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Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules

FDA-approved generic
Dose form
Slow Release Capsules
Active ingredients
Carbidopa
Levodopa

Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules are a specially formulated medication designed to treat Parkinson's disease and Parkinson's-like symptoms such as shakiness, stiffness, and difficulty moving. The capsules are formulated with Methocel E4M, a controlled-release polymer, which allows for the gradual release of the active ingredients, Carbidopa and Levodopa, over an extended period of time.

This slow-release mechanism offers sustained therapeutic effects, reducing the frequency of dosing and improving patient compliance. The formulation is particularly beneficial for patients requiring a controlled and prolonged release profile for their medication.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Carbidopa
Levodopa
Slow Release Capsules
6538365a9f8bd0427b6224e6
Service area

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Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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The Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules are a specially formulated medication designed to manage the symptoms of Parkinson's disease and Parkinson's-like symptoms such as shakiness, stiffness, and difficulty moving. This formulation combines two active ingredients, Carbidopa and Levodopa, in a slow-release capsule format, providing a steady and prolonged release of the medication into the body.

Levodopa is converted into dopamine in the brain, helping to control movement and coordination. Carbidopa, on the other hand, prevents the breakdown of Levodopa in the bloodstream, allowing more Levodopa to reach the brain and thereby increasing its effectiveness. The combination of these two drugs helps to improve the symptoms of Parkinson's disease by increasing the amount of dopamine in the brain.

The unique feature of this formulation is the use of Methocel E4M, a type of controlled-release polymer. This polymer is designed to gradually release the encapsulated medication over an extended period of time. This slow-release mechanism offers sustained therapeutic effects, reducing the frequency of dosing and improving patient compliance, particularly beneficial for patients who have difficulty maintaining a regular medication schedule.

It's important to note that while this medication helps manage symptoms of Parkinson's, it does not cure the disease. Side effects may include nausea, vomiting, loss of appetite, and trouble sleeping. It's crucial to discuss these potential side effects with your healthcare provider to ensure this medication is the right choice for you.

As compounding pharmacists, we are committed to providing the highest quality medications tailored to individual patient needs. If you have any questions about the Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules or any other medication, please don't hesitate to reach out to us at Bayview Pharmacy. We are here to help.

Drug Interactions

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Carbidopa/Levodopa slow-release capsules are primarily used in the management of Parkinson's disease symptoms. This combination medication works by increasing the levels of certain chemicals in the brain that help with symptoms such as tremors, stiffness, and difficulty moving. Carbidopa helps to enhance the effects of Levodopa and reduce some of its side effects such as nausea and vomiting.

It's important to be aware of potential drug interactions that can affect the effectiveness of Carbidopa/Levodopa and increase the risk of side effects. Certain medications can interact with Carbidopa/Levodopa, including antipsychotic drugs (such as chlorpromazine, haloperidol), certain drugs used to treat high blood pressure (such as methyldopa, reserpine), and other drugs used to treat Parkinson's disease (such as selegiline, amantadine).

Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: certain antidepressants (including tricyclics such as amitriptyline, SSRIs such as fluoxetine), certain medications used to treat high blood pressure or irregular heartbeat (such as beta blockers like metoprolol, calcium channel blockers like verapamil), and certain antifungal medications (such as itraconazole, ketoconazole).

Carbidopa/Levodopa can also interact with certain dietary substances. For example, high-protein diets can decrease the absorption of Levodopa, which may reduce the effectiveness of this medication. It's recommended to have a balanced diet while taking this medication. Also, avoid taking supplements that contain iron, as iron can reduce the absorption of this medication.

It's also important to note that Carbidopa/Levodopa can cause a false result in certain lab tests for urine ketones. Make sure laboratory personnel and all your doctors know you use this drug.

Remember that your healthcare provider has prescribed this medication because they have judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. However, if you notice any side effects, contact your healthcare provider promptly.

If you have any questions about Carbidopa/Levodopa slow-release capsules, or about potential drug interactions, please don't hesitate to reach out to us at Bayview Pharmacy.

