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Acyclovir 5%/Hydrocortisone 2% Topical Cream

Acyclovir 5%/Hydrocortisone 2% Topical Cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This formulation is specifically designed for localized treatment or absorption of active ingredients. The cream contains Acyclovir, an antiviral medication, and Hydrocortisone, a corticosteroid, which work together to treat a variety of skin conditions.

The combination of these two active ingredients in a single formulation provides a comprehensive treatment approach for these disease states.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.

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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Acyclovir
Hydrocortisone
Topical Cream
652f204e4d24cbbb769a5172

Formula Information

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This formulation combines Acyclovir, an antiviral medication, and Hydrocortisone, a corticosteroid, into a 5%/2% topical cream. The cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This allows for localized treatment or absorption of the active ingredients, providing targeted relief for specific areas of the skin.

Acyclovir works by slowing the growth and spread of the herpes virus in the body. It is used to treat infections caused by certain types of viruses, including herpes simplex, which can cause cold sores on the face and genital herpes. However, it does not cure herpes, but it can decrease the symptoms of the infection. Acyclovir is also used to treat outbreaks of herpes simplex on the skin (mouth, lips, and genitals), and to help reduce the number of future episodes.

Hydrocortisone, on the other hand, is a corticosteroid that reduces redness, itching, and swelling. It is commonly used to treat a variety of skin conditions including eczema, dermatitis, allergies, and rash. Hydrocortisone works by decreasing your body's immune response to these conditions, thereby reducing symptoms such as swelling, itching, and redness.

Together, Acyclovir and Hydrocortisone in this topical cream formulation provide a dual-action treatment for skin conditions. The Acyclovir targets the viral infection, while the Hydrocortisone reduces the associated inflammation and discomfort. This makes it a versatile treatment option for conditions such as cold sores and genital herpes, where both a viral infection and inflammatory response are present.

It's important to note that this medication should be used as directed by a healthcare professional. The cream should be applied to the affected area and rubbed in gently until it is fully absorbed. Avoid contact with the eyes and mouth, and wash your hands before and after applying the cream. If your symptoms do not improve or if they worsen, contact your healthcare provider.

If you have any questions about this formulation, or if you would like more information on how it can be used to treat specific conditions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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Acyclovir 5%/Hydrocortisone 2% Topical Cream is a combination medication used to treat certain types of skin infections. Acyclovir is an antiviral drug that stops the growth of certain viruses, while hydrocortisone is a corticosteroid that reduces redness, itching, and inflammation.

Drug interactions can change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: other corticosteroids (such as prednisone), other antiviral medications (such as valacyclovir), and drugs that suppress the immune system (such as cyclosporine). If you are currently taking any of these medications, let your doctor or pharmacist know before starting Acyclovir/Hydrocortisone Topical Cream.

It's also important to note that this medication may interfere with certain laboratory tests (including certain urine protein tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

While using this medication, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval. If you are pregnant, planning to become pregnant, or are breastfeeding, talk to your doctor before using this medication. This medication should only be used when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. If you have any questions or concerns about this medication, please reach out to us at Bayview Pharmacy. We are here to help.

How Does it Work

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Acyclovir 5%/Hydrocortisone 2% Topical Cream is a combination medication that works by utilizing the therapeutic properties of both Acyclovir and Hydrocortisone. This formulation is designed to be applied topically, directly onto the skin, and is dispensed via a pump mechanism for easy and controlled application.

Acyclovir, an antiviral medication, works by slowing the growth and spread of the herpes virus in the body. It interferes with the virus's ability to replicate and infect new cells, thereby controlling the infection and allowing the body's immune system to overcome it. However, it's important to note that while Acyclovir can control a herpes outbreak, it does not cure the infection or prevent the transmission of the disease to others.

Hydrocortisone, on the other hand, is a corticosteroid that works by reducing inflammation and immune responses. When applied to the skin, it can help to reduce redness, itching, and swelling caused by certain skin conditions. This can provide significant relief from symptoms and improve the overall condition of the skin.

Together, these two active ingredients work synergistically to manage conditions such as herpes simplex virus infections. The Acyclovir component helps to control the viral infection, while the Hydrocortisone component helps to manage the associated inflammation and discomfort.

It's important to use this medication exactly as directed by your healthcare provider. The cream should be applied to the affected area and rubbed in gently until it is fully absorbed. Avoid contact with the eyes and mouth, and wash your hands thoroughly after application. If your symptoms do not improve or if they worsen, contact your healthcare provider.

