The Clindamycin 50 mg/Hydrocortisone Acetate 90 mg Vaginal Suppository is a solid dosage form designed for insertion into the vagina. Once inserted, the suppository dissolves or melts, releasing the medication for local or systemic absorption. This formulation combines the antibiotic properties of Clindamycin and the anti-inflammatory and immunosuppressive effects of Hydrocortisone Acetate to treat a variety of disease states.

Clindamycin is a lincosamide antibiotic that works by inhibiting bacterial protein synthesis, effectively stopping the growth of bacteria. It is commonly used to treat serious infections caused by bacteria, including infections of the respiratory tract, skin, pelvis, vagina, and abdomen. In this formulation, Clindamycin is used to treat bacterial vaginosis, a common vaginal infection in women.

Hydrocortisone Acetate, on the other hand, is a corticosteroid that works by reducing inflammation, itching, and redness. It is commonly used to treat a variety of skin conditions such as eczema, dermatitis, allergies, and rash. In this formulation, Hydrocortisone Acetate is used to reduce the inflammation and discomfort associated with bacterial vaginosis.

The combination of Clindamycin and Hydrocortisone Acetate in a vaginal suppository form allows for targeted treatment of the infection and associated symptoms. The suppository is inserted directly into the vagina, allowing the medication to be delivered directly to the site of infection. This not only increases the effectiveness of the treatment but also reduces the risk of systemic side effects.

It is important for patients to use this medication exactly as prescribed by their healthcare provider. The suppository should be inserted into the vagina usually once a day at bedtime. It is not recommended to use this medication if you have a history of hypersensitivity to Clindamycin, lincomycin, or any component of the formulation. Common side effects may include vaginal itching or discharge, nausea, vomiting, stomach pain, or diarrhea. If these side effects persist or worsen, contact your healthcare provider immediately.

For prescribers, it is crucial to consider the patient's overall health status, other medications, and potential drug interactions before prescribing this formulation. It is also important to educate patients on the proper use of the suppository and the importance of completing the full course of treatment, even if symptoms improve before the medication is finished.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

The combination of Clindamycin and Hydrocortisone Acetate in a vaginal suppository form is used to treat bacterial infections and inflammation in the vaginal area. Clindamycin is an antibiotic that works by stopping the growth of bacteria, while Hydrocortisone Acetate is a corticosteroid that reduces swelling, itching, and redness.

It's important to be aware of potential drug interactions when using this formulation. Clindamycin can interact with certain drugs such as erythromycin and neuromuscular blockers. Using Clindamycin with erythromycin, another antibiotic, can decrease the effectiveness of either drug. Neuromuscular blockers, used during surgical procedures, can interact with Clindamycin, potentially enhancing their effects and leading to increased muscle weakness.

Hydrocortisone Acetate can also interact with certain medications. For instance, it can decrease the effectiveness of vaccines and other immunizations, as it suppresses the immune system. It can also interact with drugs like insulin, warfarin, and certain antifungal medications, altering their effects. Therefore, it's crucial to inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and herbal supplements.

While this formulation is generally safe for most patients, it should be used with caution in individuals with a history of gastrointestinal disease, particularly colitis, as Clindamycin can cause severe and possibly fatal colitis. Hydrocortisone Acetate should be used with caution in patients with a history of diabetes, glaucoma, or hypertension, as it can exacerbate these conditions.

Patients should also be aware that the use of this formulation can lead to the overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, appropriate measures should be taken. It's also important to note that this medication should only be used for the condition for which it was prescribed, and prolonged use can result in skin thinning and tissue damage.

As compounding pharmacists, we are here to answer any questions you may have about this formulation. Please do not hesitate to reach out to us if you need further information or clarification.

The Clindamycin 50 mg/Hydrocortisone Acetate 90 mg Vaginal Suppository is a solid dosage form that is inserted into the vagina, where it dissolves or melts to release the medication. This formulation is designed for local or systemic absorption, depending on the specific needs of the patient.

Clindamycin is an antibiotic that works by stopping the growth of bacteria. It is used to treat a wide variety of bacterial infections. It is a lincomycin derivative, which works by binding to the 50S subunit of the bacterial ribosome, thus inhibiting protein synthesis in susceptible bacteria. It is effective against Gram-positive aerobes and a wide range of anaerobic bacteria.

Hydrocortisone Acetate, on the other hand, is a corticosteroid that works by reducing inflammation. Corticosteroids are hormones that are naturally produced by the adrenal glands to help suppress bodily inflammation. In medicine, they can be used to help reduce an overactive immune response. Hydrocortisone mimics the action of these hormones and reduces inflammation in the body.

When combined in a vaginal suppository, these two medications can effectively treat a variety of conditions. Clindamycin can help to eliminate any bacterial infections present in the vagina, while Hydrocortisone Acetate can help to reduce any associated inflammation and discomfort. This can be particularly useful in treating conditions such as bacterial vaginosis, where there is an overgrowth of bacteria in the vagina, leading to symptoms such as discharge, itching, and burning.

It's important to note that while this formulation can be very effective, it should only be used under the guidance of a healthcare professional. Misuse or overuse of antibiotics can lead to antibiotic resistance, which can make infections more difficult to treat in the future. Similarly, overuse of corticosteroids can lead to side effects such as skin thinning, easy bruising, changes in body fat (especially in face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

If you have any questions about this formulation, or if you're interested in using it for your patients, please don't hesitate to reach out to us. We're here to help and provide any information you may need.

Clindamycin and Hydrocortisone Acetate are both active ingredients in this vaginal suppository formulation. In addition to its primary use, the formulation can be used to treat varying conditions. Clindamycin, an antibiotic, is mainly used to treat bacterial vaginal infections. However, it can be employed to help manage infections caused by anaerobic bacteria that can lead to conditions such as pelvic inflammatory disease or abdominal infections.

Hydrocortisone Acetate, a topical corticosteroid, is utilized primarily for its anti-inflammatory and immunosuppressive effects. It can be used as part of management strategy for conditions that influence the anal area – such as hemorrhoids or anal fissures, due to its ability to provide symptomatic relief from itching, pain and swelling.

Please note that off-label usage and prescribing should be done only under the strict supervision of a healthcare professional. It is crucial to ensure the right dose and application method are maintained when making use of this formulation for non-primary uses. Inform your healthcare provider about your current list of medications, over the counter products, allergies, pre-existing diseases, and current health conditions before you start using this drug.

Finally, always remember that any kind of medication, including Clindamycin 50mg/Hydrocortisone Acetate 90mg Vaginal Suppository, poses potential risks. Thus, it's always wise to discuss these factors, as well as any questions or concerns, with your healthcare provider before starting the medication. This formulation may have negative interactions with other drugs, exacerbate certain health conditions, or provoke allergic reactions. Hence, if you notice any adverse effect or experience an allergic reaction while using this formulation, seek immediate medical help.

If you require more information about this specialized compounding medication or have further queries, please do not hesitate to contact us at Bayview Pharmacy. With our team of knowledgeable compounding pharmacists, we are well equipped to provide you with the most accurate information.