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Clindamycin 2%/Hydrocortisone1%/Salicylic Acid 3% Topical Lotion

This formulation is a combination of Clindamycin 2%, Hydrocortisone 1%, and Salicylic Acid 3% in a topical lotion form. It is a liquid or semi-liquid preparation intended for external application to the skin. The lotion provides a smooth and spreadable consistency, offering moisturizing, soothing, or therapeutic effects for specific skin conditions. It promotes the absorption of the active ingredients for localized treatment.

Clindamycin is an antibiotic that prevents bacteria from growing on the skin. Hydrocortisone is a corticosteroid that reduces redness, itching, and swelling. Salicylic Acid helps to shed dead skin cells from the top layer and decrease redness and swelling (inflammation). This decreases the number of pimples that form and speeds healing.

This formulation is used to treat various skin conditions such as acne, dermatitis, psoriasis, and eczema. It can also be used to treat other conditions as determined by a healthcare professional.

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Topical Lotion
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Formula Information

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This formulation combines Clindamycin, Hydrocortisone, and Salicylic Acid in a topical lotion designed for external application to the skin. Clindamycin is an antibiotic that prevents bacteria from growing on the skin. It is used to treat severe acne, a condition characterized by the presence of pimples, blackheads, and whiteheads. By reducing the number of bacteria, Clindamycin helps to decrease the number of acne lesions.

Hydrocortisone is a corticosteroid that works by reducing the swelling, redness, and itching that occurs in the skin conditions. It is used to treat a variety of skin conditions such as allergic reactions, eczema, and psoriasis. Hydrocortisone provides relief from itching and inflammation by suppressing the immune response and decreasing inflammation in the skin.

Salicylic Acid is a keratolytic (peeling agent) that causes shedding of the outer layer of skin. It is used to treat conditions such as dandruff, seborrheic dermatitis of the scalp, calluses, corns, common warts, and plantar warts, psoriasis, and acne. Salicylic Acid helps to soften and remove the outer layer of the skin, promoting the shedding of skin cells and reducing the buildup of scales and dead skin cells.

The lotion base provides a smooth and spreadable consistency, offering moisturizing, soothing, or therapeutic effects for specific skin conditions. It promotes the absorption of these active ingredients for localized treatment, enhancing their effectiveness. This formulation is designed to provide relief from various skin conditions, improving the skin's appearance and texture.

Patients should apply this lotion to the affected area as directed by their healthcare provider. It is important to use this medication regularly to get the most benefit from it. Patients should not use more of this product, use it more often, or keep using it longer than prescribed by their doctor. Side effects may include skin irritation, dryness, peeling, or redness. If these effects persist or worsen, patients should inform their doctor or pharmacist promptly.

Prescribers should consider the patient's skin condition, the severity of the condition, and the patient's response to treatment when deciding on the appropriate dose and frequency of this formulation. It is important to monitor the patient's progress and adjust the treatment as necessary.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This formulation of Clindamycin 2%/Hydrocortisone1%/Salicylic Acid 3% Topical Lotion is designed to treat a variety of skin conditions. Clindamycin is an antibiotic that works by stopping the growth of bacteria, and is used to treat acne. Hydrocortisone is a corticosteroid that reduces redness, itching, and swelling, and is used to treat a variety of skin conditions such as eczema, dermatitis, allergies, and rash. Salicylic Acid is a keratolytic (peeling agent) that causes shedding of the outer layer of skin, and is used to treat conditions such as psoriasis, dandruff, acne, corns, and warts.

It's important to be aware of potential drug interactions when using this formulation. Clindamycin, when used topically, is generally not expected to interact with other medications. However, it may interact with neuromuscular blocking agents, so caution should be exercised if you are taking these types of medications. Hydrocortisone, when used topically, is also generally not expected to interact with other medications. However, it may interact with drugs such as aldesleukin, mifepristone, and drugs that can cause skin thinning (for example, isotretinoin). Salicylic Acid, when used topically, is generally not expected to interact with other medications. However, it may interact with other skin products that can cause irritation and dryness (for example, abrasive soaps and cleansers, skin peeling agents, and alcohol-containing products).

It's also important to note that using this formulation with other topical medications may increase the risk of skin irritation. Therefore, it's recommended to use other topical medications at different times of the day to reduce this risk. Also, avoid using this formulation on broken or infected skin, or on large areas of skin, unless directed by your doctor. This can increase the risk of absorption into the bloodstream and the potential for side effects.

As with any medication, it's important to use this formulation as directed by your healthcare provider. If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. We're here to help ensure that your treatment is safe and effective.

How Does it Work

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This formulation combines the antibiotic properties of Clindamycin, the anti-inflammatory and immunosuppressive effects of Hydrocortisone, and the keratolytic and comedolytic actions of Salicylic Acid to treat a variety of skin conditions. The lotion form allows for easy application and absorption of these active ingredients into the skin for localized treatment.