As with any medication, Acyclovir 5%/Hydrocortisone 2% Topical Cream may cause side effects. Common side effects may include mild skin irritation, burning, or itching at the application site. If these side effects persist or worsen, or if you experience any serious side effects such as skin discoloration or thinning, contact your healthcare provider immediately.

If you have any questions about this medication, its use, or its potential side effects, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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While the primary use of Acyclovir 5%/Hydrocortisone 2% Topical Cream is for the treatment of herpes simplex labialis (cold sores), it may also be used for other virus-related skin conditions. The virus causing these conditions infects skin cells, causing inflammation and discomfort. The acyclovir component aids in halting the replication of viral cells, reducing the course of the condition.

Additionally, Acyclovir 5%/Hydrocortisone 2% Topical Cream may also manage some symptoms of eczema herpeticum and keratitis. Eczema herpeticum is a rare complication of atopic dermatitis and is characterized by disseminated herpes simplex. On the other hand, keratitis is a viral eye infection, and topical usage can potentially reduce corneal scarring and improve ocular outcomes, though typically used as an adjunctive treatment rather than a primary one.

The secondary component of this compounded cream, hydrocortisone, supplies anti-inflammatory and immune-suppressing properties, reducing redness, swelling, and itching associated with these conditions. It should be noted, however, that the use of this medication for conditions beyond herpes simplex labialis should be under the strict guidance of a healthcare professional to monitor potential side effects and track therapeutic progress.

As a parastomal skin treatment, Acyclovir 5%/Hydrocortisone 2% Topical Cream may be beneficial. Parastomal skin disorders can occur as a complication from ostomy surgery, and treatment can be challenging due to the delicate nature of the skin and the proximity to mucous membranes around the stoma. The anti-inflammatory properties of hydrocortisone may provide relief. However, as with other uses outside of herpes simplex labialis, usage should be closely monitored by a healthcare provider.

Lastly, while the use of the Acyclovir 5%/Hydrocortisone 2% Topical Cream for diseases other than herpes simplex labialis does not have FDA approval, it can still be used under the care and prescription of a medical professional for individual needs. If you have any questions, please don't hesitate to reach out to us here at Bayview Pharmacy. Our team of compounding pharmacists is more than ready to provide detailed and individualized care to meet your needs.

Frequently Asked Questions

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What is this Acyclovir 5%/Hydrocortisone 2% Topical Cream used for?

This cream is typically used for the localized treatment of certain skin conditions, with the active ingredients designed to be absorbed by the skin upon application.

What does it mean when the medicine is described as a 'semisolid preparation'?

A semisolid preparation refers to the state of the medication. It's not entirely solid or liquid, but rather a consistency in-between. This cream, for instance, is semi-solid which allows for its smooth application on the skin.

How is the Acyclovir 5%/Hydrocortisone 2% Topical Cream packaged?

The cream is dispensed in a pump mechanism for convenient and controlled application. This means that you can dispense just the amount you need with each use, minimizing waste.

How should I store this cream?

Store the cream in a cool, dry place away from direct sunlight. Make sure to keep the pump mechanism closed when not in use, to prevent the cream from drying out or getting contaminated.

How should I apply this cream?

Apply a thin layer of the cream to the affected area of the skin as directed by your healthcare provider. Use the pump mechanism to dispense the cream, spread evenly using a clean finger.

Can this product be used on all areas of the skin?

Unless specified by your healthcare provider, this cream is designed for localized treatment, meaning it should be applied only to the area of the skin that requires treatment. It is not intended for widespread use.

What are the active ingredients in this cream?

The active ingredients in this cream are Acyclovir at a 5% concentration and Hydrocortisone at a 2% concentration.

What are the benefits of having a pump mechanism for the medication?

The pump mechanism allows for a controlled and convenient application of the cream. It helps to dispense a consistent amount of product each time it’s used, minimizing the risk of using too much or too little cream.

Can this cream be used in conjunction with other skincare products?

Before combining this medication with other skincare products, it is best to consult a healthcare provider, as some ingredients could interfere with the absorption or efficacy of Acyclovir and Hydrocortisone.

What precautions should I take when using this Acyclovir 5%/Hydrocortisone 2% Topical Cream?

Avoid contact with the eyes and mouth. Use the product strictly as directed by a healthcare provider. In case of any adverse reactions, stop using and consult your healthcare provider immediately.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Acyclovir 5%/Hydrocortisone 2% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)