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Aloe Vera 0.2%/Ketoprofen 2%/Lidocaine 2%/Misoprostol 0.0024%/Phenytoin Sodium 2% Topical Ointment

This Aloe Vera 0.2%/Ketoprofen 2%/Lidocaine 2%/Misoprostol 0.0024%/Phenytoin Sodium 2% Topical Ointment is a semi-solid formulation, dispensed in a tube for external application. It is designed to provide a greasy or oily base that aids in the delivery of medication or therapeutic agents for localized treatment. The formulation contains Aloe Vera, known for its soothing properties, Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), Lidocaine, a local anesthetic, Misoprostol, a prostaglandin, and Phenytoin Sodium, an anticonvulsant.

The ointment is typically used for conditions such as skin inflammation, infections, or wound healing. The combination of these active ingredients works synergistically to provide relief from pain, reduce inflammation, promote wound healing, and protect the skin. The formulation is designed to be applied directly to the affected area, providing targeted relief and treatment.

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Topical Ointment
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Formula Information

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This formulation is a multi-ingredient topical ointment that combines the therapeutic benefits of Aloe Vera, Ketoprofen, Lidocaine, Misoprostol, and Phenytoin Sodium. Each of these ingredients plays a unique role in treating various skin conditions and promoting wound healing.

Aloe Vera 0.2% is a natural ingredient known for its soothing and anti-inflammatory properties. It helps to reduce skin inflammation and promote healing. Ketoprofen 2% is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, reduce inflammation, and lower fever.

Lidocaine 2% is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is used on normal intact skin or on the outer genital area to prevent pain before certain procedures such as inserting a needle, skin grafts, or skin laser surgery.

Misoprostol 0.0024% is a synthetic prostaglandin E1 analog with gastric antisecretory and mucosal protective properties. Misoprostol is used to prevent NSAID-induced ulcers and has off-label uses for wound healing due to its ability to stimulate the secretion of mucus and bicarbonate, enhance mucosal blood flow, and promote the repair of epithelial tissue.

Phenytoin Sodium 2% is an anticonvulsant that has been found to promote wound healing by modulating the inflammatory response and promoting tissue regeneration. It is particularly useful in treating chronic, non-healing wounds.

This formulation is dispensed in a semi-solid form in a tube, designed for external application to the skin. The greasy or oily base aids in the delivery of the medication, ensuring that the therapeutic agents are effectively absorbed for localized treatment. It is typically used for conditions such as skin inflammation, infections, or wound healing.

For both patients and prescribers, it is important to note that this formulation should be used as directed by a healthcare professional. It should be applied to the affected area in the amount and frequency as prescribed. Avoid contact with eyes, mouth, and other mucous membranes. If any adverse reactions occur, such as excessive redness, irritation, or discomfort, discontinue use and consult your healthcare provider.

If you have any questions about this formulation or its use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This formulation contains a combination of Aloe Vera, Ketoprofen, Lidocaine, Misoprostol, and Phenytoin Sodium. Each of these ingredients has a specific role in treating various skin conditions, inflammation, infections, or aiding in wound healing. However, it's important to be aware of potential drug interactions that may occur with this formulation.

Aloe Vera is generally considered safe and has minimal interactions. However, it may decrease the absorption of oral drugs if applied topically at the same time. It's recommended to apply this ointment at least 2 hours before or after taking oral medications.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can increase the risk of bleeding when used with other drugs that have the same effect, such as anticoagulants (e.g., warfarin) and antiplatelet drugs (e.g., aspirin). It may also interact with other NSAIDs, corticosteroids, and certain blood pressure medications, potentially leading to kidney problems.

Lidocaine is a local anesthetic that can interact with other local anesthetics and certain antiarrhythmic drugs (e.g., mexiletine). Concurrent use may increase the risk of systemic toxicity. It's also important to avoid applying this ointment to large areas of skin or broken skin, as this can increase the absorption of lidocaine and potentially lead to toxicity.

Misoprostol is a prostaglandin analogue that can interact with antacids and other drugs that lower stomach acid, potentially reducing its effectiveness. It may also interact with certain drugs used for heart disease (e.g., digoxin) and diabetes (e.g., glyburide), potentially leading to adverse effects.

Phenytoin Sodium is an anticonvulsant that has numerous drug interactions. It can affect the metabolism of many drugs, potentially leading to increased or decreased drug levels. It's important to monitor for changes in therapeutic effects or adverse effects if other medications are started or stopped while using this ointment.

It's crucial to inform your healthcare provider of all medications you are currently taking, including prescription drugs, over-the-counter medications, and dietary supplements. This will help to identify potential drug interactions and adjust your treatment plan accordingly. If you have any questions or concerns, please don't hesitate to reach out to us at Bayview Pharmacy.

How Does it Work

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This topical ointment is a combination of five active ingredients: Aloe Vera, Ketoprofen, Lidocaine, Misoprostol, and Phenytoin Sodium. Each of these ingredients plays a unique role in treating various skin conditions and promoting wound healing.