Clindamycin, an antibiotic, works by inhibiting bacterial protein synthesis, specifically in the 50S subunit of the bacterial ribosome, thereby stopping the growth of bacteria. It is particularly effective against Propionibacterium acnes, a bacterium linked to the development of acne. By reducing the population of these bacteria on the skin, Clindamycin helps to reduce the number of acne lesions.

Hydrocortisone, a corticosteroid, works by decreasing the body's immune response to reduce inflammation, redness, and swelling. It does this by mimicking the effects of hormones your body naturally produces in your adrenal glands. When applied to the skin, Hydrocortisone acts on the cells to prevent the release of certain chemicals that cause inflammation. This can help to reduce symptoms such as pain, redness, and swelling, making it useful in treating conditions such as eczema and dermatitis.

Salicylic Acid, a beta hydroxy acid (BHA), works by softening and dissolving the keratin plug in the follicle and by promoting the shedding of dead skin cells. This helps to unclog pores and reduce the formation of comedones, which are often the precursor to pimples. Salicylic Acid also has mild anti-inflammatory properties which can help to calm inflamed acne.

Together, these three active ingredients work synergistically to treat a variety of skin conditions. The Clindamycin reduces the bacterial population, the Hydrocortisone reduces inflammation and redness, and the Salicylic Acid helps to unclog pores and reduce the formation of comedones. The lotion base provides a smooth and spreadable consistency, allowing for easy application and promoting the absorption of these active ingredients into the skin for localized treatment.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This medication is primarily created for the localized treatment of certain skin conditions. Its formulation contains clindamycin, an antibiotic that halts bacterial growth, salicylic acid to shed dead skin cells and reduce redness and swelling, and hydrocortisone to relieve skin discomfort. The combination of these three active ingredients is intended to treat skin conditions like acne and dermatitis effectively.

Apart from its primary use, this Clindamycin 2%/Hydrocortisone1%/Salicylic Acid 3% Topical Lotion can be used to manage other skin disorders. Conditions like rosacea, and eczema, which are characterized by skin inflammation and irritation, may benefit from this formulation due to its anti-inflammatory and soothing effects.

This particular formula can also be useful for individuals who have keratosis pilaris, a condition associated with small, rough red bumps as hydrocortisone can help to reduce the inflammation and salicylic acid aids in the removal of dead skin cell build-up. Furthermore, for patients suffering from seborrheic dermatitis, a condition that often results in flaky, dandruff-like scales on the skin, this lotion can be beneficial due to its combination of anti-inflammatory and keratolytic, or skin-shedding, properties.

Individuals who have folliculitis, an inflammation of hair follicles, may also find relief using this lotion due to the antibacterial and anti-inflammatory ingredients. Lastly, this lotion's active constituents make it suitable for the management of insect bites and stings as hydrocortisone can reduce swelling, itchiness, and discomfort caused by these types of minor skin irritations.

Before employing this medication for off-label use, please ensure to consult your healthcare provider. They can best determine if this formulation is suitable for your specific skin condition and guide you on the correct dosage and application frequency. As always, if you have any questions, please reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is the Clindamycin 2%/Hydrocortisone1%/Salicylic Acid 3% Topical Lotion?

This is a liquid or semi-liquid formulation designed for external application on the skin. It comprises clindamycin, hydrocortisone, and salicylic acid in percentages of 2%, 1%, and 3% respectively. These active ingredients are absorbed through the skin to address specific skin ailments.

What is the specific purpose of this topical lotion?

This topical lotion offers moisturizing, soothing, or therapeutic effects for specific skin conditions. It is meant for localized treatment, providing relief directly to the affected area(s).

What is the nature of this lotion consistency?

This lotion typically has a smooth and spreadable consistency, allowing for easy application and optimal coverage on your skin.

What are the benefits of having the active ingredients in this lotion?

Each active ingredient plays an essential role in treatment. Clindamycin is an antibiotic that fights bacteria, Hydrocortisone is a corticosteroid that reduces swelling, itching, and redness, and Salicylic Acid helps to shed dead skin cells from the outer layer of your skin.

Is this lotion suitable for all skin types?

Generally, the lotion is suitable for different skin types but individual reactions may vary. It is always advisable to test the lotion on a small patch of skin and wait for 24 hours to see if any adverse reaction happens.

How often should I apply this topical lotion?

It is essential to follow your healthcare provider’s instructions on using this medication. The frequency of application will depend on the severity and type of your skin condition.

Should I apply this lotion on broken or sensitive skin?

No, it is recommended not to apply this lotion on broken, sensitive or irritated skin unless directed by your healthcare provider.

Can this lotion be used along with other skincare or topical products?

Before using this lotion in conjunction with other skincare products, it is crucial to consult with your healthcare provider as some products may influence the absorption rate of the active ingredients or cause skin irritations.

How should I store this lotion?

This lotion should be stored at room temperature, away from heat and direct sunlight. It should also be kept out of reach of children and pets.

What should I do if I experience any adverse effects?

If you experience any adverse effects such as severe skin irritation or allergic reactions, you should discontinue usage and consult a healthcare provider immediately.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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