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Amitriptyline HCl 2.5%/Gabapentin 3%/Lidocaine 4.44%/Meloxicam 0.5%/Topiramate 1.25% Topical Ointment

FDA-approved generic
Dose form
Topical Ointment
Active ingredients
Amitriptyline Hydrochloride
Gabapentin
Meloxicam
Topiramate
Lidocaine Hydrochloride

This formulation is a compounded topical ointment containing Amitriptyline HCl 2.5%, Gabapentin 3%, Lidocaine 4.44%, Meloxicam 0.5%, and Topiramate 1.25%. It is a semi-solid preparation dispensed in a tube for external application to the skin. The greasy or oily base of the ointment aids in the delivery of these therapeutic agents for localized treatment.

The combination of these active ingredients is designed to address various disease states. Amitriptyline HCl is a tricyclic antidepressant that can help manage chronic pain. Gabapentin is an anticonvulsant that can also treat nerve pain. Lidocaine is a local anesthetic that provides temporary relief from pain and discomfort. Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that can reduce pain, swelling, and stiffness of the joints. Lastly, Topiramate is an anticonvulsant that can help manage nerve pain and prevent migraines.

This formulation is typically used for conditions such as skin inflammation, infections, or wound healing. It provides a targeted approach to pain management, reducing systemic side effects and improving patient compliance.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Amitriptyline Hydrochloride
Gabapentin
Meloxicam
Topiramate
Lidocaine Hydrochloride
Topical Ointment
65308c3fa8914071f6f5af62
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation is a compounded topical ointment containing Amitriptyline HCl 2.5%, Gabapentin 3%, Lidocaine 4.44%, Meloxicam 0.5%, and Topiramate 1.25%. It is a semi-solid preparation that is applied externally to the skin. The greasy or oily base of the ointment aids in the delivery of the medication, providing localized treatment.

Amitriptyline HCl is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It can help to alleviate chronic pain, particularly neuropathic pain, by blocking the reuptake of serotonin and norepinephrine in the brain, thereby increasing their levels and enhancing their pain-relieving effects.

Gabapentin is an anticonvulsant that is also used to treat neuropathic pain. It works by reducing abnormal electrical activity in the brain, which can help to alleviate pain sensations. Lidocaine is a local anesthetic that provides immediate relief from pain by blocking nerve signals in the body.

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain in the body by blocking the production of certain substances that cause inflammation. Topiramate is an anticonvulsant that is used to treat nerve pain and can also help to reduce the frequency of migraines.

This formulation is typically used for conditions such as skin inflammation, infections, or wound healing. The combination of these medications in a topical ointment allows for targeted treatment of these conditions, reducing systemic side effects that can occur with oral administration of these medications.

It is important for patients and prescribers to understand that this is a compounded medication, meaning it is made specifically for the patient and may not be suitable for everyone. As with any medication, there may be potential side effects and interactions with other medications. Therefore, it is crucial to discuss your medical history and current medications with your healthcare provider before starting this treatment.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This topical ointment contains a combination of Amitriptyline HCl, Gabapentin, Lidocaine, Meloxicam, and Topiramate. Each of these active ingredients has its own potential for drug interactions, which can be increased when used in combination. It's important to inform your healthcare provider of all medications you are currently taking, including prescription drugs, over-the-counter medications, and dietary supplements.

Amitriptyline HCl, a tricyclic antidepressant, can interact with MAO inhibitors, SSRIs, anticholinergic drugs, and certain antihypertensive medications. It can also increase the effects of alcohol and other CNS depressants. Gabapentin, an anticonvulsant, can increase the effects of CNS depressants and may interact with antacids containing magnesium or aluminum.

Lidocaine, a local anesthetic, can interact with antiarrhythmic drugs and other local anesthetics. Meloxicam, a nonsteroidal anti-inflammatory drug (NSAID), can interact with anticoagulants, aspirin, other NSAIDs, and certain antihypertensive medications. Topiramate, an anticonvulsant, can interact with oral contraceptives, certain diuretics, and other anticonvulsants.

This formulation is designed for topical use and is intended to provide localized treatment for conditions such as skin inflammation, infections, or wound healing. The combination of these medications works synergistically to provide pain relief, reduce inflammation, and promote healing. Amitriptyline HCl and Gabapentin can help to manage neuropathic pain, Lidocaine provides local anesthesia, Meloxicam reduces inflammation, and Topiramate can help to reduce nerve pain.

While this formulation is designed for topical use, it's important to remember that systemic absorption can still occur, especially when applied to large areas of skin or over prolonged periods of time. This can increase the risk of systemic side effects and drug interactions. Therefore, it's important to use this medication as directed by your healthcare provider and to regularly monitor for potential side effects.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We are here to provide you with the information and support you need to use this medication safely and effectively.

How Does it Work

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This topical ointment is a combination of five active ingredients: Amitriptyline HCl, Gabapentin, Lidocaine, Meloxicam, and Topiramate. Each of these ingredients works in a unique way to provide relief from various symptoms associated with skin inflammation, infections, or wound healing.

Amitriptyline HCl is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It works by increasing the levels of certain chemicals in the brain that help elevate the mood and reduce the sensation of pain. When applied topically, it can help to numb the skin and reduce pain in the applied area.

Gabapentin is an anticonvulsant that is also known for its ability to relieve pain, particularly neuropathic pain. It works by affecting the way the nerves send messages to the brain, thereby reducing the sensation of pain. When applied topically, it can help to reduce pain and discomfort in the area of application.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. When applied to the skin, it causes a temporary loss of sensation in the area of application, providing immediate relief from pain and discomfort.

