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Clindamycin 150 mg Vaginal Suppository

The Clindamycin 150 mg Vaginal Suppository is a solid dosage form specifically designed for insertion into the vagina. Upon insertion, it dissolves or melts, releasing the antibiotic Clindamycin locally. This formulation is primarily used to treat bacterial infections of the vagina, such as bacterial vaginosis, by inhibiting the growth of bacteria. It may also be used for other conditions as determined by a healthcare provider.

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Formula Information

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Clindamycin 150 mg Vaginal Suppository is a solid dosage form that is designed to be inserted into the vagina. Once inserted, the suppository dissolves or melts, releasing the medication for local or systemic absorption. This formulation is specifically designed to deliver the antibiotic clindamycin directly to the site of infection, providing targeted treatment and minimizing systemic side effects.

Clindamycin is an antibiotic that works by stopping the growth of bacteria. It is used to treat a wide variety of bacterial infections, including those that occur in the female reproductive system. In the form of a vaginal suppository, clindamycin can effectively treat bacterial vaginosis, a common condition caused by an imbalance of bacteria in the vagina. This condition can cause symptoms such as itching, burning, and unusual discharge. By delivering clindamycin directly to the site of infection, the suppository can quickly reduce these symptoms and eliminate the infection.

For patients using this formulation, it is important to use it exactly as directed by your healthcare provider. The suppository should be inserted into the vagina, typically at bedtime, to allow the medication to be absorbed while you sleep. It is also important to continue using the medication for the full course of treatment, even if symptoms improve before the medication is finished. Stopping the medication too early may allow the bacteria to continue to grow, which may result in a return of the infection.

For prescribers, it is important to note that clindamycin vaginal suppositories are generally well-tolerated, but they can cause side effects in some patients. These may include vaginal itching or burning, stomach cramps, or diarrhea. If these side effects are severe or do not go away, the patient should be advised to contact their healthcare provider. Additionally, patients should be advised not to have sexual intercourse while using this medication, as it can cause irritation and may also interfere with the effectiveness of the medication.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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Clindamycin is an antibiotic that fights bacteria in the body. It is used to treat serious infections caused by bacteria. However, it is important to be aware of potential drug interactions when using this medication. Drug interactions can change how your medications work or increase your risk for serious side effects.

Clindamycin may interact with certain live bacterial vaccines (such as typhoid vaccine). Using such vaccines while you are using this medication may cause the vaccines not to work as well. Therefore, it is recommended to avoid using live bacterial vaccines during treatment with clindamycin.

Clindamycin can also interact with erythromycin. Both are antibiotics, but they can counteract each other's effects when used together. Therefore, they should not be used concurrently. If you are currently taking erythromycin, make sure to inform your healthcare provider.

Furthermore, clindamycin may interact with neuromuscular blockers. When used together, they can cause increased muscle weakness and breathing difficulties. If you are using any neuromuscular blockers, inform your healthcare provider before starting clindamycin.

It's important to note that this does not include all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Clindamycin works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for virus infections (such as common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Clindamycin is used to treat a wide variety of bacterial infections. It is an antibiotic that works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for virus infections (such as common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

If you have any questions about the potential interactions or how to use this medication, do not hesitate to reach out to us. We are here to help and provide you with the most accurate and up-to-date information.

How Does it Work

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Clindamycin 150 mg Vaginal Suppository is a solid dosage form that is inserted into the vagina, where it dissolves or melts to release the medication. The active ingredient, Clindamycin, is an antibiotic that works by stopping the growth of bacteria. This antibiotic treats only bacterial infections and will not work for viral infections. It is used to treat a wide variety of bacterial infections, including those that cause acne. It is also used to treat bacterial vaginosis, an infection caused by an overgrowth of certain kinds of bacteria in the vagina.

Once the suppository is inserted into the vagina, it begins to dissolve or melt due to the body's natural heat. As it dissolves, the Clindamycin is released and absorbed by the vaginal tissues. The medication then works locally to kill the bacteria causing the infection, reducing symptoms such as discharge, odor, and discomfort. In some cases, Clindamycin can also be absorbed into the bloodstream and work systemically to fight bacterial infections elsewhere in the body.

It's important to note that Clindamycin should not be used by patients who are allergic to it or to lincomycin, a similar antibiotic. It should also be used with caution in patients with a history of gastrointestinal disease, particularly colitis, since Clindamycin has been associated with severe colitis. As with all antibiotics, it's crucial to take the full course of medication, even if symptoms improve before the medication is finished. Stopping the medication too early may allow the bacteria to continue to grow, which may result in a return of the infection.

