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Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Amitriptyline Hydrochloride
Clonidine Hydrochloride

Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream is a compounded medication, dispensed in a pump mechanism for easy and controlled application. It is designed for localized treatment on the skin, aiding in the management of conditions such as Fibromyalgia, Migraine, Neuropathic Pain, Anxiety, and Insomnia.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Amitriptyline Hydrochloride
Clonidine Hydrochloride
Topical Cream
6427079ea64324298f518656

Formula Information

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Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream is a specially compounded medication designed to address a range of conditions including chronic pain, migraines, fibromyalgia, neuropathy, and anxiety. This unique formulation combines the therapeutic benefits of two active ingredients, Amitriptyline HCl and Clonidine HCl, to deliver a synergistic effect in managing these conditions.

Amitriptyline HCl is a tricyclic antidepressant that functions by inhibiting the reuptake of serotonin and norepinephrine. This action helps to alleviate pain and enhance mood. On the other hand, Clonidine HCl is an alpha-2 agonist that operates by reducing the release of certain neurotransmitters, thereby helping to decrease anxiety and improve sleep. The combined effect of these two medications offers relief from a variety of chronic pain, migraine, fibromyalgia, neuropathy, and anxiety conditions.

This formulation is dispensed as a topical cream, a semisolid preparation designed for direct application to the skin. This method of delivery allows for a more targeted approach to treatment, as the medication is delivered directly to the site of action. The cream is dispensed in a pump mechanism, designed for convenient and controlled application, ensuring the right dosage is applied each time. This user-friendly design eliminates the need for additional preparation, making it an easy-to-use option for patients.

Bayview Pharmacy's Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream is a potent treatment option for those grappling with chronic pain, migraines, fibromyalgia, neuropathy, and anxiety conditions. If you have any queries about this formulation or wish to understand more about how it can assist you, please do not hesitate to contact us.

Drug Interactions

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Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream is a compounded formulation designed to provide relief from chronic pain, migraines, fibromyalgia, neuropathy, and anxiety. This semisolid preparation is dispensed in a pump mechanism, ensuring a convenient and controlled application on the skin for localized treatment or absorption of the active ingredients.

Amitriptyline, a tricyclic antidepressant, functions by inhibiting the reuptake of serotonin and norepinephrine. This action helps to alleviate pain and enhance mood. On the other hand, Clonidine, an alpha-2 agonist, operates by reducing the release of norepinephrine, thereby decreasing anxiety and improving sleep. The combination of these two medications in this formulation can offer significant relief from the aforementioned conditions.

However, it is crucial to be aware that this formulation may interact with other medications. These include other tricyclic antidepressants, monoamine oxidase inhibitors, and beta-blockers. Therefore, it is advisable to consult with a healthcare provider before starting this treatment, especially if you are currently on other medications.

Additionally, this formulation may cause certain side effects such as drowsiness, dry mouth, and blurred vision. It is important to monitor these potential side effects and seek medical advice if they persist or worsen. Always remember to use this medication as directed by your healthcare provider to ensure its effectiveness and safety.

How Does it Work

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Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream is a specially compounded medication designed to address a range of conditions including chronic pain, migraines, fibromyalgia, neuropathy, and anxiety. This unique combination of Amitriptyline, an antidepressant that works to reduce pain signals in the brain, and Clonidine, a medication that aids in reducing anxiety and stress, works synergistically to alleviate inflammation, pain, and anxiety.

When applied topically, this semisolid preparation is absorbed through the skin and enters the bloodstream, allowing it to be distributed throughout the body. The cream is dispensed in a pump mechanism, designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients. It should be applied to the affected area twice daily, or as directed by your healthcare provider. However, it is important to avoid using this medication on broken or irritated skin.

While generally well tolerated, some side effects may occur with the use of Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream. These may include dry skin, itching, burning, or redness at the application site. If any of these side effects occur, it is recommended to contact your healthcare provider.

If you have any questions about Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream, or would like to learn more about how it can help manage chronic pain, migraines, fibromyalgia, neuropathy, and anxiety, please do not hesitate to reach out. We are here to provide the information and support you need.

Other Uses

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The Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream is a compounded formulation that has been effectively used in the treatment of various conditions such as Fibromyalgia, Migraine, Neuropathic Pain, Anxiety, and Insomnia. It has also shown efficacy in managing chronic pain, depression, and hypertension. This semisolid preparation is dispensed in a pump mechanism, designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients.

The cream is applied topically to the affected area and is absorbed through the skin, providing targeted relief. However, it is crucial to avoid applying this formulation on open wounds or on areas of skin that are broken or irritated. It is also advised not to use this formulation in combination with other topical medications to prevent potential interactions or adverse reactions.

Patients should be aware that this formulation may cause skin irritation. Therefore, it is important to monitor for any signs of redness, itching, or burning. Additionally, this formulation may cause drowsiness, so caution should be exercised while operating machinery or driving. If you have any questions or concerns about this formulation, please do not hesitate to reach out for further information.

Frequently Asked Questions

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What is Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream?

This is a compounded formulation of two active ingredients, Amitriptyline HCl and Clonidine HCl, in a semisolid preparation. It is designed for convenient and controlled application on the skin for localized treatment or absorption.

How is this cream dispensed?

The cream is dispensed in a pump mechanism, which allows for easy and controlled application on the skin.

What is the purpose of the pump mechanism?

The pump mechanism is designed to provide a convenient and controlled way to apply the cream on the skin. It ensures that the right amount of cream is dispensed each time.

What are the active ingredients in this cream?

The active ingredients in this cream are Amitriptyline HCl at a concentration of 2% and Clonidine HCl at a concentration of 0.01%.

What is the function of Amitriptyline HCl in this cream?

Amitriptyline HCl is a tricyclic antidepressant that is used in this cream for its analgesic properties. It can help to relieve pain in localized areas when applied topically.

What is the function of Clonidine HCl in this cream?

Clonidine HCl is a medication that is often used to treat high blood pressure. In this cream, it is used for its potential to alleviate pain and inflammation when applied topically.

How should I apply this cream?

This cream should be applied to the affected area as directed by your healthcare provider. The pump mechanism allows for easy and controlled application.

Can this cream be used for all types of pain?

It is best to consult with your healthcare provider to determine if this cream is suitable for your specific condition.

Are there any side effects associated with this cream?

As with any medication, there may be potential side effects. It is important to discuss these with your healthcare provider before starting treatment with this cream.

Can I use this cream if I am pregnant or breastfeeding?

It is important to consult with your healthcare provider before using this cream if you are pregnant or breastfeeding. They will be able to advise you on the potential risks and benefits.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Amitriptyline HCl 2%/Clonidine HCl 0.01% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)