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Amphotericin B 50 mg Vaginal Suppository

The Amphotericin B 50 mg Vaginal Suppository is a solid dosage form designed for insertion into the vagina. Upon dissolution or melting, it releases medication to treat conditions such as Vulvovaginal Candidiasis, Bacterial Vaginosis, Trichomoniasis, Mucocutaneous Candidiasis, and Tinea Versicolor.

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This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
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Formula Information

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Amphotericin B 50 mg Vaginal Suppository is a specially compounded antifungal medication designed to treat a range of fungal infections. This medication is particularly effective in treating vaginal yeast infections, vulvovaginal candidiasis, and other fungal infections of the vagina. It can also be used to treat fungal infections of the urinary tract, skin, and nails.

This medication comes in the form of a solid dosage suppository that is inserted into the vagina. Once inserted, the suppository dissolves or melts, releasing the medication for local or systemic absorption. The active ingredient, Amphotericin B, works by inhibiting the growth of fungi, thereby treating the infection.

The recommended dosage of Amphotericin B 50 mg Vaginal Suppository is one suppository inserted intravaginally once daily for a period of 7-14 days. It is crucial for patients to complete the full course of treatment, even if symptoms improve after a few days. This ensures the complete eradication of the fungal infection. Patients are also advised to abstain from sexual intercourse while undergoing treatment with this medication.

While Amphotericin B 50 mg Vaginal Suppository is a safe and effective treatment for fungal infections, it may cause some side effects. These can include burning, itching, and irritation in the vaginal area. If patients experience any of these side effects, they should immediately contact their healthcare provider for advice.

At Bayview Pharmacy, we are committed to providing our patients with high-quality compounded medications. If you have any questions or concerns about Amphotericin B 50 mg Vaginal Suppository, please do not hesitate to contact us. Our team is here to provide you with the information and support you need.

Drug Interactions

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This Amphotericin B 50 mg Vaginal Suppository is a compounded formulation designed for the treatment of various fungal infections of the vagina. These include infections caused by Candida albicans, Candida glabrata, and Candida tropicalis. The formulation is also indicated for the treatment of vulvovaginal candidiasis, vulvovaginal candidiasis refractory to topical antifungal agents, and vulvovaginal candidiasis caused by non-albicans species.

Patients should be aware that this formulation may interact with other medications. These include, but are not limited to, antifungal agents, antibiotics, and anticoagulants. It is crucial for patients to inform their healthcare provider of any medications they are currently taking prior to using this formulation.

Healthcare providers prescribing this formulation should also be aware of potential interactions with other medications. These include antifungal agents, antibiotics, and anticoagulants. Additionally, this formulation may increase the risk of bleeding in patients taking anticoagulants. Therefore, careful monitoring and consideration are required when prescribing this formulation to patients on anticoagulant therapy.

If you have any questions or concerns about the interactions of this formulation, please do not hesitate to reach out for further information.

How Does it Work

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Amphotericin B 50 mg Vaginal Suppository is a potent antifungal medication designed to combat a range of fungal infections. It functions by inhibiting the growth of fungi, thereby preventing the spread of infection. The suppository is inserted into the vagina, where it gradually dissolves, releasing the medication over a period of time. This slow-release mechanism allows for a more consistent distribution of the medication, potentially reducing the risk of side effects.

This suppository is primarily used to treat vaginal yeast infections, but it can also be effective against other fungal infections such as candidiasis and cryptococcal meningitis. It is crucial to follow the instructions provided by your healthcare provider when using this medication. Typically, the suppository is inserted into the vagina once or twice daily, as directed by your doctor or pharmacist. Consistency is key, so it's important to use the suppository at the same time each day to ensure a steady release of the medication.

It's also crucial to complete the full course of treatment, even if symptoms appear to improve. This helps to ensure the complete eradication of the infection and reduces the risk of recurrence. Amphotericin B 50 mg Vaginal Suppository may cause side effects such as burning, itching, or irritation. If you experience any of these symptoms, it's important to consult your healthcare provider immediately.

Before starting this medication, inform your doctor or pharmacist if you are pregnant or breastfeeding. This is to ensure the safety of both you and your baby. If you have any questions or concerns about Amphotericin B 50 mg Vaginal Suppository or its mechanism of action, don't hesitate to reach out to your healthcare provider. They are there to assist you and ensure you receive the most effective treatment for your condition.

Other Uses

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The Amphotericin B 50 mg Vaginal Suppository is a solid dosage form designed for insertion into the vagina, where it dissolves or melts to release the medication. This formulation is primarily used for the treatment of various fungal infections. These include, but are not limited to, Vulvovaginal Candidiasis, Bacterial Vaginosis, Trichomoniasis, Mucocutaneous Candidiasis, and Tinea Versicolor. It is also effective against other fungal infections such as aspergillosis, blastomycosis, and coccidioidomycosis. Furthermore, it has been utilized in the treatment of systemic fungal infections like cryptococcosis, histoplasmosis, and sporotrichosis.

However, it is crucial to note that this formulation is not recommended for use in pregnant women due to potential risks to the fetus. It is also contraindicated in patients with a known hypersensitivity to amphotericin B. Patients using this formulation should be closely monitored for any signs of adverse reactions. These may include fever, chills, nausea, vomiting, or rash. If any of these symptoms occur, patients are advised to contact their healthcare provider immediately. For any further queries regarding the use of this formulation, please consult with a healthcare professional.

Frequently Asked Questions

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What is Amphotericin B 50 mg Vaginal Suppository?

Amphotericin B 50 mg Vaginal Suppository is a solid dosage form of medication that is inserted into the vagina. It dissolves or melts to release the medication for local or systemic absorption.

How does Amphotericin B 50 mg Vaginal Suppository work?

Once inserted into the vagina, the suppository dissolves or melts, releasing the medication. The medication is then absorbed locally or systemically to treat the condition.

What is the purpose of using a suppository form of medication?

Suppositories are used when a medication needs to be absorbed locally in the rectum or vagina, or when oral administration is not suitable. They are also used when a rapid onset of action is required, or when the medication may be destroyed in the digestive tract if taken orally.

How should I store Amphotericin B 50 mg Vaginal Suppository?

Store this medication in a cool, dry place, away from direct heat and light. Keep it out of the reach of children and pets. Do not freeze or refrigerate unless directed by your pharmacist or healthcare provider.

How often should I use Amphotericin B 50 mg Vaginal Suppository?

The frequency of use will depend on your specific medical condition and your healthcare provider's instructions. Always follow the prescribed dosage and never exceed the recommended dose.

What should I do if I miss a dose?

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

What are the potential side effects of Amphotericin B 50 mg Vaginal Suppository?

Side effects may include irritation or burning sensation in the vaginal area. If these persist or worsen, or if you experience severe abdominal pain, fever, or foul-smelling discharge, contact your healthcare provider immediately.

Can I use Amphotericin B 50 mg Vaginal Suppository during my period?

It's best to consult your healthcare provider for specific advice. Some medications can be less effective if used during menstruation, while others may be fine to use.

Can I use other vaginal products while using Amphotericin B 50 mg Vaginal Suppository?

Before starting any new medication, it's important to discuss with your healthcare provider. Some products may interfere with the absorption or effectiveness of Amphotericin B 50 mg Vaginal Suppository.

Is Amphotericin B 50 mg Vaginal Suppository safe to use during pregnancy?

Always consult your healthcare provider before using any medication during pregnancy. The safety of Amphotericin B 50 mg Vaginal Suppository during pregnancy has not been established and should be used only if clearly needed and under medical supervision.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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