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Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche

FDA-approved generic
Dose form
Troches
Active ingredients
Apomorphine Hydrochloride
Sildenafil Citrate

The Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche is a square-shaped solid dosage form that is designed to dissolve slowly in the mouth. This formulation delivers medication through oral mucosa absorption for targeted local or systemic effects. Apomorphine HCl and Sildenafil are combined in this troche to treat specific disease states.

Apomorphine HCl is a dopamine agonist that is used to treat Parkinson's disease symptoms such as stiffness, tremors, muscle spasms, and poor muscle control. Sildenafil is commonly used to treat erectile dysfunction and pulmonary arterial hypertension.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Apomorphine Hydrochloride
Sildenafil Citrate
Troches
653066f9ee7f07e6c2f27824
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation combines Apomorphine HCl 3 mg and Sildenafil 25 mg in an oral troche, a square-shaped solid dosage form designed to dissolve slowly in the mouth. The medication is absorbed through the oral mucosa, allowing for targeted local or systemic effects. This method of administration can provide a rapid onset of action and bypasses the gastrointestinal tract, reducing the potential for gastrointestinal side effects.

Apomorphine HCl is a non-selective dopamine agonist that stimulates dopamine receptors in the brain. It is commonly used to manage motor fluctuations in patients with Parkinson's disease, as it can help to reduce the frequency and severity of 'off' periods - times when the patient's medications are not working well, leading to increased difficulty with movement.

Sildenafil, on the other hand, is a phosphodiesterase type 5 (PDE5) inhibitor. It works by relaxing the muscles and increasing blood flow to particular areas of the body. Sildenafil is most commonly used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH).

The combination of Apomorphine HCl and Sildenafil in this formulation can be used to manage erectile dysfunction, particularly in patients who also have Parkinson's disease. The Apomorphine HCl can help to manage the motor symptoms of Parkinson's disease, while the Sildenafil can help to manage the erectile dysfunction that can be a common problem in these patients. This combination therapy can provide a comprehensive approach to managing these complex patients.

As with any medication, this formulation should be used under the guidance of a healthcare provider. Patients should inform their healthcare provider of all other medications they are taking, as there may be potential interactions. Side effects can include nausea, dizziness, headache, flushing, or stomach upset. If any of these effects persist or worsen, patients should promptly inform their healthcare provider.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to help.

Drug Interactions

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Apomorphine HCl and Sildenafil are both potent medications that can interact with a variety of other drugs. It's crucial to understand these interactions to ensure safe and appropriate use of this formulation.

Apomorphine HCl is a dopamine agonist used primarily for the treatment of Parkinson's disease. It can interact with antipsychotic medications, which may decrease the effectiveness of Apomorphine. It can also interact with antiemetic drugs, leading to a decrease in the anti-Parkinson effects of Apomorphine. Additionally, Apomorphine can interact with alcohol and other CNS depressants, leading to additive sedative effects.

Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor used for the treatment of erectile dysfunction and pulmonary arterial hypertension. It can interact with nitrates, leading to a significant drop in blood pressure. It can also interact with alpha-blockers, which can result in symptomatic hypotension. Other interactions include certain antifungal and antibiotic medications, which can increase the plasma levels of Sildenafil, leading to potential side effects.

When used together in a formulation, Apomorphine and Sildenafil can have additive hypotensive effects. Therefore, it's crucial to monitor blood pressure regularly when using this formulation. Also, the combined use of these two drugs can increase the risk of priapism (prolonged and painful erection), which requires immediate medical attention.

This formulation is designed as an oral troche, which dissolves slowly in the mouth and delivers medication through oral mucosa absorption. This allows for targeted local or systemic effects.

It's important to note that this formulation should be used under the supervision of a healthcare provider. Patients should inform their healthcare provider about all the medications they are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. Our team of compounding pharmacists at Bayview Pharmacy is always here to help.

How Does it Work

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Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche is a unique formulation that combines two potent medications to treat specific disease states. This formulation is designed as a square-shaped solid dosage form that dissolves slowly in the mouth, allowing for the medication to be absorbed through the oral mucosa. This method of delivery can provide targeted local or systemic effects, depending on the specific needs of the patient.

Apomorphine HCl is a non-selective dopamine agonist that works by stimulating dopamine receptors in the brain. This action can help to alleviate symptoms of Parkinson's disease, such as stiffness, tremors, spasms, and poor muscle control. In this formulation, Apomorphine HCl is used for its systemic effects, providing relief from these symptoms throughout the body.

Sildenafil, on the other hand, is a medication commonly used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It works by relaxing the muscles found in the walls of blood vessels and increasing blood flow to particular areas of the body. In the case of ED, Sildenafil increases blood flow to the penis to help achieve and maintain an erection. For PAH, it works by relaxing the blood vessels in the lungs to allow blood to flow more easily.

When combined in this oral troche formulation, Apomorphine HCl and Sildenafil work together to treat both Parkinson's disease symptoms and erectile dysfunction. The slow dissolution of the troche in the mouth allows for a steady absorption of both medications, providing a sustained effect that can be beneficial for patients requiring long-term treatment.

It's important to note that this formulation should be used under the supervision of a healthcare provider, as both Apomorphine HCl and Sildenafil can have side effects and may interact with other medications. Always discuss your medical history and any other medications you are taking with your healthcare provider before starting this treatment.

If you have any questions about this formulation, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Frequently Asked Questions

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What is the Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche?

This is a medication in the form of a square-shaped solid dosage that is meant to dissolve slowly in the mouth. It delivers its therapeutic actions through the oral mucosa, aiming for local or systemic effects.

How should I take the Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche?

You should place the troche in your mouth and let it dissolve slowly. Do not chew or swallow it whole; it is designed to be absorbed through the oral mucosa.

What should I expect when taking this medication?

You can expect the medication to dissolve slowly in your mouth and then be absorbed through the oral mucosa, targeting its therapeutic action either locally or systemically depending on the intended effects of your prescription.

What are the benefits of taking a compounded formulation like Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche?

Compounded formulations are created to meet specific patient needs that mass-produced medications may not address. This formulation allows for the combination of Apomorphine and Sildenafil in a way that facilitates targeted local or systemic effects.

Can I just swallow the Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche like a normal pill?

No, it is designed to dissolve slowly in the mouth for absorption through the oral mucosa. Swallowing it whole may not yield the intended therapeutic effects.

How long does it take for the oral troche to dissolve in the mouth?

The dissolving time may vary depending on individual factors but generally, the troche should dissolve slowly in your mouth for a more extended release of the medication.

Will the Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche cause any side effects?

Like all medications, this compounded formulation can have side effects. It's vital to discuss potential side effects with your healthcare provider before starting the medication.

Why are these medications combined in this form?

Both Apomorphine and Sildenafil have distinct therapeutic properties that can complement each other in managing some health conditions. Their combined use in this formulation aims to leverage these benefits in a single dosage.

Is the Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche safe to use?

This medication is generally safe when used as prescribed by your healthcare provider. It's important to provide your healthcare provider with a full medical history before starting this or any medication.

How often should I take the Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche?

The dosing regimen should be determined by your healthcare provider based on your specific needs and conditions. Follow their instructions for how often and when to use this medication.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Apomorphine HCl 3 mg/Sildenafil 25 mg Oral Troche
Troches
90 troches
controlled

Place 1 troche between cheek and gum and let slowly dissolve

Once daily as needed