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Clotrimazole 10%/Urea 20% Topical Ointment

FDA-approved generic
Dose form
Topical Ointment
Active ingredients
Clotrimazole
Urea

The Clotrimazole 10%/Urea 20% Topical Ointment is a semi-solid formulation dispensed in a tube, specifically designed for external application to the skin. This ointment provides a greasy or oily base that aids in the delivery of the active ingredients, clotrimazole and urea, for localized treatment.

Clotrimazole is an antifungal medication that treats skin infections caused by fungus, while urea is a keratolytic agent that helps to soften and remove rough, scaly skin.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clotrimazole
Urea
Topical Ointment
653ec2bb4d7e94d29e174c9e
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation combines Clotrimazole 10% and Urea 20% in a topical ointment designed for external application to the skin. The semi-solid formulation is dispensed in a tube and provides a greasy or oily base that aids in the delivery of the medication or therapeutic agents for localized treatment. This formulation is typically used for conditions such as skin inflammation, infections, or wound healing.

Clotrimazole is an antifungal medication that works by stopping the growth of fungus. It is used to treat skin infections such as athlete's foot, jock itch, ringworm, and other fungal skin infections (candidiasis). This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs.

Urea is used to treat dry/rough skin conditions (e.g., eczema, psoriasis, corns, callus) and some nail problems (e.g., ingrown nails). It can also be used to help remove dead tissue in some wounds to help wound healing. Urea is known as a keratolytic. It increases moisture in the skin by softening/dissolving the horny substance (keratin) holding the top layer of skin cells together. This effect helps the dead skin cells fall off and helps the skin keep more water in, leading to softer skin and faster healing.

Together, Clotrimazole and Urea in this formulation work synergistically to treat fungal skin infections while promoting skin healing and softening. The greasy or oily base of the ointment aids in the delivery of these therapeutic agents, ensuring they are effectively absorbed into the skin for localized treatment.

The duration of treatment depends on the type of infection being treated. It is also crucial to continue using this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow the fungus to continue to grow, which may result in a return of the infection.

If you have any questions about this formulation, its uses, or its application, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to assist you.

Drug Interactions

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Clotrimazole 10%/Urea 20% Topical Ointment is a combination medication used to treat various skin conditions. Clotrimazole is an antifungal medication that works by stopping the growth of fungus, while Urea is a keratolytic that works by increasing the moisture in the skin and breaking down dead skin cells. This combination is typically used to treat conditions such as skin inflammation, infections, or wound healing.

While Clotrimazole/Urea Topical Ointment is generally safe for use, it's important to be aware of potential drug interactions. Clotrimazole may interact with other topical medications, particularly those that also have antifungal properties. Using multiple antifungal treatments concurrently may increase the risk of side effects and reduce the effectiveness of the medications. Therefore, it's important to inform your healthcare provider of all the products you use, including prescription drugs, nonprescription drugs, and herbal products, before starting treatment with this medication.

Urea, on the other hand, may interact with certain medications that are designed to increase skin exfoliation, such as retinoids, alpha hydroxy acids, and salicylic acid. Using these medications together with Urea may increase the risk of skin irritation. Therefore, it's important to inform your healthcare provider if you are using any products that contain these ingredients.

Furthermore, this medication should not be used on broken or infected skin unless directed by a healthcare provider, as it may worsen the condition or lead to unwanted side effects. It's also important to avoid getting this medication in your eyes, nose, or mouth. If this happens, rinse thoroughly with water.

As with any medication, it's important to use Clotrimazole/Urea Topical Ointment as directed by your healthcare provider. Do not use more of this medication, use it more often, or use it for a longer time than prescribed. Your condition will not improve faster, and your risk of side effects may increase.

If you have any questions about Clotrimazole/Urea Topical Ointment, its uses, or potential drug interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

How Does it Work

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The Clotrimazole 10%/Urea 20% Topical Ointment is a semi-solid formulation designed for external application to the skin. It is dispensed in a tube and provides a greasy or oily base that aids in the delivery of medication or therapeutic agents for localized treatment. This formulation is typically used for conditions such as skin inflammation, infections, or wound healing.

Clotrimazole, the first active ingredient in this formulation, is an antifungal medication that works by inhibiting the growth of fungus. It does this by interfering with the production of the fungal cell membrane. The cell membrane of a fungus is crucial for its survival, as it prevents the cell from losing essential components and protects it against the external environment. By disrupting the production of the cell membrane, clotrimazole causes the fungal cells to leak and die, thereby treating the infection.

