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Buprenorphine 0.3% Nasal Spray

FDA-approved generic
Dose form
Nasal Spray
Active ingredients
Buprenorphine Hydrochloride

Buprenorphine 0.3% Nasal Spray is a compounded liquid formulation, specifically designed for nasal administration. It is used in the treatment of opioid dependence, chronic pain, anxiety, depression, and insomnia. This medication is available at Bayview Pharmacy.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Buprenorphine Hydrochloride
Nasal Spray
6427079ea64324a0d35187b4

Formula Information

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Buprenorphine 0.3% Nasal Spray is a unique compounded formulation of buprenorphine, an opioid agonist, specifically designed to treat moderate to severe pain. This innovative formulation is delivered in a liquid spray form, intended for administration directly into the nasal cavity. The nasal delivery method allows for targeted local or systemic effects through the nostrils, providing rapid and long-lasting relief from pain symptoms.

Additionally, it is also indicated for the treatment of opioid dependence in adults, offering a dual benefit for those struggling with both pain and addiction.

The mechanism of action of Buprenorphine 0.3% Nasal Spray involves binding to opioid receptors in the brain. This action not only provides relief from pain but also reduces cravings for opioids. The formulation is fast-acting, with effects typically seen within minutes of administration. Furthermore, the effects of the spray can last up to 8 hours, offering sustained relief from pain and opioid cravings.

Buprenorphine 0.3% Nasal Spray is a appropriate treatment option for patients suffering from moderate to severe pain and opioid dependence. However, it is crucial to remember that this formulation should only be used under the direction of a healthcare provider. If you have any questions or concerns about this formulation, please do not hesitate to contact us at Bayview Pharmacy. We are committed to providing comprehensive information and support to ensure the safe and appropriate use of our compounded formulations.

Drug Interactions

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Buprenorphine 0.3% Nasal Spray is a compounded formulation specifically designed for the treatment of opioid dependence. This liquid formulation is delivered in a spray form for administration into the nasal cavity, providing targeted local or systemic effects through the nostrils. It functions by blocking the effects of opioids, thereby reducing cravings and withdrawal symptoms associated with opioid dependence.

It is crucial to understand that Buprenorphine 0.3% Nasal Spray is not a substitute for other opioids and is not intended to treat pain. Instead, it should be used as part of a comprehensive treatment plan that includes counseling and psychosocial support to effectively manage opioid dependence.

Patients using Buprenorphine 0.3% Nasal Spray should be closely monitored for signs of misuse, abuse, or addiction. It is also advised that patients avoid the consumption of alcohol and other Central Nervous System (CNS) depressants while undergoing treatment with this medication, as it may lead to adverse effects.

Furthermore, Buprenorphine 0.3% Nasal Spray may interact with other medications, including but not limited to benzodiazepines, alcohol, and other opioids. Therefore, patients should be encouraged to disclose all medications they are currently taking to their healthcare provider to avoid potential drug interactions.

If you have any questions or concerns regarding the use of Buprenorphine 0.3% Nasal Spray, please do not hesitate to reach out to your healthcare provider for further information and guidance.

How Does it Work

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Buprenorphine 0.3% Nasal Spray is a specialized medication designed to aid in the treatment of opioid dependence and opioid use disorder. This unique formulation works by binding to the same receptors in the brain as opioids, but with a significantly reduced risk of abuse and addiction. The nasal spray is administered directly into the nasal cavity, where it is rapidly absorbed into the bloodstream, providing targeted local or systemic effects.

The active ingredient in this nasal spray is buprenorphine, a partial opioid agonist. This means it interacts with the same receptors in the brain as opioids, but with a much lower potential for abuse and addiction. The nasal spray is available in a 0.3% concentration, which is the highest concentration available for this formulation, ensuring maximum efficacy.

Buprenorphine 0.3% Nasal Spray is primarily used in the treatment of opioid dependence and opioid use disorder. It functions by blocking the effects of opioids, thereby reducing cravings and withdrawal symptoms, and aiding in the prevention of relapse. This medication is typically used in conjunction with counseling and other therapeutic interventions to support patients on their journey towards long-term recovery.

When using Buprenorphine 0.3% Nasal Spray, it is crucial to adhere to the instructions provided by your healthcare provider. The dosage and frequency of administration will be tailored to the individual patient and their specific needs. It is essential to use the medication as prescribed and not to alter the dosage without consulting your healthcare provider.

If you have any queries about Buprenorphine 0.3% Nasal Spray or its mechanism of action, do not hesitate to seek clarification. Understanding your medication and how it contributes to your recovery process is a vital step towards achieving long-term recovery.

Other Uses

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Buprenorphine 0.3% Nasal Spray is a compounded formulation designed to alleviate opioid withdrawal symptoms such as nausea, vomiting, and diarrhea. This liquid formulation, delivered in a spray form, is administered into the nasal cavity, providing targeted local or systemic effects. It is also utilized to diminish cravings for opioids, thereby aiding in the prevention of relapse.

Aside from its primary use, Buprenorphine 0.3% Nasal Spray has been employed off-label to manage a range of conditions including anxiety, depression, and insomnia. It has demonstrated efficacy in reducing symptoms of anxiety and depression, as well as enhancing sleep quality. However, it is crucial to understand that buprenorphine is not a replacement for conventional treatments for these conditions, such as psychotherapy or other medications.

While Buprenorphine 0.3% Nasal Spray has shown promise in these areas, it is essential to consult with a healthcare professional before using it for any of these conditions. Always seek professional advice to ensure the safe and appropriate use of this medication.

Frequently Asked Questions

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What is Buprenorphine 0.3% Nasal Spray?

Buprenorphine 0.3% Nasal Spray is a liquid formulation that is delivered in a spray form. It is specifically designed for administration into the nasal cavity, providing targeted local or systemic effects through the nostrils.

How does Buprenorphine 0.3% Nasal Spray work?

The spray works by delivering the medication directly into the nasal cavity. This allows for a targeted local or systemic effect, depending on the specific needs of the patient.

How should I use Buprenorphine 0.3% Nasal Spray?

The spray should be administered as directed by your healthcare provider. It is typically sprayed into the nostrils for the desired effect.

What are the potential side effects of Buprenorphine 0.3% Nasal Spray?

As with any medication, there can be potential side effects. These can vary from person to person and may include nasal irritation, dryness, or discomfort. Always consult with your healthcare provider for a complete list of potential side effects.

Can I use Buprenorphine 0.3% Nasal Spray if I have a cold or nasal congestion?

It's important to consult with your healthcare provider if you have a cold or nasal congestion. They can provide guidance on whether it's safe to use the nasal spray under these conditions.

Is Buprenorphine 0.3% Nasal Spray safe for children?

The safety and effectiveness of Buprenorphine 0.3% Nasal Spray in children has not been established. Always consult with a healthcare provider before administering any medication to a child.

Can I use Buprenorphine 0.3% Nasal Spray while pregnant or breastfeeding?

It's important to consult with your healthcare provider if you are pregnant or breastfeeding. They can provide guidance on whether it's safe to use the nasal spray during this time.

What should I do if I miss a dose of Buprenorphine 0.3% Nasal Spray?

If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Can I use Buprenorphine 0.3% Nasal Spray with other medications?

It's important to discuss all medications you are currently taking with your healthcare provider before starting Buprenorphine 0.3% Nasal Spray. This includes prescription medications, over-the-counter drugs, and herbal supplements.

How should I store Buprenorphine 0.3% Nasal Spray?

Store the nasal spray at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Buprenorphine 0.3% Nasal Spray
Nasal Spray
10 mL
controlled

Inhale intranasally