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Benzoyl Peroxide 5%/Clindamycin 1%/Tretinoin 0.01% Topical Lotion

This formulation is a topical lotion containing Benzoyl Peroxide 5%, Clindamycin 1%, and Tretinoin 0.01%. It is a liquid or semi-liquid preparation designed for external application to the skin. The lotion provides a smooth and spreadable consistency, offering moisturizing, soothing, or therapeutic effects for specific skin conditions. It promotes the absorption of the active ingredients for localized treatment.

The active ingredients in this formulation work synergistically to treat various skin conditions. Benzoyl Peroxide is an antimicrobial agent that reduces inflammation and clears pores. Clindamycin is an antibiotic that stops the growth of bacteria that cause acne. Tretinoin, a form of vitamin A, helps to renew the skin.

It can also be used to treat rosacea, a chronic skin disease that causes redness and swelling. Additionally, it can be used for the treatment of keratosis pilaris, a condition that causes rough patches and small, acne-like bumps on the skin.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.

Prescriber? Sign in or create an account for prescription details and order forms.

Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Benzoyl Peroxide
Tretinoin
Clindamycin Hydrochloride
Topical Lotion
6535cdd510213a8348f825c3

Formula Information

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This formulation combines three active ingredients: Benzoyl Peroxide 5%, Clindamycin 1%, and Tretinoin 0.01% in a topical lotion form. Each of these ingredients plays a crucial role in treating various skin conditions. The lotion is designed for external application to the skin, providing a smooth and spreadable consistency. It offers moisturizing, soothing, or therapeutic effects for specific skin conditions, while promoting absorption of active ingredients for localized treatment.

Benzoyl Peroxide is a potent antimicrobial agent that works by releasing oxygen to kill P. acnes bacteria, the primary cause of acne. It also helps to remove excess oil and dead skin cells that can clog pores. Clindamycin is an antibiotic that stops the growth of bacteria that cause acne. It reduces swelling and redness and helps prevent acne scars. Tretinoin, a derivative of Vitamin A, promotes skin cell turnover and prevents the plugging of hair follicles, which can lead to acne. It also helps to reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.

This formulation is typically used to treat acne vulgaris, a common skin condition characterized by blackheads, whiteheads, and pimples. It may also be used to treat other skin conditions as determined by a healthcare provider. The combination of these three active ingredients provides a comprehensive approach to acne treatment, targeting the bacteria that cause acne, reducing inflammation, and promoting skin cell turnover to prevent clogged pores.

Patients should apply this lotion to the affected area once a day, or as directed by a healthcare provider. It's important to use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day. Do not use more of this medication than prescribed or use it more often, as your condition will not improve faster and your risk of side effects may increase.

Side effects may include skin dryness, burning, redness, or peeling. If these effects persist or worsen, notify your doctor or pharmacist promptly. It's important to note that this medication may make you more sensitive to the sun. Limit your time in the sun and avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.

For prescribers, it's important to note that this formulation should not be used in patients with a history of hypersensitivity to any of its ingredients. It should also be used with caution in pregnant or breastfeeding women, as tretinoin is known to cause birth defects.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Drug Interactions

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This formulation combines three active ingredients: Benzoyl Peroxide, Clindamycin, and Tretinoin. Each of these ingredients has a unique mechanism of action and potential for drug interactions.

It works by reducing the amount of acne-causing bacteria on the skin and by causing the skin to dry and peel. It is generally well-tolerated, but it can interact with certain other topical medications, particularly those that are abrasive, irritating, or drying to the skin. Concurrent use with these types of medications may increase the risk of excessive skin irritation.

Clindamycin is a topical antibiotic that is used to treat bacterial infections of the skin. It works by stopping the growth of bacteria. It can interact with other antibiotics, particularly those that work by the same mechanism, potentially leading to antibiotic resistance. It can also interact with certain oral medications, such as erythromycin, which may decrease its effectiveness.

Tretinoin is a form of vitamin A that helps the skin renew itself. It is used to treat acne and reduce the appearance of fine wrinkles and mottled skin discoloration. Tretinoin can interact with other topical medications, particularly those that are abrasive, irritating, or drying to the skin. Concurrent use with these types of medications may increase the risk of excessive skin irritation. It can also interact with certain oral medications, such as tetracyclines, which can increase the risk of increased intracranial pressure.

It's important to note that while these potential interactions are possible, they are not guaranteed to occur in every individual. Factors such as the individual's overall health, other medications they are taking, and their specific skin condition can all influence the likelihood of an interaction occurring.

This formulation is designed to treat acne, a common skin condition that causes pimples, blackheads, and whiteheads. The combination of Benzoyl Peroxide, Clindamycin, and Tretinoin works to reduce the amount of acne-causing bacteria on the skin, stop the growth of these bacteria, and help the skin renew itself. This can help to reduce the number of acne breakouts and promote clearer, healthier skin.

If you have any questions about this formulation or its potential interactions with other medications, please don't hesitate to reach out to us. We are here to help ensure that you are using this medication safely and effectively.

How Does it Work

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The Benzoyl Peroxide 5%/Clindamycin 1%/Tretinoin 0.01% Topical Lotion is a specially formulated treatment designed to combat a variety of skin conditions, including acne. This formulation combines the antibacterial, anti-inflammatory, and comedolytic properties of its active ingredients to provide a comprehensive approach to skin care.

