This formulation combines Cantharidin 1%, Podophyllum 5%, and Salicylic Acid 25% in a topical liquid preparation. It is specifically designed for direct application to the skin or mucosal surfaces, providing targeted therapeutic benefits. This formulation is often chosen for localized treatment or when avoiding systemic effects is desired.

Cantharidin is a vesicant, a substance that induces blistering, and is used in the treatment of warts and molluscum contagiosum. It works by causing the cells of the wart to shed or peel off. Podophyllum is a cytotoxic agent that has been used for the removal of genital warts. It works by preventing the growth of the cells that cause the warts. Salicylic Acid is a keratolytic (peeling agent) that causes shedding of the outer layer of skin. It is used to treat skin conditions such as acne, dandruff, psoriasis, and seborrheic dermatitis of the skin and scalp.

Together, these three active ingredients work synergistically to treat a variety of skin conditions. The Cantharidin causes the wart cells to shed, the Podophyllum inhibits the growth of new wart cells, and the Salicylic Acid helps to remove the outer layer of skin, aiding in the removal of the wart or other skin condition. This formulation is applied directly to the affected area, providing targeted treatment and minimizing systemic effects.

It is important to note that this formulation should only be applied to the affected area and should not be used on healthy skin. It should also not be used on the face, armpits, or genitals unless directed by a healthcare provider. Side effects may include skin irritation, redness, and peeling at the application site. If these side effects persist or worsen, contact your healthcare provider immediately.

As compounding pharmacists, we are here to answer any questions you may have about this formulation. Whether you are a patient or a prescriber, we are committed to providing you with the most accurate and up-to-date information. Please do not hesitate to reach out to us if you have any questions or concerns.

This formulation combines Cantharidin, Podophyllum, and Salicylic Acid, each with its own unique therapeutic properties. Cantharidin is a vesicant that causes blistering of the skin, often used in the treatment of warts. Podophyllum is a cytotoxic agent that inhibits cell growth and division, also used in the treatment of warts, particularly genital and anal warts. Salicylic Acid is a keratolytic agent that causes the outer layer of skin to shed, used in the treatment of various skin conditions including acne, dandruff, psoriasis, and seborrheic dermatitis.

It's important to note that while this formulation is designed for topical use, it can still interact with other medications. For instance, using other topical medications on the same area of skin can potentially increase absorption and risk of systemic side effects. Therefore, it's recommended to avoid using other topical treatments unless directed by a healthcare provider.

Additionally, certain systemic medications may interact with this formulation. For example, medications that increase skin sensitivity or dryness, such as retinoids, benzoyl peroxide, or certain antibiotics, may exacerbate the effects of Salicylic Acid. Similarly, medications that affect cell growth and division, such as certain chemotherapy drugs, may interact with Podophyllum.

It's also important to consider the potential for interactions with over-the-counter products and dietary supplements. For example, products containing alcohol can potentially increase skin dryness and irritation when used with Salicylic Acid. Similarly, certain supplements, such as those containing antioxidants or vitamin A, may interact with the effects of Cantharidin and Podophyllum.

Patients should be advised to inform their healthcare provider of all medications, over-the-counter products, and dietary supplements they are currently taking. Additionally, patients should be instructed to avoid applying this formulation to broken, irritated, or inflamed skin, as this can increase absorption and risk of systemic side effects.

Prescribers should consider the potential for drug interactions when prescribing this formulation, and monitor patients closely for signs of adverse effects. Additionally, prescribers should ensure that patients understand how to properly apply this formulation, and the importance of avoiding other topical treatments unless directed.

If you have any questions about this formulation or potential drug interactions, please don't hesitate to reach out to us. We are here to help ensure the safe and effective use of this medication.

The Cantharidin 1%/Podophyllum 5%/Salicylic Acid 25% Topical Liquid is a specially formulated treatment that combines the therapeutic properties of three active ingredients: Cantharidin, Podophyllum, and Salicylic Acid. This formulation is designed to be applied directly to the skin or mucosal surfaces, providing targeted treatment while minimizing systemic effects.

Cantharidin, a substance derived from the blister beetle, works by causing the skin to blister. This allows the removal of the affected skin cells, making it particularly effective in treating warts and molluscum contagiosum. It is a vesicant that causes acantholysis, a separation of the epidermal cells, leading to the formation of a blister beneath the wart. This blistering action helps to lift the wart off the skin for easy removal.

Podophyllum, on the other hand, is a plant-derived substance that has antiviral and antimitotic properties. It works by inhibiting cell division and growth, which is particularly useful in treating conditions like genital warts. Podophyllum resin interferes with the cell's ability to divide, effectively stopping the growth and spread of the wart cells.

Salicylic Acid is a keratolytic agent, which means it works by softening and dissolving the stratum corneum (the outermost layer of skin). This action helps to shed the skin cells from the wart or other skin lesions. Salicylic Acid also helps to break down the wart tissue, making it easier to remove, and it also has mild antiseptic properties.

Together, these three ingredients provide a comprehensive treatment for various skin conditions, including warts and molluscum contagiosum. The Cantharidin causes the wart to blister and lift from the skin, the Podophyllum inhibits the growth and spread of the wart cells, and the Salicylic Acid helps to break down and remove the wart tissue. This formulation is designed to provide targeted treatment, minimizing the risk of systemic side effects.

As with any medication, it's important to use this formulation as directed by a healthcare professional. Avoid contact with the eyes and mucous membranes, and do not apply to broken or inflamed skin. If you experience any adverse reactions, discontinue use and contact your healthcare provider immediately.

If you have any questions about this formulation or how to use it, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

In addition to its primary applications, the Cantharidin 1%/Podophyllum 5%/Salicylic Acid 25% topical liquid formulation has been found to be effective for several other uses. Some off-label uses include treatment of a variety of dermatological conditions outside of warts alone. Cantharidin, in particular, has been utilized for its blistering property to treat Molluscum contagiosum. Podophyllum is recognized for its potential effects in treating verrucae, condyloma, and other skin growths related to HPV. Of note, Salicylic Acid, as a well-known keratolytic agent, can also be utilized for wide-ranging conditions that involve abnormal accumulation of skin, such as psoriasis, calluses, and corns.

It's imperative for both patients and prescribers to be aware that this formulation should be used with caution. This liquid is meant for topical application only, and contact with the eyes or sensitive skin surfaces should be avoided. Furthermore, the compound can be highly toxic if ingested, and usage from a qualified healthcare provider is advised. It is highly recommended that pregnant women avoid this formulation due to the potential teratogenic effects of Podophyllum. Additionally, all three ingredients individually can cause local skin irritation, even more so when combined.

Lastly, while this formulation can bring substantial benefits in certain off-label indications, it's paramount to consult a medical professional before proceeding with any new treatment plans. Compounding pharmacists like our team at Bayview Pharmacy have unique knowledge and experience in this area, and are well-prepared to counsel both patients and prescribers on best practice administrations and safety measures. If you have any questions regarding this formulation, feel free to reach out to our team. We're always here to help inform and guide you to the most appropriate treatment solutions.