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Aloe Vera 0.2%/Lidocaine HCl 2%/Metronidazole 2%/Pentoxifylline 5%/Phenytoin Sodium 5% Topical Cream

This formulation is a semisolid preparation, dispensed in a pump mechanism for convenient and controlled application on the skin. It contains Aloe Vera 0.2%, Lidocaine HCl 2%, Metronidazole 2%, Pentoxifylline 5%, and Phenytoin Sodium 5%. The cream is designed for localized treatment or absorption of these active ingredients.

Aloe Vera is known for its soothing and healing properties, making it beneficial for skin irritations. Lidocaine HCl is a local anesthetic used to numb the skin and relieve pain or discomfort. Metronidazole is an antibiotic that fights bacteria in the body, while Pentoxifylline is used to improve blood flow. Phenytoin Sodium is an anticonvulsant that also helps to slow down infections and promote healing.

This topical cream is used to treat a variety of disease states. It can be used for skin conditions such as burns, wounds, and ulcers. It is also effective in treating bacterial skin infections and improving blood flow in the affected area. The cream's anesthetic properties make it useful for relieving pain associated with these conditions.

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Topical Cream
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Formula Information

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This formulation is a unique blend of Aloe Vera 0.2%, Lidocaine HCl 2%, Metronidazole 2%, Pentoxifylline 5%, and Phenytoin Sodium 5% in a topical cream. It is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients.

Aloe Vera, known for its soothing and healing properties, helps to reduce inflammation and promote wound healing. Lidocaine HCl is a local anesthetic that provides temporary relief from pain and discomfort. Metronidazole is an antibiotic that fights bacteria in the body, particularly effective in treating skin infections. Pentoxifylline is a xanthine derivative that improves blood flow, aiding in the healing process of the skin. Phenytoin Sodium is an anticonvulsant that also promotes healing in hard-to-heal wounds.

This formulation is particularly useful in treating a variety of skin conditions, including but not limited to, wound healing, skin infections, burns, and ulcers. The combination of these active ingredients works synergistically to provide pain relief, fight infection, reduce inflammation, and promote healing.

Patients should apply the cream to the affected area as directed by their healthcare provider. The cream should be used consistently for the full prescribed length of time, even if symptoms improve before the infection is completely cleared. Side effects may include mild irritation or redness at the application site. If these effects persist or worsen, contact your healthcare provider immediately.

Prescribers should consider this formulation for patients with skin conditions that require a multifaceted approach to treatment. The combination of active ingredients provides a comprehensive solution to pain management, infection control, and wound healing. As with any medication, it is important to consider the patient's overall health status, potential drug interactions, and possible allergies before prescribing.

If you have any questions about this formulation, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to assist you.

Drug Interactions

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This topical cream formulation contains a combination of Aloe Vera, Lidocaine HCl, Metronidazole, Pentoxifylline, and Phenytoin Sodium. Each of these ingredients has its own potential for drug interactions, which can be amplified when used in combination. It's important for patients and prescribers to be aware of these potential interactions to ensure safe and effective use of this formulation.

Aloe Vera is generally considered safe for topical use and has minimal interactions. However, it may enhance the absorption of other topical medications, potentially increasing their effects and side effects. Therefore, caution should be exercised when using this formulation with other topical medications.

Lidocaine HCl is a local anesthetic that can interact with other local anesthetics and medications that are known to affect heart rhythm. These include antiarrhythmics, certain antidepressants, and some antipsychotics. Concurrent use with these medications could potentially lead to serious heart problems.

Metronidazole is an antibiotic that can interact with alcohol, leading to a disulfiram-like reaction characterized by nausea, vomiting, and flushing. Although this is more common with oral or systemic use of metronidazole, it's still recommended to avoid alcohol during treatment with this formulation. Metronidazole can also interact with blood thinners, increasing the risk of bleeding.

Pentoxifylline is a medication used to improve blood flow. It can interact with blood thinners, increasing the risk of bleeding. It can also interact with antihypertensive medications, potentially leading to excessively low blood pressure. Therefore, caution should be exercised when using this formulation in patients taking these medications.

Phenytoin Sodium is an anticonvulsant that has a wide range of drug interactions. It can interact with other anticonvulsants, altering their levels and effects. It can also interact with certain antibiotics, antifungals, and antiretroviral drugs, potentially leading to serious side effects. Therefore, a thorough medication review should be conducted before starting treatment with this formulation.

This formulation is designed for localized treatment or absorption of active ingredients, which can reduce the risk of systemic drug interactions. However, it's still important to consider potential interactions, especially in patients with extensive skin lesions or those using the cream over large areas of the body.

If you have any questions about this formulation or its potential drug interactions, please don't hesitate to reach out to us. We're here to help ensure the safe and effective use of this medication.

How Does it Work

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This topical cream formulation combines the therapeutic benefits of Aloe Vera, Lidocaine HCl, Metronidazole, Pentoxifylline, and Phenytoin Sodium. Each of these ingredients plays a unique role in treating various disease states, and their combined effect provides a comprehensive treatment approach.

Aloe Vera, at a concentration of 0.2%, is known for its soothing and healing properties. It helps to moisturize the skin, promote wound healing, and has anti-inflammatory effects. This makes it beneficial in managing skin irritations and promoting the healing of wounds or burns.

