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Formulas

Azithromycin 75 mg Rectal Suppository

FDA-approved generic
Dose form
Suppository
Active ingredients
Azithromycin

The Azithromycin 75 mg Rectal Suppository is a solid dosage form designed for insertion into the rectum. Upon insertion, the suppository dissolves or melts, releasing the antibiotic Azithromycin for local or systemic absorption. This formulation is typically used to treat a variety of bacterial infections, including those affecting the respiratory system, skin, ears, and sexually transmitted diseases. The rectal administration route allows for direct, localized treatment, potentially reducing systemic side effects.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Azithromycin
Suppository
653157d14a3c0a7060548981
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Azithromycin 75 mg Rectal Suppository is a specialized formulation designed for administration via the rectal route. This solid dosage form is inserted into the rectum, where it dissolves or melts, releasing the medication for local or systemic absorption.

Azithromycin works by inhibiting the growth of bacteria by interfering with their protein synthesis. It binds to the 50S subunit of the bacterial ribosome, thus inhibiting translation of mRNA. This action prevents the bacteria from growing, and its further reproduction is halted, leading to the eventual elimination of the bacterial infection from the body.

This formulation is particularly useful in treating various bacterial infections, including respiratory infections, skin infections, ear infections, and sexually transmitted diseases. It can also be used in patients who have difficulty swallowing oral medication or for whom intravenous administration is not suitable. The rectal route of administration allows for the medication to be absorbed directly into the bloodstream, bypassing the digestive system, which can lead to a faster onset of action and potentially fewer gastrointestinal side effects.

Patients using this formulation should follow the instructions provided by their healthcare provider. The suppository should be inserted into the rectum as directed, and hygiene practices should be followed to prevent the spread of infection. It's important to complete the full course of treatment, even if symptoms improve before the medication is finished, to ensure the complete eradication of the bacteria and prevent resistance.

Prescribers should consider the patient's overall health status, other medications, and potential drug interactions when prescribing this formulation. Azithromycin is generally well-tolerated, but side effects can occur, including stomach upset, diarrhea, and allergic reactions. Patients should be monitored for these and other potential side effects.

If you have any questions about the Azithromycin 75 mg Rectal Suppository formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide the information and support you need to ensure optimal treatment outcomes.

Drug Interactions

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Azithromycin is a macrolide antibiotic that works by stopping the growth of bacteria. This medication is used to treat a variety of bacterial infections, including sexually transmitted infections, respiratory infections, skin infections, ear infections, and others.

When considering the use of Azithromycin 75 mg Rectal Suppository, it is crucial to be aware of potential drug interactions. Drug interactions can change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: live bacterial vaccines, antacids containing aluminum or magnesium, other antibiotics (such as erythromycin, telithromycin), warfarin, digoxin, and drugs that prolong the QT interval (including certain antipsychotic medications, certain antidepressants, and drugs for irregular heart rhythms).

Azithromycin can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include some drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), certain drugs to treat seizures (such as carbamazepine, phenytoin), among others.

Although most antibiotics are unlikely to affect hormonal birth control such as pills, patch, or ring, some antibiotics (such as rifampin, rifabutin) can decrease their effectiveness. This could result in pregnancy. If you use hormonal birth control, ask your doctor or pharmacist for more details.

It is also important to note that azithromycin should not be used with any other medication containing azithromycin or erythromycin. Using these medications together can increase the risk of certain side effects and can potentially lead to a life-threatening irregular heart rhythm.

Remember that your healthcare provider has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

If you have any questions or concerns about Azithromycin 75 mg Rectal Suppository, or its potential interactions with other medications, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

How Does it Work

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Azithromycin 75 mg Rectal Suppository is a solid dosage form that is inserted into the rectum where it dissolves or melts to release the medication. The active ingredient in this formulation is Azithromycin, a macrolide-type antibiotic. This antibiotic works by stopping the growth of bacteria.

Once the suppository is inserted into the rectum, it begins to dissolve due to the body's natural heat. As it dissolves, the Azithromycin is released and absorbed into the bloodstream through the rectal tissue. This allows the medication to circulate throughout the body and target the bacteria causing the infection.

Azithromycin works by binding to the 50S subunit of the bacterial ribosome, thus inhibiting protein synthesis in susceptible bacteria. It interferes with microbial protein synthesis by binding to the 50S ribosomal subunit. This action prevents bacteria from growing, which leads to their eventual elimination from the body.

Rectal administration of Azithromycin can be beneficial in cases where oral administration is not possible or not recommended. This could be due to nausea, vomiting, difficulty swallowing, or specific drug-drug interactions. Furthermore, rectal administration can provide a more direct route for the medication to enter the bloodstream, potentially allowing for quicker onset of action.

It's important to note that Azithromycin only works against bacterial infections. It will not work for viral infections (such as common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

As with any medication, it's crucial to use Azithromycin Rectal Suppositories as directed by your healthcare provider. The dosage is based on your medical condition and response to treatment. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and the risk of serious side effects may increase.

If you have any questions about Azithromycin 75 mg Rectal Suppositories or would like more information, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Frequently Asked Questions

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What is this compounded formulation of Azithromycin 75 mg Rectal Suppository?

It is a solid dosage form of the medication, azithromycin, that is inserted into a body cavity, usually the rectum, where it dissolves or melts to release the medication. The absorbed medication helps in treating certain infections and diseases.

How does a rectal suppository work?

A rectal suppository works by being inserted into the rectum where it dissolves or melts. Once dissolved, the medication is absorbed by the body, either for a localized effect in the rectal area or for a systemic effect throughout the body.

What is the purpose of using a rectal suppository?

Rectal suppositories are used when a fast or localized medication delivery method is preferred.

Why is Azithromycin used in this form?

Azithromycin is used in this form to provide a controlled, slow release of medication in the body. This ensures that the medication's effective levels are maintained for a longer period. Also, in cases where oral administration is not possible, this formulation can be used.

What conditions can be treated with this form of Azithromycin?

This form of Azithromycin can be used to treat various bacterial infections. Azithromycin is a broad-spectrum antibiotic, so it covers a wide range of bacterial infections.

Are there any side effects of this medication?

As with any medication, there could be some side effects. Common side effects may include stomach pain, mild diarrhea or rectal discomfort. If you experience severe or persistent side effects, contact your healthcare provider immediately.

What is the proper way to administer this suppository?

The suppository should be gently inserted into the rectum, being careful not to force it. You are advised to lie on your side during administration for easier insertion and better absorption.

How often should I use this suppository?

The frequency of use will depend on the specific medical condition being treated and your individual response to treatment. Always follow your healthcare provider’s instructions regarding dosage and frequency.

Are there any storage requirements for this medication?

This medication should be stored in a cool, dry place, away from direct sunlight and heat sources. Always keep it out of reach of children and pets.

What should I do in case of a missed dose?

If you miss a dose, administer it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Azithromycin 75 mg Rectal Suppository
Suppository
30 suppositories
controlled

Insert 1 unwrapped suppository

Once daily