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Atropine Sulfate 7.8 mcg/Hyoscyamine Sulfate 41.5 mcg/Scopolamine HBr 2.6 mcg/mL Oral Liquid

This formulation is a specially prepared oral liquid medication containing Atropine Sulfate 7.8 mcg, Hyoscyamine Sulfate 41.5 mcg, and Scopolamine HBr 2.6 mcg per mL. It is designed for easy ingestion and precise delivery of medication, making it an ideal choice for individuals who find it difficult to swallow solid dosage forms, as well as for pediatric and geriatric patients.

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Oral Liquid
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Formula Information

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This formulation is a compounded oral liquid medication containing Atropine Sulfate 7.8 mcg, Hyoscyamine Sulfate 41.5 mcg, and Scopolamine HBr 2.6 mcg per mL. It is specifically designed to provide a convenient and easily ingested dosage form for accurate delivery of medication. This formulation is often used when swallowing solid dosage forms is challenging, such as in pediatric and geriatric populations.

Atropine Sulfate, Hyoscyamine Sulfate, and Scopolamine HBr are anticholinergic agents that work by blocking the action of acetylcholine, a neurotransmitter in the body. This action helps to decrease the production of body fluids, slow the natural movements of the gut, and increase the relaxation of smooth muscles.

These medications are commonly used to treat a variety of conditions such as gastrointestinal disorders like irritable bowel syndrome, peptic ulcers, and diverticulitis. They can also be used to treat certain bladder conditions, reduce secretions in the mouth, throat, airway, and stomach before surgery, and to control symptoms associated with Parkinson's disease.

It's important to note that this medication should be used under the supervision of a healthcare provider, as it may cause side effects such as dry mouth, blurred vision, constipation, drowsiness, and confusion. Patients should also be aware that this medication may cause dizziness and impair their ability to drive or operate machinery.

Prescribers should consider the patient's overall health status, other medications being taken, and the specific disease state being treated when deciding on the appropriate dosage and frequency of this medication. Regular monitoring and follow-up are necessary to ensure the medication is working effectively and to manage any potential side effects.

If you have any questions about this formulation or its use in treating specific disease states, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This formulation, a combination of Atropine Sulfate, Hyoscyamine Sulfate, and Scopolamine HBr, is primarily used to treat gastrointestinal disorders such as irritable bowel syndrome and ulcers. These medications work by reducing the production of stomach acid and slowing the natural movements of the gut. This helps to relieve symptoms such as stomach cramps, abdominal pain, and diarrhea.

However, it's important to be aware of potential drug interactions. Atropine Sulfate, Hyoscyamine Sulfate, and Scopolamine HBr can interact with several other medications, potentially altering their effects or increasing the risk of side effects.

These medications may interact with antihistamines, tricyclic antidepressants, or other drugs that have anticholinergic effects. This can increase the risk of side effects such as dry mouth, blurred vision, and urinary retention. If you are taking any of these medications, it's important to discuss this with your healthcare provider.

Additionally, these medications can interact with certain heart medications, including digoxin and quinidine. This can potentially lead to an irregular heartbeat or other heart-related side effects. If you are taking any heart medications, it's crucial to inform your healthcare provider.

These medications may also interact with certain antifungal medications, such as ketoconazole, potentially reducing their effectiveness. If you are taking an antifungal medication, it's important to discuss this with your healthcare provider.

Furthermore, these medications can interact with certain drugs used for Parkinson's disease, such as levodopa, potentially reducing their effectiveness. If you are taking a medication for Parkinson's disease, it's crucial to inform your healthcare provider.

It's also important to note that these medications can interact with alcohol, potentially increasing the risk of side effects such as drowsiness and dizziness. It's generally recommended to avoid or limit alcohol consumption while taking these medications.

Remember, this is not a complete list of potential drug interactions. Always inform your healthcare provider of all the medications, supplements, and herbal products you are currently taking to ensure this medication is safe for you.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

How Does it Work

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This formulation is a combination of three active ingredients: Atropine Sulfate, Hyoscyamine Sulfate, and Scopolamine Hydrobromide. Each of these components plays a crucial role in the treatment of various disease states.

Atropine Sulfate works by blocking the action of acetylcholine, a neurotransmitter in the body. Acetylcholine is involved in transmitting signals in the body that control functions such as heart rate, salivation, pupil dilation, urination, and digestion. By blocking the action of acetylcholine, Atropine Sulfate can help to control symptoms such as excessive salivation and secretions, and slow heart rate.

Hyoscyamine Sulfate also works by blocking the action of acetylcholine. It is particularly effective in the treatment of gastrointestinal disorders such as irritable bowel syndrome and ulcers. It works by reducing the production of stomach acid and slowing the movements of the intestines, which can help to reduce symptoms such as stomach pain, bloating, and diarrhea.