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing the production of certain substances in the body that cause inflammation. When applied topically, it can help to reduce swelling, redness, and pain in the area of application.

Topiramate is an anticonvulsant that is used in this formulation for its ability to reduce nerve pain. It works by calming the nerves and reducing the number of pain signals sent to the brain. When applied topically, it can help to reduce pain and discomfort in the area of application.

This semi-solid formulation is designed to be applied directly to the skin, providing localized treatment for the affected area. The greasy or oily base of the ointment aids in the delivery of the medication, allowing it to penetrate the skin and provide relief from symptoms. It is typically used for conditions such as skin inflammation, infections, or wound healing.

It's important to note that while this formulation can provide significant relief from symptoms, it is not a cure for the underlying condition. It should be used as part of a comprehensive treatment plan, under the supervision of a healthcare provider.

If you have any questions about this formulation, how it works, or how it can be used in your treatment plan, please don't hesitate to reach out to us. We are here to help.

Other Uses

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This combined formulation of Amitriptyline HCl 2.5%, Gabapentin 3%, Lidocaine 4.44%, Meloxicam 0.5%, and Topiramate 1.25% topical ointment, beyond treating skin inflammation, infections, or aiding in wound healing, has additional potential uses.

The Amitriptyline HCl has been used for its antidepressant characteristics as well as for managing various forms of neuropathic pain conditions, while the Gabapentin is a proven agent used in treating nerve pain conditions. These two, working in synergy, potentially make this ointment useful in managing localized neuropathic pain conditions which could result from shingles, nerve damage or other neuropathic disorders.

Lidocaine, a local anaesthetic, imbues this ointment with potential uses in both numbing areas for minor surgical procedures and in providing temporary relieving pain associated with minor burns, abrasions, and cuts. Alongside with Meloxicam, a non-steroidal anti-inflammatory drug (NSAID), this formulation can also be useful in local symptomatic relief of joint pains or strains due to arthritis, bursitis and other similar conditions.

Meanwhile, Topiramate, an anticonvulsant, can prove beneficial in treating certain types of seizures in people who have epilepsy. The application of this compound in the formulation gives it potential for use in part of a treatment plan for individuals suffering from epileptic seizures, possibly providing site-specific relief from cutaneous allodynia, a pain caused by a light touch or stroke to the skin commonly seen in individuals with migraines.

This comprehensive formulation might also have ancillary benefits, such as reducing restlessness or anxiety due to its sedative properties and serving as a treatment for certain cases of fibromyalgia or other muscle-related conditions. It's worthwhile noting, however, that these secondary uses are potential applications, and that robust clinical trials and individual consultation with healthcare professionals are essential before attempting these uses.

If you have any questions about these additional potential uses or regarding any other details on this formulation of Amitriptyline HCl, Gabapentin, Lidocaine, Meloxicam, and Topiramate topical ointment, we encourage you to reach out to us at Bayview Pharmacy. Our expert team of compounding pharmacists is always ready to help.

Frequently Asked Questions

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What is Amitriptyline HCl 2.5%/Gabapentin 3%/Lidocaine 4.44%/Meloxicam 0.5%/Topiramate 1.25% Topical Ointment?

This is a semi-solid formulation designed for application to the skin. It contains five active ingredients - Amitriptyline HCl, Gabapentin, Lidocaine, Meloxicam, and Topiramate - to provide localized treatment for various skin conditions.

How should this ointment be used?

This topical ointment is intended for external use only. It should be applied directly to the area of skin recommended by your healthcare provider, typically for treating skin inflammation, infections, or promoting wound healing.

What does the greasy or oily base do?

The greasy or oily base aids in the delivery of the medication to the skin. It helps in promoting the absorption of the therapeutic agents into the affected area and provides additional moisturizing benefits.

What are the active ingredients in this ointment?

The active ingredients in this ointment are Amitriptyline HCl, Gabapentin, Lidocaine, Meloxicam, and Topiramate. These are all compounds that have therapeutic effects on various skin conditions.

How does each active ingredient work?

Amitriptyline HCl is an antidepressant that may help relieve certain types of pain. Gabapentin is used to control seizures and relieve nerve pain. Lidocaine is a local anesthetic, providing temporary relief from pain or discomfort. Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain. Topiramate is used primarily for controlling seizures or preventing migraines, but it can have contemporary applications, as well.

Can anyone use this Amitriptyline HCl 2.5%/Gabapentin 3%/Lidocaine 4.44%/Meloxicam 0.5%/Topiramate 1.25% Topical Ointment?

This ointment should only be used under the supervision and according to the instructions of a healthcare professional. Not everyone may be suitable for this medication due to potential allergic reactions or interactions with other medications.

Can I use this ointment for any skin problems?

Though this ointment contains ingredients that may help with various skin problems, it should be used exactly as directed by a healthcare professional for a specified condition.

Are there any side effects of using this ointment?

As with all medications, there may be potential side effects such as skin irritation, redness, or swelling at the site of application. If you experience any unexpected side effects, stop using the product and contact your healthcare provider immediately.

How should I store this ointment?

This ointment should be stored at room temperature, away from heat and direct sunlight. The tube should be kept tightly closed when not in use.

Can I use this ointment alongside other topical products?

If you need to use other skin products in the same area, it is important to consult with your healthcare provider first. They may need to adjust the usage schedule or recommend alternatives to avoid potential interactions.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Amitriptyline HCl 2.5%/Gabapentin 3%/Lidocaine 4.44%/Meloxicam 0.5%/Topiramate 1.25% Topical Ointment
Topical Ointment
30 g
controlled

Apply topically to affected area(s)

Three times daily