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Formulas

Clindamycin HCl 1%/Mupirocin 2%/Zinc Oxide 25% Topical Ointment

FDA-approved generic
Dose form
Topical Ointment
Active ingredients
Clindamycin Hydrochloride
Zinc Oxide
Mupirocin Calcium

This formulation is a Clindamycin HCl 1%/Mupirocin 2%/Zinc Oxide 25% Topical Ointment, a semi-solid preparation dispensed in a tube for external application. It is designed to deliver therapeutic agents directly to the skin through its greasy or oily base. The active ingredients in this formulation are Clindamycin HCl, Mupirocin, and Zinc Oxide.

Clindamycin HCl is an antibiotic that fights bacteria in the body, while Mupirocin is used to treat skin infections. Zinc Oxide is a skin protectant that provides a barrier against moisture and irritants, and also promotes wound healing.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clindamycin Hydrochloride
Zinc Oxide
Mupirocin Calcium
Topical Ointment
653eb6af75418fbe674a2c99

Formula Information

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This formulation is a combination of Clindamycin HCl 1%, Mupirocin 2%, and Zinc Oxide 25% in a topical ointment. Clindamycin HCl is an antibiotic that works by stopping the growth of bacteria. It is used to treat a wide variety of bacterial infections. Mupirocin is another antibiotic that prevents bacteria from growing on your skin. It is used to treat certain skin infections such as impetigo or folliculitis. It may also be used to prevent infections in minor cuts, scrapes, or burns.

Zinc Oxide is a mineral that provides a protective barrier on the skin. It is used to treat and prevent diaper rash and other minor skin irritations (e.g., burns, cuts, scrapes). It works by forming a barrier on the skin to protect it from irritants/moisture. The combination of these three active ingredients in a greasy or oily base allows for localized treatment of skin conditions.

Patients using this formulation should apply it to the affected area as directed by their healthcare provider, usually 1 to 3 times daily. It is important to clean and dry the affected area before applying the ointment. The medication should be rubbed in gently and completely. It is important not to use this medication more often or for longer than prescribed by your doctor. This could result in an increased risk of side effects. Also, this medication should not be used on large areas of the body or used for prolonged periods without a doctor's approval.

Prescribers should be aware that this formulation is for external use only and should not be used in the eyes, nose, or mouth. It is also important to note that prolonged use of antibiotics may result in a decrease in their effectiveness and an increase in resistant bacteria. Therefore, this medication should be used for the shortest duration necessary to achieve the desired clinical outcome. If the condition does not improve after a few days or if it worsens, the prescriber should be contacted.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This formulation contains Clindamycin HCl, Mupirocin, and Zinc Oxide, each of which has its own potential for drug interactions. Clindamycin HCl is an antibiotic that works by stopping the growth of bacteria. It may interact with erythromycin, thus it is important to inform your healthcare provider if you are currently using this medication. Concurrent use of these medications may result in decreased effectiveness of one or both drugs.

Mupirocin is another antibiotic that prevents bacteria from growing on your skin. While Mupirocin does not typically interact with oral medications, it is important to inform your healthcare provider of all the products you use, including prescription drugs, nonprescription drugs, and herbal products, as these could potentially affect the efficacy of the Mupirocin.

Zinc Oxide is a skin protectant that provides a barrier against irritants and helps in wound healing. It is generally considered safe and does not typically interact with other medications. However, it is still important to inform your healthcare provider of all the products you use, including prescription drugs, nonprescription drugs, and herbal products.

This formulation is designed to treat skin inflammation, infections, and aid in wound healing. Clindamycin HCl and Mupirocin work together to combat bacterial infections on the skin, while Zinc Oxide provides a protective barrier to promote healing and prevent further irritation. It is important to use this medication as directed by your healthcare provider, and to complete the full course of treatment, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

As with all medications, this formulation may cause side effects, including burning, itching, dryness, redness, oily skin, skin peeling, or irritation at the application site. If any of these effects persist or worsen, notify your healthcare provider promptly. Remember that your healthcare provider has prescribed this medication because they have judged that the benefit to you is greater than the risk of side effects.

If you have any questions about this formulation or its potential interactions with other medications or products, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

How Does it Work

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This formulation combines three active ingredients: Clindamycin HCl, Mupirocin, and Zinc Oxide, each with a unique mechanism of action to treat various skin conditions. Clindamycin HCl is an antibiotic that works by stopping the growth of bacteria. By inhibiting protein synthesis in these bacteria, Clindamycin HCl prevents them from growing and multiplying, thereby helping to clear the infection.

Mupirocin is another antibiotic in this formulation, but it works differently from Clindamycin HCl. It inhibits the enzyme isoleucyl-tRNA synthetase, which is essential for bacterial protein synthesis. This action prevents the bacteria from producing proteins that are necessary for their growth and reproduction.

