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Clotrimazole 10%/Urea 20% Topical Lotion

This formulation is a Clotrimazole 10%/Urea 20% Topical Lotion, a liquid or semi-liquid preparation intended for external application to the skin. It is characterized by its smooth and spreadable consistency, which not only provides moisturizing and soothing effects but also promotes the absorption of the active ingredients for localized treatment.

The active ingredients, Clotrimazole and Urea, work synergistically to treat specific skin conditions. Clotrimazole, an antifungal medication, is effective in treating various fungal infections, while Urea, a keratolytic, helps to soften and remove rough, scaly skin.

This formulation is particularly beneficial in treating conditions such as ringworm, athlete's foot, jock itch, and nail fungus. It is also used to manage dry, rough skin conditions like psoriasis, eczema, corns, callus, and some other types of dermatitis. The lotion's therapeutic effects are localized, targeting the specific area of application for optimal results.

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Topical Lotion
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Formula Information

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This formulation combines Clotrimazole 10% and Urea 20% in a topical lotion designed for external application to the skin. Clotrimazole is an antifungal medication that works by stopping the growth of fungus, making it effective in treating a variety of fungal skin infections such as ringworm, athlete's foot, and jock itch. It can also be used to treat yeast infections of the skin. Urea is a keratolytic, which means it softens and removes rough, scaly, or hardened skin. It is often used to treat conditions like dry/rough skin, psoriasis, eczema, corns, callus, and some nail problems.

The lotion form of this medication is designed to be smooth and spreadable, making it easy to apply to the affected areas of the skin. It also offers moisturizing and soothing effects, which can help to alleviate symptoms of dryness, itching, and irritation often associated with these skin conditions. The lotion promotes absorption of the active ingredients, allowing for localized treatment of the affected areas.

Patients using this formulation should apply it as directed by their healthcare provider, typically to the affected skin and the surrounding area. It is important to clean and dry the area before applying the lotion. The medication should be used regularly to get the most benefit from it, and it is important to continue using it for the full prescribed length of time, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Prescribers should be aware that some patients may experience mild burning, stinging, or redness when first applying the lotion. If these effects persist or worsen, the patient should be advised to stop using the medication and seek medical attention. It is also important to advise patients to avoid getting the lotion in the eyes, nose, or mouth. If the lotion is accidentally ingested or applied to these areas, the patient should rinse thoroughly with water.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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Clotrimazole 10%/Urea 20% Topical Lotion is a specially compounded formulation designed to treat a variety of skin conditions. Clotrimazole is an antifungal medication that works by inhibiting the growth of fungus, while urea is a keratolytic agent that helps to soften and remove dead skin cells. This combination is particularly effective in treating fungal skin infections, such as ringworm, athlete's foot, and jock itch, as well as conditions like psoriasis and eczema where excessive skin build-up is a problem.

While this formulation is generally safe and effective, it's important to be aware of potential drug interactions. Clotrimazole, when used topically, is not likely to interact with many medications due to its limited systemic absorption. However, it's always important to inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs and herbal supplements. This is to ensure that any potential interactions can be identified and managed appropriately.

Urea, on the other hand, can potentially interact with certain topical medications. For instance, using urea in combination with other topical medications that increase skin exfoliation, such as salicylic acid or alpha hydroxy acids, may lead to increased skin irritation. Therefore, it's recommended to use caution when using this formulation in combination with other topical treatments.

Additionally, while urea is generally well-tolerated, it can cause skin irritation in some individuals, particularly those with sensitive skin. If you experience any signs of skin irritation, such as redness, itching, or burning, discontinue use and contact your healthcare provider.

It's also important to note that while this formulation can be highly effective in treating certain skin conditions, it should not be used on broken or infected skin, unless directed by a healthcare provider. This is because the urea component can potentially increase absorption of clotrimazole, leading to increased risk of systemic side effects.

As compounding pharmacists, we are here to answer any questions you may have about this formulation. Whether you're a patient or a prescriber, don't hesitate to reach out to us for more information. We're committed to ensuring that you have all the information you need to use this formulation safely and effectively.

How Does it Work

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Clotrimazole 10%/Urea 20% Topical Lotion is a specially formulated medication designed to treat a variety of skin conditions. The lotion is a liquid or semi-liquid formulation that is applied externally to the skin. It has a smooth and spreadable consistency, which allows for easy application and absorption. The lotion not only provides moisturizing and soothing effects, but also delivers therapeutic benefits through its active ingredients, clotrimazole and urea.

Clotrimazole is an antifungal medication that works by inhibiting the growth of fungus. It does this by interfering with the production of the fungal cell membrane. The cell membrane is crucial for the survival and growth of the fungus. When clotrimazole disrupts its production, it causes the contents of the fungal cells to leak out, which ultimately leads to their death. This effectively treats and prevents fungal infections on the skin.