For prescribers, it's important to note that the dose and duration of treatment with Clindamycin may vary based on the type and severity of the infection. The typical dose for treating bacterial vaginosis is one Clindamycin 150 mg Vaginal Suppository inserted into the vagina once daily at bedtime for seven days. However, the dose may be adjusted based on the patient's response to treatment and the severity of the infection.

If you have any questions about Clindamycin 150 mg Vaginal Suppository, its uses, or its potential side effects, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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Clindamycin is an antibiotic that fights bacteria in the body. Although Clindamycin 150 mg Vaginal Suppositories are typically used for treating bacterial vaginosis (an infection of the vagina), they may also be applied in other contexts for their antimicrobial properties. For instance, they could be used to manage other types of vaginal infections caused by susceptible bacteria. Research also suggests their potential use in preventing preterm birth in women with bacterial vaginosis, given clindamycin's ability to control harmful bacteria growth.

Other off-label uses may include treatment of pelvic inflammatory disease in conjunction with other antibiotics, prevention of streptococcal infections in patients who are allergic to penicillin, or prevention of endocarditis (an infection of the heart's inner lining) before dental procedures in high-risk individuals. Note that such uses should only be considered in consultation with a healthcare professional, as they involve careful evaluation of possible benefits against the associated risks.

Another conceivable use is in treating acne, as clindamycin can reduce the amount of acne-causing bacteria and has anti-inflammatory effects to help soothe inflamed skin. Although topical application is typical for acne, a different dose form, such as a suppository, could potentially benefit individuals with hard-to-reach areas of acne or sensitive skin that cannot tolerate topical application. Again, patient-specific factors and potential risks should be discussed and evaluated with a healthcare provider.

Prescribers who consider utilizing these Clindamycin 150 mg Vaginal Suppositories for any of these other applications should remember that the dose form is designed for local release of medication into the vaginal cavity, which may limit systemic absorption and present challenges for conditions requiring systemic treatment. Furthermore, the use of antibiotics should always take into consideration the risk of antibiotic resistance and potential side-effects, such as irritation or allergic reactions.

If you have any more questions regarding this formulation or its potential uses, don't hesitate to reach out to us at Bayview Pharmacy. As a team of experienced compounding pharmacists, we are always here to assist you and work together with you and your healthcare provider to find the most suitable solutions for your health needs.

Frequently Asked Questions

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What is a Clindamycin 150 mg Vaginal Suppository?

This is a solid dosage form of medicine that is designed to be inserted into the vagina. Once inserted, it dissolves or melts to release the Clindamycin medication for local or systemic absorption by the body.

How does the Clindamycin Vaginal Suppository work?

The suppository is designed to be gradually absorbed by the body after it dissolves or melts in the vagina, delivering the Clindamycin medication to the affected area directly.

What is Clindamycin used for?

Clindamycin is an antibiotic that fights bacteria in the body. It is primarily used to treat serious infections caused by bacteria, including vaginal infections.

Can I use this suppository rectally?

No, this particular suppository is designed for vaginal use only. Using it rectally could cause uncomfortable side effects and may not deliver the medication as effectively.

How often should I use the Clindamycin Vaginal Suppository?

Use the Clindamycin vaginal suppository exactly as your healthcare provider has directed. The frequency of use will depend on your specific medical condition and your individual treatment plan.

What side effects can occur with this medication?

While most users do not experience severe side effects, potential side effects can include vaginal irritation or burning, stomach pain, or diarrhoea. If you experience a serious allergic reaction or any unexpected side effects, contact your healthcare provider immediately.

How should I store Clindamycin Vaginal Suppositories?

It’s important to store this medication at room temperature, away from light and moisture. Do not store in the bathroom or freeze it. Keep out of reach of children.

Can I use this drug if I am pregnant or breastfeeding?

Before using Clindamycin Vaginal Suppository, talk to your healthcare provider about potential risks and benefits if you are pregnant or breastfeeding.

What happens if I miss a dose of Clindamycin Vaginal Suppository?

If you miss a dose of this medication, use it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and continue with your regular dosage schedule. Do not double up.

What should I do in case of an overdose?

If you suspect an overdose or if the suppository is swallowed, contact a healthcare professional or poison control center immediately. Symptoms of overdose may include severe dizziness, nausea, or vomiting.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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