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Formulas

Clarithromycin 250 mg Rectal Suppository

FDA-approved generic
Dose form
Suppository
Active ingredients
Clarithromycin

The Clarithromycin 250 mg Rectal Suppository is a solid dosage form designed for insertion into the rectum. Upon insertion, the suppository dissolves or melts, releasing the antibiotic Clarithromycin for local or systemic absorption. This formulation is primarily used to treat bacterial infections, including respiratory tract infections, skin infections, and Helicobacter pylori infection. It is also used in combination with other medications to eliminate certain types of bacteria that cause stomach ulcers.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clarithromycin
Suppository
653f9b1b589c1982890bc849
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Clarithromycin 250 mg Rectal Suppository is a solid dosage form designed for insertion into the rectum. This formulation is specifically designed to dissolve or melt once inserted, releasing the medication for local or systemic absorption. The primary active ingredient in this formulation is Clarithromycin, a macrolide antibiotic that is used to treat a variety of bacterial infections.

Clarithromycin works by inhibiting the growth of bacteria, thereby helping to eliminate the infection. This makes it a versatile treatment option for a variety of bacterial infections.

As a rectal suppository, this formulation offers several advantages. It can be particularly useful for patients who have difficulty swallowing pills or for those who are unable to take medication orally due to nausea or vomiting. Additionally, rectal administration can provide a more rapid onset of action compared to oral administration, as the medication is absorbed directly into the bloodstream, bypassing the digestive system.

As with all antibiotics, it's crucial to take the full course of treatment as prescribed, even if symptoms improve before the medication is finished. This helps to prevent the bacteria from becoming resistant to the antibiotic.

As compounding pharmacists, we are able to customize this formulation to meet the specific needs of individual patients. This can include adjusting the dosage, changing the delivery method, or adding flavorings to make the medication more palatable. We are also available to answer any questions or concerns you may have about this medication. Please don't hesitate to reach out to us if you need any additional information.

Drug Interactions

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Clarithromycin is a macrolide antibiotic that works by stopping the growth of bacteria. It is used to treat a wide variety of bacterial infections. This antibiotic treats only bacterial infections and will not work for viral infections. Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. As a rectal suppository, the medication is typically used for local treatment, but can also be absorbed systemically.

It's important to be aware of potential drug interactions with Clarithromycin. Certain medications should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.

Clarithromycin can interact with drugs such as warfarin, leading to an increased risk of bleeding. It can also interact with statins (cholesterol-lowering drugs) like simvastatin, atorvastatin, and lovastatin, increasing the risk of muscle breakdown (rhabdomyolysis). Other drugs that can interact with clarithromycin include colchicine, sildenafil, tadalafil, vardenafil, theophylline, carbamazepine, and certain HIV medications. Always inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and dietary supplements.

Clarithromycin can also interact with certain foods. For example, grapefruit juice can increase the amount of this medication in your bloodstream. Consult your healthcare provider about the use of grapefruit products with this medication.

It's also important to note that Clarithromycin can cause a prolonged QT interval, which is a heart rhythm disorder that can cause serious irregular heartbeats, fainting, or sudden death. If you are taking medication to treat heart rhythm disorder or have a history of long QT syndrome, inform your healthcare provider.

Remember, this is not a complete list of possible drug interactions. Keep a list of all the products you use and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. If you have any questions or concerns about drug interactions or the use of Clarithromycin 250 mg Rectal Suppository, please reach out to us at Bayview Pharmacy. We are here to help.

How Does it Work

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Clarithromycin 250 mg Rectal Suppository is a solid dosage form that is inserted into the rectum where it dissolves or melts to release the medication. The active ingredient, Clarithromycin, is a type of antibiotic known as a macrolide. It works by inhibiting the growth of bacteria by blocking their protein synthesis. This is achieved by binding to the 50S ribosomal subunit of the bacteria, which prevents the translocation of peptides. This action stops the bacteria from growing, which allows the body's immune system to kill them.

Once the suppository is inserted into the rectum, it begins to dissolve due to the body's natural heat. As it dissolves, the Clarithromycin is released and absorbed into the bloodstream through the rectal tissue. This route of administration can be particularly beneficial for patients who have difficulty swallowing tablets or for those who experience gastrointestinal side effects with oral administration. The rectal route can also provide a faster onset of action compared to oral administration, as the medication does not need to pass through the digestive system.

Clarithromycin is used to treat a variety of bacterial infections. This includes respiratory tract infections such as pneumonia and bronchitis, skin infections, and Helicobacter pylori infections, which can cause stomach ulcers. It is also used in combination with other medications to treat Mycobacterium avium complex (MAC) infections in people with HIV.

As with any medication, there may be side effects associated with the use of Clarithromycin rectal suppositories. These can include local irritation or discomfort at the site of administration. Systemic side effects can include nausea, vomiting, stomach pain, and diarrhea. If these side effects persist or worsen, or if you experience any serious side effects such as hearing loss or signs of liver disease, it's important to seek medical attention immediately.

It's also important to inform your healthcare provider of all the medications you are currently taking, as Clarithromycin can interact with other drugs. This includes prescription and over-the-counter medications, as well as vitamins and herbal supplements. If you have any questions about Clarithromycin 250 mg Rectal Suppositories, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Frequently Asked Questions

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What is Clarithromycin 250 mg Rectal Suppository?

Clarithromycin 250 mg Rectal Suppository is a solid dosage form of the antibiotic Clarithromycin, which is administered via the rectum. It works by dissolving or melting after insertion to release the medication for local or systemic absorption to fight bacterial infections.

How does a rectal suppository work?

Once inserted into the rectum, the suppository begins to dissolve or melt at body temperature. It releases the medication it contains into the surrounding area, where it gets absorbed into the bloodstream for local or systemic action.

What is Clarithromycin used for?

Clarithromycin is an antibiotic used to combat various bacterial infections. Its effectiveness covers a range of disorders like respiratory tract infections, skin infections and certain sexually transmitted infections.

Why is Clarithromycin delivered as a rectal suppository?

This can help with patients who have difficulty in swallowing oral medications, or to avoid possible side effects connected to the drug’s passage through the digestive system.

Is Clarithromycin 250 mg Rectal Suppository safe for everyone?

No, not everyone should use this medication. Individuals with certain conditions like liver or kidney disease, heart rhythm disorders, or a history of Long QT syndrome may not be able to use this medication. Always consult with a healthcare provider before starting a new medication.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Are there any side effects to expect from using Clarithromycin 250 mg Rectal Suppository?

Similar to other medications, this can produce side effects such as diarrhoea, nausea, vomiting, stomach pain and headache. If these persist or worsen, promptly inform your healthcare provider.

How should I store Clarithromycin 250 mg Rectal Suppository?

Store this medication in a cool, dry place away from light and moisture. Always keep medications out of reach of children and pets. Do not store it in the bathroom or near a sink.

What should I do in the case of a Clarithromycin overdose?

If you suspect an overdose, seek medical help immediately. Symptoms may include severe nausea, vomiting, abdominal discomfort, or diarrhoea. In such cases, do not induce vomiting unless directed to do so by a healthcare provider.

Should Clarithromycin 250 mg Rectal Suppository be taken with or without food?

Since this is a rectal suppository, food intake doesn't impact its efficacy. However, it's generally recommended to maintain a regular eating schedule when taking antibiotics.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clarithromycin 250 mg Rectal Suppository
Suppository
30 suppositories
controlled

Insert 1 unwrapped suppository

Twice daily