How Does it Work

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The Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules work by combining two active ingredients, Carbidopa and Levodopa, in a controlled-release formulation. This formulation is designed to gradually release the medication over an extended period of time, providing sustained therapeutic effects and reducing the frequency of dosing. This is achieved through the use of Methocel E4M, a type of controlled-release polymer.

Levodopa is a medication that is converted into dopamine in the brain. Dopamine is a neurotransmitter that is essential for normal brain function, including the control of movement. In conditions such as Parkinson's disease, the amount of dopamine in the brain is reduced, leading to symptoms such as tremors, stiffness, and difficulty with movement. By providing a source of Levodopa, this medication helps to increase the levels of dopamine in the brain, thereby reducing these symptoms.

Carbidopa is included in this formulation to enhance the effectiveness of Levodopa. On its own, a large portion of Levodopa is broken down in the body before it can reach the brain. Carbidopa works by inhibiting this breakdown, allowing more Levodopa to reach the brain and be converted into dopamine. This means that lower doses of Levodopa can be used, reducing the risk of side effects.

The use of Methocel E4M in this formulation allows for a slow and controlled release of the active ingredients. This means that the medication is released gradually over time, providing a steady level of medication in the body. This can help to reduce fluctuations in symptoms and provide more consistent relief. It also means that the medication needs to be taken less frequently, which can improve patient compliance.

This formulation is used to treat conditions where there is a deficiency of dopamine in the brain, such as Parkinson's disease and certain forms of parkinsonism. It can help to reduce symptoms such as tremors, stiffness, and difficulty with movement, improving the quality of life for patients with these conditions.

If you have any questions about this formulation, or if you would like more information, please do not hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your medication.

Frequently Asked Questions

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What is Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules?

Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules are a type of medication that uses a controlled-release polymer called Methocel E4M to gradually release the encapsulated medication over an extended period of time. This provides sustained therapeutic effects, requires less frequent dosing, and improves patient compliance.

Why are Carbidopa/Levodopa capsules formulated with Methocel E4M?

Methocel E4M is used to create a controlled-release profile for the medication. This means that the active ingredients are released slowly over an extended period of time. This approach provides sustained therapeutic effects and reduces the need for frequent dosing, which can improve patient compliance.

What does “slow release” mean?

Slow release refers to the controlled and gradual release of the active ingredients over an extended period of time. This helps to maintain a steady level of the medication in the body, and can allow for less frequent dosing.

What are the benefits of using a slow release formulation?

Slow release formulations can offer several benefits. This includes sustained therapeutic effects, less frequent dosing, and improved patient compliance, especially for medications that require a controlled and prolonged release profile.

What is a controlled-release polymer?

A controlled-release polymer is a substance that can gradually release a drug or active ingredient over a specified period of time. Methocel E4M, used in this formulation, is an example of such a polymer.

How often do I need to take the Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules?

Because it is a slow release medication, the dosing frequency will typically be less than with traditional medications. However, the exact dosing schedule should be guided by your doctor's instructions.

Will this slow release formulation interact with other medications?

Like all medications, Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules could potentially interact with other medications. Discuss all medications, supplements, and over-the-counter products you are taking with your health care provider to ensure safety.

Can anyone use this slow release formulation?

While the slow release formulation has many benefits, it is not suitable for everyone. Patients with certain health conditions or who are on certain medications may not be able to use it. As with all medications, it should only be used under the supervision of a healthcare provider.

Does the slow release formulation improve treatment effectiveness?

However, individual patient responses can vary.

Can I open or chew the Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules?

No, opening or chewing the capsules can disrupt the controlled release profile of the medication, impacting its effectiveness. The capsules should be swallowed whole. If you have difficulty swallowing pills, consult with your healthcare provider for guidance.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Carbidopa 25 mg/Levodopa 100 mg Slow Release (MEM4) Oral Capsules
Slow Release Capsules
controlled

Take 1 capsule by mouth

Twice daily