency of application depends on your doctor's prescription. It's crucial to follow the prescribed usage to maximize the benefits.

What precautions should I take when using this medication?

Always use as directed by your healthcare provider. Avoid contact with the eyes, mouth, or nose, and wash your hands before and after application.

What are the active ingredients in this topical gel?

The active ingredients are Acyclovir, Levofloxacin, Metronidazole, and Mupirocin. They work together to treat certain types of bacterial infections and skin conditions.

Are there any known side effects of this medication?

As with all medications, side effects can occur although not everybody experiences them. If you notice any adverse reactions or changes in your condition, contact your healthcare provider immediately.

Can I use this topical gel with other skin products?

You should discuss with your healthcare provider. As this product contains multiple active ingredients, the use of other skin products may alter its function or increase the risk of side-effects.

What if I miss applying a dose?

If you miss a dose, apply it as soon as you remember. If it's close to the time for the next one, skip the missed dose and go back to your regular schedule. Do not use double the amount to make up for the missed one.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Acyclovir 2%/Levofloxacin 1%/Metronidazole 1%/Mupirocin 2% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Twice daily