Benzoyl Peroxide is a potent antimicrobial agent that works by introducing oxygen into the pores, which kills the bacteria (P. acnes) responsible for acne. This bacteria cannot survive in an oxygen-rich environment, thus benzoyl peroxide effectively reduces the bacterial count on the skin surface, reducing inflammation and the formation of acne lesions.

Clindamycin, an antibiotic, works by inhibiting the synthesis of essential proteins needed by bacteria to carry out vital functions. This stops the growth of bacteria associated with acne, further reducing inflammation and preventing the spread of infection.

Tretinoin, a derivative of Vitamin A, promotes the turnover of skin cells, preventing the clogging of pores. It also reduces the cohesiveness of follicular epithelial cells resulting in decreased microcomedone formation. This helps to keep the skin's surface smooth and reduces the formation of acne lesions.

The lotion base of this formulation is designed to promote the absorption of these active ingredients into the skin, while also providing a moisturizing effect. This helps to soothe the skin and reduce any potential irritation caused by the active ingredients. The lotion is easily spreadable, allowing for even application over the affected area.

This formulation is typically used in the treatment of acne vulgaris, but may also be beneficial in other conditions characterized by inflammation and/or bacterial infection of the skin. It is important to note that while this formulation can significantly improve these conditions, it may not completely cure them. Regular and consistent use as directed by a healthcare provider is necessary for optimal results.

If you have any questions about this formulation, its use, or if it is the right treatment for your specific condition, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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Benzoyl Peroxide 5%/Clindamycin 1%/Tretinoin 0.01% Topical Lotion is primarily used for the treatment of mild to moderate acne. This combination of active ingredients works to reduce the proliferation of acne bacteria, unclog pores and reduce inflammation which are all contributing factors to acne.

Other than that, this formulation may also be used to treat rosacea, a skin condition that results in redness and often small, red, pus-filled bumps on the face. The anti-inflammatory properties of both Clindamycin and Benzoyl Peroxide can reduce the redness associated with rosacea, while Tretinoin promotes the renewal of skin cells. However, care should be exercised if using this product for rosacea since skin can become more sensitive to sun exposure, making the condition potentially worse.

Additionally, this lotion may be used to treat folliculitis, a condition that results in the inflammation of one or more hair follicles. The antibacterial nature of Clindamycin partnered with the exfoliating effects of Tretinoin can potentially prevent hair follicle inflammation. It's important to note though, that topical creams aren't typically the first line of treatment for this condition and should be utilized under the guidance of a healthcare professional.

Occasionally, under the guidance of a healthcare professional, this compound may be used for off-label uses, especially for skin conditions that involve bacterial infection and/or inflammation. Always consider the potential side effects and increased sensitivity to sunlight when using this product. Avoid eye and mouth areas to prevent potential irritation.

Please note that while we aim to provide accurate information, this does not substitute or replace professional medical advice. Always consult your healthcare provider before starting any new medications or treatments. For any questions or concerns related to this formulation, please feel free to contact us at Bayview Pharmacy.

Frequently Asked Questions

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What is the Benzoyl Peroxide 5%/Clindamycin 1%/Tretinoin 0.01% Topical Lotion?

This is a skin lotion compounded with the active ingredients Benzoyl Peroxide, Clindamycin, and Tretinoin. It's designed for external use on the skin to treat specific skin conditions by promoting absorption of its active ingredients.

What does this lotion do?

This lotion delivers moisture, therapeutic effects, and relief for specific skin conditions. It also effectively delivers the active ingredients Benzoyl Peroxide, Clindamycin, and Tretinoin to the localized skin area.

Is this lotion applicable for all skin types?

Generally, the lotion is designed for a wide range of skin types. However, it's always recommended to test a small amount of the lotion on your skin first before fully applying. If you have any known allergies or sensitivities to the active ingredients, consult your healthcare provider before starting the use of this lotion.

How is the texture of the Benzoyl Peroxide 5%/Clindamycin 1%/Tretinoin 0.01% Topical Lotion?

The lotion is a liquid or semi-liquid formulation that provides a smooth and easily spreadable consistency on the skin. This facilitates greater absorption of its active ingredients.

Can this lotion be used daily?

Typically, this lotion can be used daily. Though, the frequency will depend on your skin type and the specific skin condition being treated. Always follow your healthcare provider's instructions.

Can this lotion be used in combination with other skincare products?

Generally, this depends on the type of skincare product and the active ingredients it contains. Before combining with other products, consult your healthcare provider to avoid potential adverse reactions.

Can I use this lotion if I'm pregnant or breastfeeding?

If you're pregnant or breastfeeding, consult your healthcare provider before using this lotion because it contains medicated ingredients that can potentially affect the baby.

Are there any side effects associated with the use of this lotion?

Like any medicated product, potential side effects can occur. These include but are not limited to dryness, peeling, redness, sometimes burning sensation, etc. If you experience severe side effects, discontinue use and consult your healthcare provider.

Does this lotion have a specific storage requirement?

Generally, keep this lotion in a cool, dry place away from direct sunlight and heat. However, always check the packaging for specific storage instructions.

Do I need a prescription for this lotion?

Yes, as this lotion contains medicated ingredients, a prescription from a certified healthcare provider will typically be necessary.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Benzoyl Peroxide 5%/Clindamycin 1%/Tretinoin 0.01% Topical Lotion
Topical Lotion
30 g
controlled

Apply topically to affected area(s)