The second active ingredient, Urea, is a keratolytic agent. Keratolytics work by softening and breaking down the outermost layer of the skin, known as the stratum corneum. This allows for the shedding of scaly skin, promotes the healing of the skin underneath, and improves the penetration of the clotrimazole into the skin. Urea also has humectant properties, meaning it can attract and retain moisture in the skin, which helps to hydrate and soften the skin, reducing itching and flaking.

Together, these two ingredients work synergistically to treat skin conditions. The Urea softens and hydrates the skin, allowing the Clotrimazole to penetrate more effectively and treat the underlying fungal infection. This formulation is particularly useful for conditions where the skin is thickened or scaly, as the Urea can help to break down this barrier and allow the Clotrimazole to reach the site of infection.

Overuse or misuse can lead to skin irritation or other side effects. If you have any questions about this formulation, or if you're unsure whether it's right for you, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

Other Uses

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Clotrimazole 10%/Urea 20% Topical Ointment is primarily prescribed for treating skin conditions such as fungal infections, dermatitis, and other inflammatory skin diseases. However, it has additional applications which can be beneficial in a range of other circumstances. Patients experiencing psoriasis, a condition characterized by an accelerated skin cell life cycle causing red patches and scales, may find relief by application of this formulation, as its urea component acts as a keratolytic, helping to soften and shed the excessive skin. Clotrimazole, with its strong anti-fungal properties, may also help alleviate symptoms of other fungal diseases such as tinea infections (jock itch, athlete's foot, and ringworm).

This compound can also be used to treat hyperkeratotic conditions, where the skin becomes excessively hard or thick. The high concentration of urea hydrates and helps to remove dead skin cells, which can help with conditions such as corns, calluses and keratosis. Although not its primary function, it can potentially be used cautiously and sparingly for off-label purposes such as seborrheic dermatitis, intertrigo, and certain nail fungus cases, although this should always be under the strict supervision of a healthcare provider.

Additionally, the urea component can also elevate the penetration of other drugs or ingredients that are used in combination, which makes it an excellent candidate for a multitasking ointment. While this formulation is generally well-tolerated, it may produce side effects such as skin irritation, burning, or stinging in some patients. Always consult your healthcare provider or pharmacist regarding any concerns related to medication usage.

If you or your prescriber have any further questions on this formulation or its applications, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of experienced compounding pharmacists is always ready to provide insight and guidance. It's important to remember that while we make every effort to provide comprehensive and current information, our suggestions should never replace professional medical advice.

Frequently Asked Questions

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What is Clotrimazole 10%/Urea 20% Topical Ointment?

It is a semi-solid formulation, dispensed in a tube, designed for external application to the skin. This ointment is specially compounded with the active ingredients Clotrimazole and Urea. It aids in the delivery of these medications for the treatment of localized skin conditions.

What is the purpose of the oily or greasy base in this formulation?

The greasy or oily base serves as a vehicle for the therapeutic agents, Clotrimazole and Urea. It aids in the delivery of these medications, ensuring they are fully absorbed into the skin for maximum effectiveness.

What skin conditions can this ointment be used for?

This ointment is typically used for conditions such as skin inflammation, infections or wound healing. It might be particularly beneficial for fungal infections of the skin due to the presence of Clotrimazole.

How should Clotrimazole 10%/Urea 20% Topical Ointment be applied?

The ointment should be applied as directed by your healthcare provider, typically onto the affected areas of the skin. It is important to follow the instructions on the label, or as prescribed by your pharmacist or doctor.

What is the role of Clotrimazole in this formulation?

Clotrimazole is an antifungal agent that helps in treating fungal infections by preventing the growth of fungus. The inclusion of this ingredient makes the ointment highly beneficial for treating skin conditions caused by fungus.

What is the role of Urea in this ointment?

Urea is a keratolytic agent. It helps to moisturize the skin and promotes the shedding of dead skin cells. This aids in the treatment of dry, rough and scaly skin conditions and helps wounds to heal.

Is Clotrimazole 10%/Urea 20% Topical Ointment safe for all skin types?

While the ointment is generally safe for most skin types, individuals with hypersensitivity to Clotrimazole, Urea, or any other component of the formulation should avoid its use. It's always best to discuss with your healthcare provider if you have any concerns.

Are there any side effects associated with this ointment?

Side effects can occur with any medication. Some common side effects may include skin irritation, redness or peeling. If you experience severe or worrying side effects, it is advised to consult your healthcare provider immediately.

Can I use this ointment with other skincare products?

It's important to discuss this with your healthcare provider as certain products may interfere with the effectiveness of the ointment. Generally, other skincare products should be applied only after the ointment has fully absorbed into the skin.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not use extra ointment to catch up.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clotrimazole 10%/Urea 20% Topical Ointment
Topical Ointment
30 g
controlled

Apply topically to affected area(s)

Twice daily