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Acyclovir 2%/Urea 5% Topical Ointment

FDA-approved generic
Dose form
Topical Ointment
Active ingredients
Acyclovir
Urea

The Acyclovir 2%/Urea 5% Topical Ointment is a semi-solid formulation dispensed in a tube, specifically designed for external application to the skin. This ointment provides a greasy or oily base that aids in the delivery of the active ingredients, Acyclovir and Urea, for localized treatment. Acyclovir is an antiviral medication used to treat infections caused by certain types of viruses, while Urea is used to treat dry/rough skin conditions. This formulation is typically used for conditions such as skin inflammation, infections, or wound healing.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Acyclovir
Urea
Topical Ointment
65303d445675384a9a3a7937

Formula Information

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This formulation combines Acyclovir, an antiviral medication, and Urea, a keratolytic (skin-softening) agent, in a topical ointment designed for direct application to the skin. The ointment is a semi-solid formulation dispensed in a tube, providing a greasy or oily base that aids in the delivery of the medication to the affected area. This formulation is typically used for localized treatment of skin conditions such as inflammation, infections, or wound healing.

Acyclovir works by slowing the growth and spread of the herpes virus in the body. It is used to treat infections caused by certain types of viruses, including herpes simplex, which can cause cold sores on the face and genital herpes. It does not cure herpes, but it can lessen the symptoms of the infection. Acyclovir is also used to treat outbreaks of herpes simplex lesions in people with frequent outbreaks.

Urea is a substance that is naturally found in the skin, which is called a 'humectant'. It is used to help rehydrate dry, rough and scaly skin conditions. It works by increasing the amount of moisture in the skin by softening and breaking apart the dead skin cells on the skin's surface, helping the skin to shed dead cells from its top layer and slow down the process of skin cell turnover. This can help improve the appearance and texture of the skin, promote wound healing, and make other skin medications work better.

Together, Acyclovir and Urea in this formulation work synergistically to treat skin conditions. The Urea softens and exfoliates the skin, allowing the Acyclovir to penetrate more effectively and combat the viral infection. This formulation is typically applied to the affected area as directed by a healthcare provider, usually 2 to 5 times a day. It is important to use this medication regularly to get the most benefit from it.

As with any medication, there may be side effects such as mild pain or stinging when the medication is applied. If these effects persist or worsen, or if the condition does not improve after a few days, it is important to contact a healthcare provider. It is also important to inform the healthcare provider of any other medications being used, as there may be potential interactions.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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Acyclovir is an antiviral medication used to treat infections caused by certain types of viruses, such as herpes simplex and varicella-zoster. It works by slowing the growth and spread of the virus in the body. Urea is a keratolytic agent that helps to soften and remove dead skin cells, promoting the penetration of acyclovir into the skin.

While this topical formulation is generally safe and well-tolerated, it's important to be aware of potential drug interactions. Acyclovir may interact with other medications, including probenecid, which can affect acyclovir's removal from the body, potentially leading to side effects. If you're taking probenecid or any other medications, please inform your healthcare provider.

Urea, on the other hand, is unlikely to interact with other medications due to its topical application. However, it may cause skin irritation when used with other topical products that can cause dryness or irritation, such as medicated or abrasive soaps and cleansers, soaps and cosmetics with a strong drying effect, and products with high alcohol content. It's recommended to check with your healthcare provider before using other topical products while using this formulation.

It's also important to note that this formulation should not be used on broken or infected skin unless directed by a healthcare provider, as it may lead to increased absorption of the medication and potential systemic side effects. Avoid contact with the eyes, nose, mouth, and other mucous membranes. If contact occurs, rinse thoroughly with water.

As with any medication, it's crucial to use this formulation as directed by your healthcare provider. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Doing so may increase the chance of side effects.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

How Does it Work

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The Acyclovir 2%/Urea 5% Topical Ointment is a semi-solid formulation that is designed for external application to the skin. It is dispensed in a tube and provides a greasy or oily base that aids in the delivery of medication or therapeutic agents for localized treatment. This formulation is typically used for conditions such as skin inflammation, infections, or wound healing.

Acyclovir, the primary active ingredient in this formulation, is an antiviral medication. It works by slowing the growth and spread of the herpes virus in the body. Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chickenpox. It does not cure herpes, but it can lessen the symptoms of the infection.

