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This formulation is a rectal suppository containing Caffeine (75 mg), Indomethacin (25 mg), and Prochlorperazine (4 mg). It is a solid dosage form designed to be inserted into the rectum, where it dissolves or melts to release the medication. The medication is then absorbed locally or systemically.
The combination of these three active ingredients is used to treat a variety of disease states. Caffeine is a central nervous system stimulant that can help to increase alertness and reduce fatigue. Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce pain, inflammation, and fever. Prochlorperazine is an antiemetic and antipsychotic medication that can help to control severe nausea and vomiting, and treat psychotic disorders such as schizophrenia.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
This formulation combines three active ingredients: Caffeine, Indomethacin, and Prochlorperazine, in a rectal suppository dosage form. The suppository is a solid dosage form that is inserted into the rectum, where it dissolves or melts to release the medication. This allows for local or systemic absorption of the drugs.
Caffeine is a central nervous system stimulant that can help to increase alertness and reduce fatigue. It is often used in combination with other medications to enhance their effects. In this formulation, it may help to enhance the effects of the other two drugs, Indomethacin and Prochlorperazine.
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is used to treat moderate to severe pain, or inflammation caused by various conditions such as arthritis, gout, bursitis, or tendinitis.
Prochlorperazine is an anti-psychotic medicine that works by changing the actions of chemicals in your brain. It is used to treat psychotic disorders such as schizophrenia. It is also used to treat anxiety, and to control severe nausea and vomiting.
This combination of drugs in a rectal suppository form can be used to treat a variety of conditions, depending on the specific needs of the patient. The rectal route of administration allows for rapid absorption of the drugs, which can be beneficial in situations where oral administration is not possible or desirable. It also allows for local treatment of rectal conditions such as hemorrhoids or anal fissures.
As with any medication, it is important to use this formulation as directed by your healthcare provider. Side effects can occur, and may include stomach upset, headache, dizziness, or drowsiness. If any of these effects persist or worsen, or if you experience any other side effects, contact your healthcare provider immediately.
If you have any questions about this formulation, or if you would like more information, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.
This formulation combines caffeine, indomethacin, and prochlorperazine in a rectal suppository. Each of these active ingredients can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions. It's important for patients and prescribers to be aware of these potential interactions.
Caffeine is a central nervous system stimulant. It can interact with medications that also stimulate the nervous system, potentially leading to overstimulation and side effects like nervousness, insomnia, and rapid heartbeat. These include medications like pseudoephedrine, certain antidepressants, and some asthma medications. Caffeine can also interact with certain antibiotics and antifungal medications, potentially increasing the amount of caffeine in the bloodstream and intensifying its effects.
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation. It can interact with other NSAIDs, increasing the risk of gastrointestinal side effects like stomach ulcers and bleeding. Indomethacin can also interact with blood thinners, potentially increasing the risk of bleeding. Additionally, it can interact with certain blood pressure medications, potentially reducing their effectiveness.
Prochlorperazine is an antiemetic and antipsychotic medication. It can interact with other medications that depress the central nervous system, potentially leading to increased sedation and respiratory depression. These include opioids, benzodiazepines, and alcohol. Prochlorperazine can also interact with certain antihypertensive medications, potentially causing a drop in blood pressure. Additionally, it can interact with certain medications used to treat Parkinson's disease, potentially worsening symptoms.
This formulation is used to treat a variety of conditions. Caffeine is used to increase alertness and reduce fatigue. Indomethacin is used to reduce pain and inflammation associated with conditions like arthritis, gout, and bursitis. Prochlorperazine is used to control severe nausea and vomiting, and to treat schizophrenia and anxiety.
It's important for patients and prescribers to discuss all medications, supplements, and over-the-counter products being used before starting this formulation. This can help to identify potential interactions and develop a plan to manage them. If you have any questions about this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy.
The Caffeine 75 mg/Indomethacin 25 mg/Prochlorperazine 4 mg Rectal Suppository is a unique formulation designed to deliver medication directly into the bloodstream via the rectal route. This method of administration bypasses the digestive system, allowing for rapid absorption and onset of action. The suppository is a solid dosage form that is inserted into the rectum, where it dissolves or melts to release the medication.
Caffeine, a central nervous system stimulant, works by blocking adenosine receptors in the brain, thereby reducing fatigue and drowsiness. It also enhances the analgesic effect of other drugs, making it a useful component in this formulation.
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing the production of prostaglandins, substances in the body that cause inflammation, pain, and fever. By inhibiting their production, indomethacin helps to alleviate pain and reduce inflammation.
Prochlorperazine is an antiemetic and antipsychotic medication. It works by blocking dopamine receptors in the brain, which helps to control nausea and vomiting. It also has a calming effect, which can be beneficial in managing symptoms of certain mental health conditions.
This combination of medications can be used to treat a variety of conditions. The caffeine and indomethacin can work together to manage pain and inflammation, while the prochlorperazine can help control any associated nausea or vomiting. This makes the suppository particularly useful in conditions such as migraines, where all these symptoms may be present.
It's important to note that this formulation should be used under the guidance of a healthcare provider, as it contains potent medications that can have side effects. Always use the suppository as directed, and reach out to your healthcare provider or pharmacist if you have any questions or concerns.
If you have any questions about this formulation, or if you're a prescriber interested in using it for your patients, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.
A Caffeine 75 mg/Indomethacin 25 mg/Prochlorperazine 4 mg Rectal Suppository is a solid dosage form that is inserted into the rectum. It dissolves or melts to release medication for local or systemic absorption.
The primary components of this suppository are Caffeine (75 mg), Indomethacin (25 mg), and Prochlorperazine (4 mg).
This suppository is intended for rectal use. It should be inserted into the rectum as instructed by your healthcare provider.
The suppository is made to dissolve or melt once inserted into the body. If you believe it's not dissolving properly, contact your healthcare provider.
Recovery speed may vary depending on individual factors. However, the medications in the suppository are designed to be absorbed quickly for maximal effectiveness.
Not necessarily. Some individuals may experience side effects or have contraindications. It's crucial to discuss your medical history with your healthcare provider before using it.
Side effects can vary from person to person. Seek immediate medical attention if you experience severe or persistent side effects.
It's essential to consult with your healthcare provider to discuss if this suppository formulation is safe for you during pregnancy or breastfeeding.
You should discuss with your healthcare provider about all the medications, including over-the-counter drugs and dietary supplements, that you're currently taking before using this suppository.
Store this medication at room temperature. Avoid areas of extreme temperature or high humidity. Always keep medications out of reach from children and pets.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert 1 unwrapped suppository
