This formulation is a compounded topical ointment containing Amitriptyline 8%, Cyclobenzaprine 2%, Diclofenac 9%, DMSO 5%, Lidocaine 4%, and Menthol 2%. It is designed to be applied externally to the skin, providing localized treatment for a variety of conditions.

Amitriptyline is a tricyclic antidepressant that has been found to be effective in treating certain types of chronic pain, particularly neuropathic pain. It works by increasing the levels of certain chemicals in the brain that help improve mood, sleep, and the body's response to pain.

Cyclobenzaprine is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is used to relieve muscle spasms and to improve mobility.

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. It is used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis.

DMSO (Dimethyl Sulfoxide) is a chemical compound which is a by-product of wood processing. It has been used to help penetrate the skin and promote absorption of the other ingredients in the formulation.

Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is used to relieve pain and discomfort from skin irritations and minor cuts.

Menthol is a natural substance found in mint plants. It provides a cooling sensation when applied to the skin, helping to relieve minor pain and inflammation.

This formulation is dispensed in a semi-solid form in a tube, providing a greasy or oily base that aids in the delivery of the medication. It is typically used for conditions such as skin inflammation, infections, or wound healing. The combination of these ingredients provides a multi-modal approach to pain management, targeting different aspects of the pain pathway.

As with any medication, it is important to use this formulation as directed by your healthcare provider. If you have any questions or concerns about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to assist you.

This topical ointment contains a combination of Amitriptyline, Cyclobenzaprine, Diclofenac, DMSO, Lidocaine, and Menthol. Each of these ingredients has a specific role in treating various skin conditions, inflammation, infections, or aiding in wound healing. However, it's important to be aware of potential drug interactions that may occur with this formulation.

Amitriptyline, a tricyclic antidepressant, may interact with other antidepressants, antipsychotics, certain antihistamines, and drugs that affect serotonin levels, such as St. John's wort. It can also interact with certain heart medications and increase the risk of side effects.

Cyclobenzaprine, a muscle relaxant, may interact with other CNS depressants like alcohol, barbiturates, benzodiazepines, and narcotics. Combining these substances can lead to increased sedation and potentially dangerous respiratory depression. It can also interact with certain antidepressants, leading to a potentially life-threatening condition called serotonin syndrome.

Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), may interact with other NSAIDs, blood thinners, and certain blood pressure medications. These interactions can increase the risk of bleeding and kidney damage. It can also interact with certain heart medications, potentially reducing their effectiveness.

DMSO (Dimethyl Sulfoxide) is a solvent that helps in the absorption of the other ingredients in the ointment. It may interact with certain blood thinners, increasing the risk of bleeding. It can also interact with certain diabetes medications, potentially causing hypoglycemia.

Lidocaine, a local anesthetic, may interact with other local anesthetics and certain heart medications. These interactions can increase the risk of serious side effects such as slow heart rate, low blood pressure, and seizures.

Menthol, used for its cooling and analgesic properties, generally has fewer interactions. However, it can cause skin irritation in some people, especially when used with other topical medications.

It's important to inform your healthcare provider of all medications, supplements, and herbal products you are currently taking before starting this treatment. If you experience any unusual symptoms or side effects, contact your healthcare provider immediately. This formulation should only be used as directed by a healthcare professional and should not be used in larger amounts or for longer than recommended.

If you have any questions or concerns about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need.

This topical ointment is a combination of several active ingredients, each with a specific role in managing pain and inflammation. The formulation is designed to be applied directly to the skin, where it can act locally on the affected area. The greasy or oily base of the ointment aids in the delivery of the medication, ensuring that the active ingredients are absorbed effectively.

Amitriptyline (8%) is a tricyclic antidepressant that has been found to be effective in managing chronic pain, particularly neuropathic pain. It works by increasing the levels of certain chemicals in the brain that help elevate the pain threshold so that you feel less pain. In a topical formulation, amitriptyline can provide localized pain relief without the systemic side effects associated with oral administration.

Cyclobenzaprine (2%) is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is particularly effective in treating muscle spasms and associated pain.

Diclofenac (9%) is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. It is commonly used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis.

DMSO (5%) is a solvent that enhances the absorption of the other ingredients in the formulation. It helps in penetrating the skin and improving the delivery of the other active ingredients to the site of pain or inflammation.

Lidocaine (4%) is a local anesthetic that works by causing temporary numbness in the area where it is applied. It works by blocking nerve signals in your body and is often used to reduce pain or discomfort caused by skin irritations.

Menthol (2%) produces a cooling effect by stimulating the nerves that perceive cold sensations and by dilating the blood vessels, which can help to relieve pain. It also provides a soothing sensation that can help to distract from the pain.

This formulation is typically used for conditions such as skin inflammation, infections, or wound healing. It provides localized treatment, delivering the active ingredients directly to the area where they are needed, which can help to reduce side effects compared to oral medications.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other than its primary use for managing inflammation, infections and promoting wound healing, this Amitriptyline 8%/Cyclobenzaprine 2%/Diclofenac 9%/DMSO 5%/Lido 4%/Menthol 2% Topical Ointment offers several potential therapeutic benefits due to the properties of the compounds included in the formulation.

First, Amitriptyline, a tricyclic antidepressant often used to treat chronic pain and migraine prophylaxis, may offer potential relief for nerve-related pain conditions such as post-herpetic neuralgia or neuropathic pain associated with diabetes. The Cyclobenzaprine component, a muscle relaxant, could be used off-label to ease muscle spasms or tension, often accompanying musculoskeletal conditions like fibromyalgia or temporomandibular joint (TMJ) disorder.

Furthermore, Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) known for reducing joint inflammation, hence could be beneficial for people with osteoarthritis or rheumatoid arthritis. DMSO, or dimethyl sulfoxide, renowned for its penetrant properties, may improve the absorption and efficacy of other ingredients in the formulation. It may also exhibit anti-inflammatory and analgesic effects itself.

Lidocaine (Lido) is a local anaesthetic and antiarrhythmic agent that can provide topical pain relief from conditions such as burns, stings, or minor skin procedures. Finally, Menthol, typically used for its cooling sensation, may additionally aid in temporary relief from minor arthritis and muscle aches, itching and sunburns.

It's important to note that while this formulation can potentially cover a wide range of conditions, the efficacy and safety in these other uses might vary. Therefore, it's essential for patients and prescribers to discuss these off-label benefits and any potential risks before choosing this therapy. Finally, always use this formulation as directed by your healthcare professional and feel free to reach out to us with any questions regarding this formulation.