Lidocaine HCl, at a concentration of 2%, is a local anesthetic. It works by blocking nerve signals in your body, thereby reducing pain or discomfort caused by skin conditions or wounds. It provides immediate, localized relief from pain and discomfort.

Metronidazole, at a concentration of 2%, is an antibiotic that works by stopping the growth of bacteria and protozoa. This makes it effective in treating bacterial infections of the skin, such as infected wounds or ulcers.

Pentoxifylline, at a concentration of 5%, is a xanthine derivative that improves blood flow and reduces inflammation. It is often used to treat circulatory disorders and can help improve wound healing, particularly in conditions like venous leg ulcers.

Phenytoin Sodium, at a concentration of 5%, is an anticonvulsant that also promotes wound healing. It works by modulating cellular membrane stability and reducing the risk of seizures. In the context of this topical cream, it aids in the healing of neuropathic ulcers and other skin lesions.

This formulation is dispensed in a semisolid preparation via a pump mechanism, which allows for convenient and controlled application on the skin. The active ingredients are absorbed locally, providing targeted treatment for the affected area.

It's important to note that while this formulation can provide significant relief and promote healing, it should be used under the guidance of a healthcare provider. Always follow the prescribed dosage and application instructions to ensure the best possible outcome. If you have any questions or concerns about this formulation, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help.

Other Uses

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This unique compounding formulation of Aloe Vera 0.2%/Lidocaine HCl 2%/Metronidazole 2%/Pentoxifylline 5%/Phenytoin Sodium 5% Topical Cream has several potential uses outside of its primary purpose. With a blend of ingredients designed to soothe, numb, treat infection, improve blood flow, and reduce skin inflammation, its applications are impressively multifaceted.

For instance, beyond treating localized infections or inflammations, this compound can serve as a powerful analgesic cream for conditions causing skin pain. The presence of Lidocaine HCl in the formulation makes it a potential candidate for managing chronic pain conditions like peripheral neuropathy or post-herpetic neuralgia.

The inclusion of Aloe Vera and Pentoxifylline also contributes to tissue healing and rejuvenation, which may allow this product to be used for wound care management, especially in chronic wounds or wounds associated with conditions like diabetes or poor circulation.

Additionally, the Phenytoin Sodium in this concoction could make it a valuable adjuvant in the treatment of certain skin conditions associated with cell proliferation, such as psoriasis and, when used under the guidance of a medical professional, potentially some types of skin cancer.

The antimicrobial Metronidazole serves not only in managing infections but may also be helpful in addressing skin conditions linked to bacteria, such as rosacea or certain forms of acne.

While the possibilities are extensive, usage of this formulation should always be guided by a medical professional to ensure safety and efficacy. It's important that patients inform their healthcare provider of all medications they are currently taking, as well as any allergies they may have, to avoid potential drug interactions or adverse reactions. Always follow the prescribed directions for use to maximize the potential benefits of this unique, compounded formulation.

If you have any questions regarding the use of this formulation for other conditions, or if you want more in-depth information regarding the properties of individual ingredients and their potential applications, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of expert compounding pharmacists is always ready to assist you.

Frequently Asked Questions

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What is this compounded formulation?

This compounded formulation is a topical cream that comprises of Aloe Vera 0.2%/ Lidocaine HCl 2%/ Metronidazole 2%/ Pentoxifylline 5%/ Phenytoin Sodium 5%. It is dispensed via a pump mechanism and is applied directly on the skin for localized treatment.

What is the function of each ingredient in the formulation?

Aloe Vera has healing and soothing properties. Lidocaine HCl is a local anesthetic that numbs the skin. Metronidazole is an antibiotic to treat infections. Pentoxifylline improves blood flow and Phenytoin Sodium is normally used for the management of seizures.

How does this cream function?

This cream combines the properties of its different active ingredients to deliver local treatment or absorption when applied topically to the skin.

How is the cream applied?

The cream is dispensed using a pump mechanism and should be applied topically to the skin, as needed, or as instructed by a healthcare professional.

What is a semisolid preparation?

A semisolid preparation is a form of drug product that is not as hard as solids and not as fluid as liquids. This formulation is generally designed for better adherence and sustained contact with the skin to enhance the absorption of the medication.

Can this cream be used on open wounds or sores?

Please consult with your healthcare professional before applying this cream on open wounds or sores. The decision will depend on the type of wound and the ingredients in the cream.

Is this cream safe for everyone to use?

As with any medication, this cream should be used under the supervision of a healthcare professional. It may not be suitable for people who are allergic to any of its ingredients. Always consult a healthcare professional before starting any new medication.

Can the cream cause skin irritation?

While the cream is generally well-tolerated, some individuals may experience skin irritation. If skin irritation or any other adverse reaction occurs, discontinue use and consult a healthcare professional.

Can this product be used in conjuction with other topical medications?

Before using this product in conjunction with other topical medications, you should discuss it with your healthcare provider. They can advise you on potential interactions and whether it is safe to do so.

How should this cream be stored?

Store this cream in a cool, dry place away from light and moisture. Keep out of reach of children and pets. Follow the storage instructions given by your pharmacist or healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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