Urea, the secondary active ingredient, is a substance that is naturally found in the skin, which is known as a 'humectant'. It works by increasing the capacity of the skin to absorb more water, thereby increasing its hydration. In higher concentrations, such as the 5% found in this formulation, urea also acts as a keratolytic agent. This means it helps to break down hard and scaly skin, making it softer and smoother. This can be particularly beneficial in conditions where the skin has become hard or thickened, such as in psoriasis or eczema.

When applied to the skin, the Acyclovir 2%/Urea 5% Topical Ointment works by delivering the active ingredients directly to the area of concern. The greasy or oily base of the ointment helps to ensure that the medication stays in place, providing a localized treatment that targets the specific area of skin inflammation or infection. This can help to reduce symptoms and speed up the healing process.

It's important to note that while this formulation can help to manage symptoms and speed up healing, it is not a cure for herpes or other viral infections. It should be used as part of a comprehensive treatment plan, under the guidance of a healthcare professional.

If you have any questions about the Acyclovir 2%/Urea 5% Topical Ointment, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

Other Uses

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Acyclovir is a potent antiviral medication often used to manage viral infections such as herpes simplex, chickenpox, and shingles. In this formulation, it is combined with urea, a substance known for its keratolytic properties. Together, they may be used to manage a range of skin conditions aside from the previously mentioned infections.

For instance, their combined effects can be used to enhance wound healing. Acyclovir intervenes in viral replication which may lead to rapid resolution and healing of virally-infected wounds. Meanwhile, Urea promotes hydration and exfoliation, helping to facilitate removal of dead tissue, thereby accelerating the general process of wound healing. The combination can also be used in the management of cold sores, given their propensity for viral infections. In cases of eczema, the urea component assists in rehydrating the skin and keeping it moisturized, offering relief from dryness and itchiness.

Additionally, the formulation may be used off-label for other conditions such as molluscum contagiosum, a highly contagious viral infection of the skin. Also the combined formulation is capable of managing conditions like seborrheic keratosis, a benign skin growth, by using the urea’s keratolytic effect helping in the sloughing off and gradual breakdown of growth.

Note that off-label use should only be considered under the guidance and close supervision of a healthcare provider given the potential side effects of Acyclovir which include local irritation, burning, itching, and inflammation, and systemic side effects seen with oral administration of the drug.

This is a broad overview of the potential other uses of Acyclovir 2%/Urea 5% Topical Ointment and may not cover all possible scenarios or disease states. The specific application and benefits of the product may vary depending on the unique situation of the patient. Always consult your healthcare provider or a compounding pharmacist for advice. If you have additional questions about this formulation, kindly reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is Acyclovir 2%/Urea 5% Topical Ointment?

Acyclovir 2%/Urea 5% Topical Ointment is a compounded medication that contains acyclovir and urea. It is applied to the skin to treat certain conditions. The ointment has a semi-solid formulation and is designed for external application.

What are the active ingredients in this ointment?

The active ingredients in this ointment are Acyclovir and Urea. Acyclovir is an antiviral medication, while urea is used to heal damaged skin.

How is Acyclovir 2%/Urea 5% Topical Ointment used?

The ointment is dispensed in a tube and is designed for external application to the skin. It should be applied as directed by a healthcare professional.

What conditions is this ointment typically used to treat?

Acyclovir 2%/Urea 5% Topical Ointment is typically used to treat skin inflammation, infections, and for wound healing.

Does the ointment have a greasy or oily texture?

Yes, the ointment provides a greasy or oily base, which aids in the delivery of the medication or therapeutic agents for localized treatment.

Is this ointment dispensed in a tube?

Yes, the Acyclovir 2%/Urea 5% Topical Ointment is dispensed in a tube for easy application.

Can I use this ointment for other skin conditions not mentioned?

No, Acyclovir 2%/Urea 5% Topical Ointment should only be used for the conditions indicated and as directed by your healthcare provider. Using it for other conditions may be ineffective or harmful.

Can I use the ointment on open wounds?

The ointment can help in wound healing, but you should consult your healthcare provider before using it on open or large wounds.

Can I use the ointment if I am allergic to Acyclovir or Urea?

No, If you are allergic to Acyclovir or Urea, you should not use this ointment. An allergic reaction could lead to serious side effects.

What are the side effects of using Acyclovir 2%/Urea 5% Topical Ointment?

The side effects can vary between individuals. Common side effects can include irritation or redness at the site of application. If you experience any severe side effects, you should discontinue use and consult your healthcare provider immediately.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Acyclovir 2%/Urea 5% Topical Ointment
Topical Ointment
30 g
controlled

Apply topically to affected area(s)