Zinc Oxide is a skin protectant with astringent, soothing, and protective properties. It forms a physical barrier on the skin, protecting it from irritants and promoting healing. Zinc Oxide also has mild antiseptic properties, which can help prevent infection in minor wounds and burns. Furthermore, it can soothe and reduce inflammation and irritation in various skin conditions, such as diaper rash, minor burns, severely chapped skin, or other minor skin irritations.

The semi-solid base of this formulation aids in the delivery of these active ingredients to the skin. It provides a greasy or oily layer that helps to keep the skin moisturized, which can promote healing and improve the effectiveness of the active ingredients. This formulation is designed for external application to the skin and should not be used on large areas of the body, in the eyes, or inside the nose or mouth.

Overall, this formulation provides a comprehensive approach to treating various skin conditions. The combination of two antibiotics helps to clear bacterial infections, while the Zinc Oxide protects the skin and promotes healing. However, as with any medication, it is important to use this formulation as directed by a healthcare provider to ensure its safety and effectiveness. If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy.

Other Uses

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The Clindamycin HCl 1%/Mupirocin 2%/Zinc Oxide 25% Topical Ointment is traditionally formulated for the treatment of skin infections and inflammation, as well as fostering wound healing. However, it offers a broad range of alternative therapeutic benefits. Clindamycin, an antibiotic, can also help treat severe cases of acne, either presented alone or as a combination acne therapy. Mupirocin, another antibiotic, can function independently to eradicate certain nasal bacteria, acting to minimize the risk of bacterial spread within a group or household setting.

Zinc Oxide, on the other hand, serves as a skin protectant and mild astringent with some antiseptic action. This makes it a valuable component in addressing minor skin discomforts like burns, chafing, diaper rash, and other skin irritations. It can also serve as a barrier cream, providing protection and potential relief for Individuals with certain skin conditions, including those resulting from incontinence or ostomy creation. It is also utilized for sunburns, or as a mild sun protectant for those hypersensitive to other sunscreen ingredients.

This multi-component formulation offers the option of tackling more than one skin concern simultaneously, thereby providing both antimicrobial and soothing properties. It is important to monitor for potential sensitivities to any of the components, particularly in those with known allergies to similar compounds. Overuse or misuse can lead to increased bacterial resistance. Always follow the application guidelines provided by your healthcare professional, and report any unusual or severe skin reactions immediately.

While this represents a brief overview of potential other uses, it is essential to keep subjective health condition, bacterial strain, and unique treatment protocol into account. We recommend that prescribers use this formulation as a versatile tool within their treatment options, and patients diligently follow the application and dosage instructions to reap full therapeutic benefits. If you need more information or have questions related to personalized advice or alterations in the formulation, feel free to reach out to our team of compounding pharmacists at Bayview Pharmacy. We are dedicated to applying our knowledge skillfully for individualized patient care.

Frequently Asked Questions

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What is Clindamycin HCl 1%/Mupirocin 2%/Zinc Oxide 25% Topical Ointment used for?

This compounded formulation is intended for localized treatment, specifically for conditions such as skin inflammations, infections, or assisting in wound healing.

How should I apply this ointment?

Apply a thin layer of the ointment topically on the skin, specifically on the affected area as directed by your healthcare provider. It is typically used for external application only.

What does the greasy or oily base do?

The greasy or oily base aids in the delivery of the medication or therapeutic agents, allowing them to permeate the skin efficiently.

What is the purpose of Zinc Oxide in the formulation?

Zinc Oxide is known for its skin-protective properties. It offers a barrier layer that can help protect the skin and aid in wound healing.

What does Clindamycin HCl do in this formulation?

Clindamycin HCl is an antibiotic that works to prevent bacterial growth, thereby treating skin infections.

What role does Mupirocin play in the ointment?

Mupirocin is an antibiotic that prevents the growth of bacteria on the skin. It assists in the treatment of skin infections by working together with Clindamycin HCl.

How often should I use this ointment?

The frequency of use should be determined by your physician or a healthcare professional. Always follow their instructions on how much and how often to apply the ointment.

What are the possible side effects of this topical ointment?

Like all medications, this ointment can cause side effects. Common ones may include skin dryness, redness, or itching. If these persist or worsen, immediately contact your healthcare provider.

Can this ointment be used on open wounds?

Yes, this formulation can be used for wound healing. However, care should be taken and it is strongly advised to consult with your healthcare provider before applying the ointment on open wounds.

Is the ointment safe for all skin types?

While it is designed to be beneficial for many conditions, individual reactions can vary. Thus, it is important to consult your healthcare provider to ensure it is safe and suitable for your specific skin type. If you notice any adverse reactions, stop use immediately and consult with your healthcare provider.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clindamycin HCl 1%/Mupirocin 2%/Zinc Oxide 25% Topical Ointment
Topical Ointment
30 g
controlled

Apply topically to affected area(s)