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Formulas

Amantadine HCl 0.25%/Baclofen 0.25%/Ketoprofen 1% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Amantadine Hydrochloride
Ketoprofen
Baclofen

This formulation is a semisolid compound of Amantadine HCl 0.25%, Baclofen 0.25%, and Ketoprofen 1% in a topical gel. It is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The Amantadine HCl component is an antiviral medication that also has antiparkinsonian properties. Baclofen is a muscle relaxant and antispastic agent, while Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). Together, these ingredients work to treat a variety of disease states, including Parkinson's disease, muscle spasms, and inflammation.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Amantadine Hydrochloride
Ketoprofen
Baclofen
Topical Gel
652fee3d3f007b23c95c0e68
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation combines Amantadine HCl 0.25%, Baclofen 0.25%, and Ketoprofen 1% in a topical gel. It is a semisolid formulation that is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed directly into the targeted area, providing localized treatment.

Amantadine HCl is an antiviral medication that also has properties to relieve pain, particularly neuropathic pain. It works by blocking the action of certain chemicals in the body that may contribute to the sensation of pain. Baclofen is a muscle relaxer and an antispasmodic agent. It is used to treat muscle symptoms such as spasm, pain, and stiffness. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body.

This combination of medications in a topical gel form is particularly useful in treating conditions such as neuropathic pain, muscle spasms, and inflammation. By applying the medication directly to the affected area, patients can experience targeted relief with potentially fewer systemic side effects compared to oral medications.

It is important for patients to use this medication as directed by their healthcare provider. The gel should be applied to the affected area and gently massaged until it is fully absorbed. Patients should avoid contact with eyes, nose, mouth, and other sensitive areas. If the medication gets in these areas, rinse with water immediately. It is also crucial to wash hands after applying unless hands are the area being treated.

As with any medication, this formulation may cause side effects. Common side effects may include skin irritation at the application site. If these effects persist or worsen, contact your healthcare provider immediately. Serious side effects are rare but seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.

For prescribers, it is important to consider the patient's overall health status, other medications, and potential drug interactions when prescribing this formulation. Regular follow-ups are recommended to monitor the patient's response to treatment and adjust the dosage if necessary.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This formulation combines Amantadine HCl, Baclofen, and Ketoprofen in a topical gel. Each of these active ingredients has its own potential drug interactions, which can be exacerbated when used in combination. It's important to note that while this formulation is designed for topical use, systemic absorption can still occur, potentially leading to interactions with other medications taken orally or intravenously.

Amantadine HCl is an antiviral medication that also has properties for treating Parkinson's disease and certain other movement disorders. It can interact with several types of medications, including anticholinergic drugs, antihistamines, and other medications used to treat Parkinson's disease. Concurrent use with these medications can increase the risk of side effects such as dry mouth, blurred vision, and urinary retention. Additionally, Amantadine can interact with live influenza vaccines, potentially reducing their effectiveness.

Baclofen is a muscle relaxant and antispastic agent. It can interact with other central nervous system depressants, including alcohol, antihistamines, sedatives, and opioids, potentially leading to increased sedation and respiratory depression. Baclofen can also interact with medications that affect kidney function, as it is primarily excreted via the kidneys. Patients with impaired kidney function or those taking medications that can affect kidney function should use Baclofen with caution.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. It can interact with other NSAIDs, increasing the risk of gastrointestinal bleeding and ulcers. Ketoprofen can also interact with blood thinners, antihypertensive drugs, and certain types of antidepressants. Additionally, it can reduce the effectiveness of certain heart medications.

This formulation is intended for targeted treatment of pain and inflammation, and may also be used in the management of certain movement disorders. However, due to the potential for drug interactions, it's important for patients to inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs and dietary supplements. This will help to ensure safe and appropriate use of this medication.

If you have any questions about this formulation or its potential interactions with other medications, please don't hesitate to reach out to us. Our team of compounding pharmacists at Bayview Pharmacy is always here to help.

How Does it Work

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This unique formulation combines three active ingredients: Amantadine HCl, Baclofen, and Ketoprofen, each with its own mechanism of action to provide relief from various disease states.

Amantadine HCl is an antiviral medication that also has properties to treat Parkinson's disease and similar conditions. It works by blocking the actions of certain chemicals in the body that may contribute to the symptoms of Parkinson's disease. In a topical formulation, it can help to reduce muscle stiffness and tremors.

Baclofen is a muscle relaxer and an antispastic agent. It works by restoring the balance of certain natural substances (such as gamma-aminobutyric acid, GABA) in the brain. Baclofen in this topical gel can help to reduce muscle spasms, tightness, and pain.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. When applied topically, Ketoprofen can provide targeted relief from pain and inflammation in specific areas of the body.

The gel formulation allows for easy and precise application of the medication directly to the affected area. The active ingredients are absorbed through the skin, providing targeted treatment and reducing the potential for systemic side effects. This makes it an excellent option for patients who may have difficulty with oral medications or who require targeted relief from symptoms.

This formulation can be used to treat a variety of disease states, including but not limited to, Parkinson's disease, muscle spasms, and pain and inflammation associated with various conditions. As with any medication, it's important to use this formulation under the guidance of a healthcare provider and to discuss any potential side effects or interactions with other medications.

If you have any questions about this formulation, how it works, or how it can be used to treat specific conditions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Frequently Asked Questions

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What is Amantadine HCl 0.25%/Baclofen 0.25%/Ketoprofen 1% Topical Gel?

It is a compounded medication containing Amantadine HCl, Baclofen, and Ketoprofen in a semisolid formulation. It is designed to be absorbed through the skin for targeted treatment and is dispensed through a pump mechanism for easy and precise application.

How do I use this topical gel?

To use this gel, apply a thin layer onto the skin in the targeted area as directed by a healthcare provider. The pump mechanism allows for precise application.

What are the active ingredients in this formulation?

The active ingredients in this formulation are Amantadine HCl, Baclofen, and Ketoprofen.

What is the consistency of this topical gel?

The Amantadine HCl/Baclofen/Ketoprofen Topical Gel has a gel-like consistency.

Can I use this formulation anywhere on the body?

This compound formulation is designed to be applied directly to the skin in the specific area that requires treatment. It is not to be used on mucus membranes, open wounds, or near the eyes or mouth unless directed by a healthcare provider. Always follow the direction of your healthcare provider for application.

How is the dose measured for this topical gel?

The dose is measured via the pump mechanism attached to the container. This allows for a consistent dose to be easily dispensed and applied.

What are the possible side effects of this topical gel?

As with any medication, side effects may occur. Possible side effects include skin irritation at the application site, dizziness, or headache. If you experience any persistent or severe side effects, you should contact your healthcare provider immediately.

Can I use other topical medications while using this gel?

Before starting any new medication, including topical treatments, you should discuss it with your healthcare provider. Some medications may interact with this formulation, altering its effectiveness or resulting in unwanted side effects.

How should this topical gel be stored?

This medication should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

What should I do if I miss a dose of this medication?

If you realize you've missed a dose, apply it as soon as possible. However, if it's close to the time for your next dose, skip the missed one and continue with your regular schedule. Do not double up on doses to compensate for a missed one without consulting with your healthcare provider.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Amantadine HCl 0.25%/Baclofen 0.25%/Ketoprofen 1% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily