Sublingual Semaglutide and Tirzepatide are now available! Learn More

Caffeine 100 mg/Promethazine HCl 50 mg/Dihydroergotamine Mesylate 5 mg Suppository

Bayview Pharmacy's Caffeine 100 mg/Promethazine HCl 50 mg/Dihydroergotamine Mesylate 5 mg Suppository is a compounded medication. This solid dosage form is inserted into a body cavity, where it dissolves or melts to release the medication. It is typically used for the treatment of various types of headaches including migraines, cluster headaches, menstrual migraines, post-traumatic headaches, and tension headaches.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Are you a prescriber? Sign Up
Trusted by 55,278 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Suppository
6427079ea6432488dc5187d3
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

This compounded formulation of Caffeine 100 mg/Promethazine HCl 50 mg/Dihydroergotamine Mesylate 5 mg Suppository is a potent treatment for various headache disorders, including Migraine, Cluster Headache, Menstrual Migraine, Post-Traumatic Headache, and Tension Headache. The combination of these three active ingredients, each with a unique mechanism of action, provides a comprehensive approach to headache management.

Caffeine, a stimulant, works by reducing the severity of headaches. Promethazine HCl, an antihistamine, aids in reducing inflammation and pain. Dihydroergotamine Mesylate, an ergot alkaloid, contributes to reducing the frequency and intensity of headaches. This combination of medications can be used both as a preventative measure and as an acute treatment, making it a versatile option for patients suffering from various types of headaches.

The suppository form of this formulation is designed for easy administration and is typically well tolerated by most patients. It is a solid dosage form that is inserted into a body cavity, usually the rectum or vagina, where it dissolves or melts to release the medication for local or systemic absorption. This method of administration allows for the medication to be absorbed directly into the bloodstream, bypassing the digestive system and providing faster relief.

However, it is crucial to note that this formulation should not be used in patients with a history of cardiovascular disease, as it may increase the risk of adverse events. Potential side effects to monitor include nausea, dizziness, or drowsiness. Always consult with a healthcare professional before starting any new medication regimen.

If you have any questions about this formulation or how it can be used to treat headache disorders, please do not hesitate to contact us at Bayview Pharmacy. Our team of compounding pharmacists is equipped with the knowledge and expertise to assist you with your medication needs.

Drug Interactions

A small arrow pointing down

This compounded formulation of Caffeine 100 mg/Promethazine HCl 50 mg/Dihydroergotamine Mesylate 5 mg Suppository is specifically designed to provide relief from various types of headaches including migraines, cluster headaches, menstrual migraines, post-traumatic headaches, and tension headaches. Each component of this formulation plays a crucial role in managing these conditions.

Caffeine, a well-known stimulant, works by increasing alertness and reducing fatigue, thereby helping to alleviate the severity of headaches. Promethazine HCl, an antihistamine, aids in reducing inflammation and pain associated with headaches. Dihydroergotamine Mesylate, an ergot alkaloid, contributes to the reduction of headache frequency and severity by constricting blood vessels in the brain.

It is important to use this medication as directed by a healthcare provider. Overuse or misuse can lead to potential side effects and may not provide the desired relief. The recommended dose should not be exceeded, and this medication should not be used for more than 5 consecutive days. Potential side effects to be aware of include nausea, vomiting, dizziness, and drowsiness.

Understanding your medication is crucial for effective treatment. If you have any questions or concerns about this formulation, it is recommended to consult with your healthcare provider or pharmacist to ensure safe and effective use.

How Does it Work

A small arrow pointing down

This compounded formulation is a suppository that contains Caffeine 100 mg, Promethazine HCl 50 mg, and Dihydroergotamine Mesylate 5 mg. It is specifically designed to treat various types of headaches including migraines, cluster headaches, menstrual migraines, post-traumatic headaches, and tension headaches. The unique combination of these three active ingredients works synergistically to alleviate the symptoms associated with these conditions.

The caffeine component of this formulation functions to reduce the intensity of the headache. Promethazine HCl is included to help manage nausea and vomiting that often accompany severe headaches. Dihydroergotamine Mesylate is a potent medication that helps to decrease the frequency and severity of headaches.

To use this suppository, it should be inserted into the rectum as soon as possible after the onset of the headache. It is recommended to use this formulation no more than three times a day, and for no more than five consecutive days. If the headache persists beyond this period, it is advised to seek medical attention.

It is crucial to understand that this formulation should not be used in conjunction with other headache medications, as this could potentially increase the risk of side effects. Furthermore, this formulation is contraindicated in patients with a history of heart disease, high blood pressure, or stroke.

If you have any questions or concerns about this formulation or its usage, please do not hesitate to contact us. We are here to provide you with the necessary guidance and support.

Other Uses

A small arrow pointing down

This compounded formulation of Caffeine 100 mg/Promethazine HCl 50 mg/Dihydroergotamine Mesylate 5 mg Suppository is specifically designed for the treatment of various types of headaches including migraine, cluster headache, menstrual migraine, post-traumatic headache, and tension headache. It is crucial to understand that this formulation is not intended for any other use apart from the ones specified. It is also advised not to use this formulation in conjunction with other medications, as it could potentially heighten the risk of adverse effects.

Patients should be aware that this formulation may cause side effects such as drowsiness, dizziness, or blurred vision. Therefore, it is recommended not to operate heavy machinery or drive while under this medication. If any of these side effects are experienced, it is important to immediately contact a healthcare provider.

Furthermore, this formulation may interact with other medications. Therefore, patients should inform their healthcare provider about any other medications they are currently taking. This is to ensure the safe and effective use of this medication. If there are any questions or concerns regarding this formulation, patients are encouraged to seek advice from their healthcare provider.

Frequently Asked Questions

A small arrow pointing down

What is the purpose of this compounded formulation of Caffeine 100 mg/Promethazine HCl 50 mg/Dihydroergotamine Mesylate 5 mg Suppository?

This formulation is designed to deliver specific doses of caffeine, promethazine HCl, and dihydroergotamine mesylate. These medications can be used to treat a variety of conditions, including migraines, nausea, and vomiting, among others.

How is this suppository administered?

This suppository is typically inserted into a body cavity, most commonly the rectum or vagina. It then dissolves or melts, releasing the medication for local or systemic absorption.

What are the benefits of using a suppository?

Suppositories can provide a more direct route of administration, bypassing the digestive system which can be beneficial for those with gastrointestinal issues. They also allow for steady, controlled release of medication.

What are the potential side effects of this formulation?

Side effects can vary depending on the individual and the specific medications involved. Common side effects may include dizziness, drowsiness, or gastrointestinal discomfort. Always consult with your healthcare provider for a complete list of potential side effects.

Can this suppository be used in conjunction with other medications?

It's important to discuss all medications and supplements you're currently taking with your healthcare provider before starting any new treatment, including this suppository. Some substances may interact with the ingredients in this formulation.

How should this suppository be stored?

Suppositories should be stored in a cool, dry place, away from heat and direct sunlight. They should also be kept out of reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

Can anyone use this suppository?

This formulation is typically prescribed for specific conditions and may not be suitable for everyone. Always consult with your healthcare provider before starting any new medication.

What should I do if I experience an adverse reaction?

If you experience any adverse reactions, such as severe dizziness, difficulty breathing, or hives, seek immediate medical attention. For less severe reactions, contact your healthcare provider for guidance.

Can I stop using the suppository if my symptoms improve?

Even if your symptoms improve, do not stop using the suppository without first consulting your healthcare provider. Stopping medication prematurely may lead to a relapse or worsening of symptoms.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
NEW PRESCRIPTION ORDER FORM
1
Circle for steps.
Patient Information
2
Circle for steps.
Prescriber and Prescription Information
3
Circle for steps.
Fax order form to Bayview Pharmacy at 401-284-4506.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.