Aloe Vera, a plant extract known for its soothing and healing properties, is included at a concentration of 0.2%. It helps to moisturize the skin, reduce inflammation, and promote wound healing. It also has antimicrobial properties that can help prevent infection in wounds or damaged skin.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing the production of prostaglandins, substances in the body that cause inflammation and pain. At a concentration of 2%, it helps to reduce inflammation and pain in the area where the ointment is applied.

Lidocaine, also present at a concentration of 2%, is a local anesthetic. It works by blocking nerve signals in your body, thereby reducing pain and discomfort in the treated area. This can be particularly beneficial in conditions where the skin is inflamed or damaged.

Misoprostol, included at a concentration of 0.0024%, is a synthetic prostaglandin E1 analogue. It works by promoting the healing of ulcers and preventing the formation of new ones. It also has anti-inflammatory properties that can help reduce inflammation in the skin.

Phenytoin Sodium, present at a concentration of 2%, is an anticonvulsant that also has beneficial effects on the skin. It promotes wound healing by modulating the inflammatory response and promoting the growth of healthy skin cells.

This formulation is designed to be applied topically, directly to the affected area of the skin. The semi-solid base provides a greasy or oily layer that aids in the delivery of the active ingredients, ensuring they are absorbed effectively into the skin for localized treatment. This makes it particularly suitable for treating conditions such as skin inflammation, infections, or promoting wound healing.

As with any medication, it's important to use this ointment as directed by your healthcare provider. If you have any questions about this formulation or how to use it, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help.

Other Uses

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This custom-compounded Aloe Vera 0.2%/Ketoprofen 2%/Lidocaine 2%/Misoprostol 0.0024%/Phenytoin Sodium 2% Topical Ointment may have other potential uses beyond those typically associated with each individual ingredient. Its full potential might not be limited to treating skin inflammation, infection, and promoting wound healing.

A unique combination of analgesics (ketoprofen and lidocaine), anti-inflammatories (Aloe Vera and ketoprofen), an anticonvulsant that also aids in wound healing (phenytoin sodium), and a medication usually used for stomach ulcers but known for its healing principles (misoprostol), can be utilized to address a wide spectrum of dermal conditions. The analgesic properties of this formula may help in alleviating pain associated with minor burns, sunburn, abrasions, insect bites, and localized nerve pain (neuralgia). Lidocaine, in particular, is a local anesthetic which may provide temporary relief for these conditions.

The anti-inflammatory components, aloe vera and ketoprofen, may provide relief for various types of dermatitis, minor skin irritations, and may alleviate discomfort from poison ivy or oak. Phenytoin, typically used as an anticonvulsant, has also been shown to promote healing in difficult wounds.

Furthermore, because misoprostol helps replace prostaglandins in the body, it potentially could be utilized to repair skin injuries and minimize scarring, although this usage is more experimental and not yet widely recognized.

It is vitally important that this information is used as a guide and patients should not use this ointment for prolonged periods without consulting their healthcare provider. It is recommended that prescribers inform their patients of the potential other uses of this formulation to ensure correct usage and mitigate any potential misuse or adverse effects. If you, the prescriber or the patient, have any questions regarding this formulation, please reach out to us for further clarification and guidance.

Frequently Asked Questions

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What is this compounded formulation meant for?

This is a topical ointment meant to treat conditions such as skin inflammation, infections, or wound healing. It contains medications that work together to soothe the skin, relieve pain, treat skin infections, and promote healing.

How is this ointment applied?

This ointment is designed for external application to the skin. Just apply a thin layer to the affected area and rub it in gently until it is absorbed.

What do the different components in this ointment do?

This ointment contains Aloe Vera to soothe the skin, Ketoprofen as a pain reliever, Lidocaine as a local anesthetic, Misoprostol to assist in wound healing and Phenytoin Sodium to treat skin infections.

Can this ointment be used for any type of skin condition?

This ointment is typically used for skin inflammation, infections, or wound healing. However, it's always best to consult with your healthcare provider for specific treatments related to your skin condition.

Does the ointment leave a greasy or oily feeling?

Yes, the ointment has a greasy or oily base. This aids in the delivery of the medication and therapeutic agents to the skin.

What form does this medication come in?

This medication is a semi-solid formulation dispensed in a tube.

Is there a specific way to store this medication?

You should store this medication at controlled room temperature. Be sure to keep the tube tightly closed when not in use.

Does this compounded formulation have any side effects?

Like any medication, this compounded formulation can have side effects. If you experience any unusual symptoms or reactions after applying the ointment, you should contact your healthcare provider immediately.

How often should this ointment be applied?

The frequency of application can vary depending on the individual and the condition being treated. Therefore, it is always best to follow the instructions provided by your healthcare provider.

Do I need a prescription for this ointment?

Yes, this is a compounded medication which means it is custom made in a pharmacy based on a doctor's prescription. It is not available over-the-counter."

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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