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Clotrimazole 1%/Urea 20% Topical Ointment

Clotrimazole 1%/Urea 20% Topical Ointment is a semi-solid formulation dispensed in a tube for external application. This ointment provides a greasy or oily base that aids in the delivery of the active ingredients, clotrimazole and urea, for localized treatment. Clotrimazole is an antifungal medication used to treat skin infections, while urea is a keratolytic agent that helps to soften and remove rough, scaly skin. This formulation is typically used for conditions such as skin inflammation, infections, or wound healing.

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Topical Ointment
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Formula Information

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This formulation combines Clotrimazole 1% and Urea 20% in a topical ointment designed for external application to the skin. The semi-solid formulation is dispensed in a tube and provides a greasy or oily base that aids in the delivery of the medication or therapeutic agents for localized treatment. This formulation is typically used for conditions such as skin inflammation, infections, or wound healing.

Clotrimazole is an antifungal medication that works by stopping the growth of fungus. It is used to treat skin infections such as athlete's foot, jock itch, ringworm, and other fungal skin infections (candidiasis). This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs.

Urea is used to treat dry/rough skin conditions (e.g., eczema, psoriasis, corns, callus) and some nail problems (e.g., ingrown nails). It can also be used to help remove dead tissue in some wounds to help wound healing. Urea works by increasing the amount of moisture in the skin by softening/dissolving the horny substance (keratin) holding the top layer of skin cells together. This helps the dead skin cells fall off and helps the skin keep more water in, reducing itchy and flaky skin.

Together, Clotrimazole and Urea in this formulation work synergistically to treat and manage skin conditions by addressing both the infection and the skin's condition. The greasy or oily base of the ointment aids in the delivery of these therapeutic agents, ensuring that they are effectively absorbed into the skin for optimal treatment.

It is important to note that this medication should be used as directed by a healthcare professional. The area of application should be clean and dry before application. The medication should be applied in a thin layer and rubbed in gently. Avoid contact with the eyes, nose, mouth, and other sensitive areas. If irritation or sensitivity develops with the use of this medication, discontinue use and consult a healthcare professional.

If you have any questions about this formulation, its use, or any other concerns, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to assist you.

Drug Interactions

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Clotrimazole 1%/Urea 20% Topical Ointment is a combination medication used to treat a variety of skin conditions. Clotrimazole is an antifungal medication that works by stopping the growth of fungus, while Urea is a keratolytic agent that works by increasing the moisture in the skin and breaking down hard, scaly, or rough skin.

While this formulation is generally safe and effective, it's important to be aware of potential drug interactions. Certain medications may interact with Clotrimazole/Urea Topical Ointment, potentially altering its effectiveness or increasing the risk of side effects. For instance, using this ointment with other topical medications, especially those containing corticosteroids, may increase the risk of skin thinning or other side effects.

Additionally, using this ointment with other products that can cause skin irritation such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime should be avoided. It's also important to avoid using bandages, dressings, or plastic wrap on treated skin areas unless directed by a healthcare provider.

It's crucial to inform your healthcare provider about all the products you use, including prescription drugs, nonprescription drugs, and herbal products, before starting treatment with Clotrimazole/Urea Topical Ointment. This will help your healthcare provider to monitor for drug interactions and manage them appropriately.

Patients should also be aware that this medication should not be used on the face, underarms, or groin areas unless directed by a healthcare provider. If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your healthcare provider the potential risks and benefits of using this medication.

Clotrimazole/Urea Topical Ointment is typically used for conditions such as skin inflammation, infections, or wound healing. By combining the antifungal properties of Clotrimazole and the keratolytic properties of Urea, this formulation can effectively treat a variety of skin conditions, providing relief from symptoms and promoting healing.

If you have any questions about Clotrimazole/Urea Topical Ointment, its potential drug interactions, or how it treats specific disease states, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

How Does it Work

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The Clotrimazole 1%/Urea 20% Topical Ointment is a semi-solid formulation that is designed for external application to the skin. It is dispensed in a tube and provides a greasy or oily base that aids in the delivery of medication or therapeutic agents for localized treatment. This formulation is typically used for conditions such as skin inflammation, infections, or wound healing.

Clotrimazole, the first active ingredient in this formulation, is an antifungal medication that works by inhibiting the growth of fungus. It does this by interfering with the production of the fungal cell membrane. The cell membrane is crucial for the survival of the fungus, and by disrupting its production, clotrimazole causes the fungal cells to become unstable and eventually die, thereby treating the infection.

The second active ingredient, Urea, is a keratolytic. It works by increasing the moisture in the skin and breaking down the hard, scaly, or crusty skin tissue. This helps to speed up the shedding of dead skin cells, softens the skin, and aids in the absorption of the clotrimazole into the skin. This dual-action of urea not only helps to treat the infection but also promotes the healing of the skin.