Scopolamine Hydrobromide is another anticholinergic medication that works by blocking the action of acetylcholine. It is often used to treat motion sickness and post-operative nausea and vomiting. It works by reducing the activity of the nerve fibers in the inner ear that trigger nausea and vomiting.

This formulation is provided in a liquid form for oral administration, which makes it a convenient and easily ingested dosage form. This is particularly useful for patients who have difficulty swallowing solid dosage forms, such as children and the elderly. The liquid form also allows for accurate dosing, which is crucial for the effective treatment of the disease states mentioned above.

It's important to note that while this formulation can be highly effective in treating these conditions, it may not be suitable for everyone. Patients with certain conditions such as glaucoma, myasthenia gravis, or certain heart conditions may not be able to take this medication. Additionally, it may interact with other medications, so it's important to discuss all medications and supplements you are currently taking with your healthcare provider.

If you have any questions about this formulation, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This formulation of Atropine Sulfate, Hyoscyamine Sulfate, and Scopolamine HBr is not just limited to the indicated uses licenced by the FDA, but may also be employed off-label in some other situations under the guidance and discretion of the healthcare provider. Containing anticholinergic agents, this oral liquid can be used to address gastrointestinal disorders such as irritable bowel syndrome (IBS) and enterocolitis by reducing spasms and gastric secretions, thereby alleviating associated symptoms such as cramping, stomach discomfort, and diarrhea.

In the field of ophthalmology, this formulation could be utilized as an adjunctive therapy for uveitis by reducing the inflammation and pain associated with the condition, thanks to the mydriatic and cycloplegic properties of atropine sulfate and the antispasmodic effects of hyoscyamine sulfate. However, this use would typically involve ophthalmic preparation and needs to be monitored carefully due to potential side effects.

In addition, Atropine Sulfate, Hyoscyamine Sulfate, and Scopolamine HBr oral liquid may be prescribed to manage the symptoms of various respiratory diseases characterized by bronchospasms like COPD (Chronic Obstructive Pulmonary Disease), asthma or cystic fibrosis. The anticholinergic properties of the formulation can help to relax and widen the airways, making breathing easier.

Lastly, in the palliative care setting, the medicine may be applied as a sialagogue to reduce drooling or excess salivation in patients with neurodegenerative conditions such as Parkinson's disease and ALS (Amyotrophic Lateral Sclerosis) or those who have had a stroke. This is primarily due to scopolamine's ability to inhibit salivation.

Please note that any off-label use of medications should only be done under the direct supervision and consent of a healthcare provider, who thoroughly understands the potential benefits and risks, as well as the patient's medical history and other concurrent medications. It's important to communicate clearly with your healthcare provider to ensure optimal treatment outcomes.

If you have further inquiries or questions about the other uses of this formulation, please do not hesitate to get in touch with us at Bayview Pharmacy. We are always ready to assist you.

Frequently Asked Questions

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What is this compounded formulation used for?

This medication is used for a variety of conditions that may require treatment with antispasmodic or anticholinergic agents. Its three active ingredients: Atropine Sulfate, Hyoscyamine Sulfate, and Scopolamine HBr, work in synergy to help manage symptoms such as spasms in the stomach, intestines, and bladder.

What forms does this medication come in?

This medication comes in the form of a liquid intended for oral administration, which is easier to ingest compared to solid dosage forms. This form is especially suitable for individuals who have difficulty swallowing solid dosage forms, like children and older adults.

How should this medication be stored?

This medication should be stored in a cool, dry place away from light and out of reach of children. Refer to the specific instructions on your prescription label or ask your pharmacist for more detailed storage directions if unsure.

How should this medication be taken?

Take this medication exactly as prescribed by your healthcare provider. The exact dose will vary depending on your specific medical condition and response to treatment.

What are the potential side effects of this medication?

Side effects can vary for each individual and can include dry mouth, blurred vision, dizziness, or confusion. If any of these side effects persist or worsen, you should immediately consult your healthcare provider.

What should I do if I miss a dose?

If you miss a dose, you should take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue on your regular schedule. Do not double doses.

Who should not take this medication?

Patients with specific conditions such as glaucoma, myasthenia gravis, or obstructive uropathy, among others, may not be suitable candidates for this medication. Always consult your healthcare provider before starting a new medication.

Can this medication be taken with other medications?

Interactions may occur when this medication is taken with others. Ensure to notify your healthcare provider about all medications and health products you use, including prescription, over-the-counter, and herbal products, to properly manage potential interactions.

Can pregnant or breastfeeding women take this medication?

If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your healthcare provider to evaluate the potential benefits and risks before starting this medication.

Should I be concerned about allergies with this medication?

If you have had a previous allergic reaction to any of the active ingredients in this medication, or if you have any other allergies, let your healthcare provider know. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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