Urea, on the other hand, is a keratolytic agent. It works by increasing the moisture in the skin and breaking down the hard, scaly skin. Urea causes the skin cells to shed, which helps soften and remove the dead skin. This action of urea helps in promoting the absorption of clotrimazole into the skin, making the treatment more effective.

This combination of clotrimazole and urea in a lotion form is particularly effective in treating skin conditions such as ringworm, athlete's foot, jock itch, and fungal infections. The urea in the formulation helps to soften the hard, scaly skin often associated with these conditions, allowing the clotrimazole to penetrate more effectively and treat the underlying fungal infection.

It's important to note that while this lotion provides relief from symptoms and treats the infection, it may not cure the underlying cause of the skin condition. Therefore, it's crucial to consult with a healthcare provider for a complete diagnosis and treatment plan. As compounding pharmacists, we are here to answer any questions you may have about this formulation. Please don't hesitate to reach out to us.

Other Uses

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Clotrimazole 10%/Urea 20% Topical Lotion is primarily used for the treatment of fungal skin infections, keratolytic conditions, diseased nails, and other relevant skin conditions. However, it has also found applicability in other instances. The anti-fungal property of Clotrimazole makes it a suitable option for treating not just a wide range of skin infections caused by fungi such as tinea corporis, tinea cruris, tinea pedis, but also for conditions such as pityriasis versicolor, and candidiasis that affects the skin.

Urea in the formulation acts as a keratolytic and hydrating agent, aiding in the softening and breakdown of keratin, a substance that forms part of the skin structure. This makes the formulation effective in treating conditions such as psoriasis, ichthyosis, eczema, corns, callus, and other conditions of hyperkeratosis where there is an abnormal thickening of the skin layer. It can also be utilized as a moisturizing agent for skin that is excessively dry or rough.

Additionally, this combined formulation can be beneficial in treating onychomycosis, a fungal infection that affects the nails. Here, Urea aids in the softening and thinning of the affected nail, thereby enhancing the penetration of Clotrimazole to effectively target the fungal infections.

Although this formulation is generally safe, it's important for patients to apply it correctly and avoid contact with the eyes, nose, and mouth. As with any medication, potential side effects may occur, such as skin irritation, redness, burning, or itching. It is imperative for prescribers to assess the suitability of this formulation on a case-by-case basis, considering the patient's overall health status, concurrent medications, and potential for allergic reactions. While using this formulation, care should be taken to avoid any likely areas of open wounds or sores.

Remember, though Clotrimazole 10%/Urea 20% Topical Lotion has versatile uses, it should only be used under medical supervision. Unsupervised or prolonged use can result in resistance or unwanted side effects. If you have any further questions or concerns, please do not hesitate to reach out to us.

Frequently Asked Questions

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What is Clotrimazole 10%/Urea 20% Topical Lotion?

Clotrimazole 10%/Urea 20% Topical Lotion is a liquid or semi-liquid formulation designed for external application to the skin. This formulation is designed to offer moisturizing, soothing, or therapeutic effects for specific skin conditions, while promoting absorption of active ingredients for localized treatment.

What are the active ingredients in this lotion?

The active ingredients in this topical lotion are clotrimazole and urea. Clotrimazole is an antifungal medication that treats skin infections caused by fungus, while urea aids in hydration and removal of dead skin cells.

How should I apply this lotion?

You should apply this lotion topically, as directed by your healthcare provider. Typically, it is applied to the affected area in a thin layer and rubbed gently until absorbed.

Can I use this lotion on my face?

You should only use this lotion on your face if directed by your healthcare provider. Avoid contact with eyes, nose, or mouth.

Does this lotion have any side effects?

As with any medication, this lotion can have side effects. These may include redness, stinging, blistering, peeling, swelling, itching, burning, or irritation where the medicine is applied. If you experience any of these symptoms, contact your healthcare provider.

Can I use this lotion while pregnant?

Before using this lotion, tell your healthcare provider if you are pregnant or plan to become pregnant. While clotrimazole and urea are generally considered safe for use during pregnancy, only use this product if clearly needed and under the supervision of a healthcare provider.

Is this lotion suitable for children?

The safety and effectiveness of this lotion in children have not been established. It should only be used in children if directed by a healthcare provider.

What should I do if I miss a dose?

If you miss a dose, apply the lotion as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to make up for a missed one.

Can I use this lotion with other skin products?

Before using other skin products on the area treated with this lotion, discuss with your healthcare provider as they may interfere with the absorption of the medication or increase the risk of side effects.

How should I store this lotion?

Keep this lotion in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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