Together, these two active ingredients work synergistically to treat skin infections and promote healing. The greasy or oily base of the ointment also helps to protect the skin and lock in moisture, further aiding in the healing process. It is important to note that while this formulation can provide significant relief from symptoms, it is not a cure for the underlying cause of the infection. Therefore, it is crucial to use this medication as directed by a healthcare provider and to complete the full course of treatment, even if symptoms improve before the treatment is finished.

If you have any questions about this formulation, how it works, or how to use it, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

Other Uses

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Clotrimazole 1%/Urea 20% Topical Ointment is typically indicated for the treatment of various inflammatory skin conditions, infections, and aiding in wound healing. However, this formulation also has potential uses beyond its conventional applications. Clotrimazole, an antifungal agent, can be beneficial in managing various types of cutaneous fungal infections such as candidiasis, ringworm, athlete's foot, jock itch and other similar conditions. It has the ability to halt the growth of the fungus by interfering with their cell membranes. The Urea component, on the other hand, is a keratolytic agent that can soften the skin and enhance its ability to absorb and retain moisture.

Given these properties, this ointment could thus be used as a part of the treatment regimen for various types of dermatitis, psoriasis, and dry, rough, or hardened skin, as well as certain types of eczema. It can also provide relief from symptoms linked with these conditions such as itching, burning, and discomfort. As Urea breaks down and loosens dead skin, it can enhance the effectiveness of other skin treatments by promoting better absorption of other medications.

For prescribers, it is always crucial to consider the patient's overall health status, existing medical conditions, and currently used medications before recommending Clotrimazole 1%/Urea 20% Topical Ointment for these other uses. Potential interactions as well as possible side effects such as skin irritation, redness or itching should be discussed with the patient. As always in the field of medicine, the benefits must outweigh the potential risks before a directed treatment is planned.

For patients, it is of great significance to follow the usage instructions provided by your healthcare professional or pharmacist. Do not use this product for longer periods than instructed or apply more than the recommended amount, as it can lead to unnecessary side effects. The area to which the ointment has been applied should not be covered with bandages or other dressings unless directed by the healthcare professional. If you notice any severe or disconcerting side effects while using the ointment, seek immediate medical attention.

If there are any queries or concerns, do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists will be more than willing to assist with any questions or seek additional information for prescribers, to ensure that you are given the best treatment approach possible.

Frequently Asked Questions

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What is Clotrimazole 1%/Urea 20% Topical Ointment?

This is a semi-solid formulation that is designed for external application to the skin. It contains two active ingredients Clotrimazole and Urea at 1% and 20% respectively. The ointment provides a greasy or oily base that aids in the delivery of these medications for localized treatment.

What conditions can Clotrimazole 1%/Urea 20% Topical Ointment be used to treat?

This compounded formulation is typically used for conditions such as skin inflammation, infections, or wound healing where a localized treatment is required.

How is Clotrimazole 1%/Urea 20% Topical Ointment applied?

The ointment is applied externally to the skin. It is dispensed in a tube, making application easy.

What are Clotrimazole and Urea used for?

Clotrimazole is an antifungal medication, usually used to treat various kinds of fungal infections. Urea is a compound that is used to promote healing of certain skin conditions and to soften and remove damaged or diseased skin.

Why is the ointment greasy or oily?

The greasy or oily base of the ointment aids in the delivery of the active ingredients, Clotrimazole and Urea. It facilitates penetration of these into the skin for effective localized treatment.

Are there any side effects of using Clotrimazole 1%/Urea 20% Topical Ointment?

Any medication can have potential side effects, and these can vary from person to person. Common side effects might include skin irritation, redness, or a stinging sensation on application. If you experience any worrying side effects, please contact your healthcare professional promptly.

Can I use other skincare products following the application of the ointment?

It is advisable to discuss this with your healthcare provider. The ointment's greasy or oily base may interact with other skincare products, potentially impacting the effectiveness of either treatment.

How often should I apply Clotrimazole 1%/Urea 20% Topical Ointment?

The frequency of application will depend on the specific condition being treated and should be defined by your healthcare provider.

How should I store Clotrimazole 1%/Urea 20% Topical Ointment?

The best storage conditions for this formulation will typically be in a cool, dry place, away from direct sunlight. Please refer to the product packaging for specific storage instructions.

Can Clotrimazole 1%/Urea 20% Topical Ointment be used by everyone?

This ointment is generally safe for most people to use. However, it is essential to discuss your medical history and any current medications or underlying health conditions with your healthcare provider before starting any new treatment.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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