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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Prepared to a prescriber's order for one patient. Not FDA-approved.
This is a compounded suppository containing dexamethasone, prepared to a prescriber's order for one patient. Compounded preparations are not FDA-approved.
These listings cover every salt or ester form of each drug in the FDA National Drug Code Directory.
FDA-approved products containing dexamethasone are listed in tablet, injection, suspension, ointment, elixir and solution forms. No dexamethasone product of any kind is listed in suppository form.
Suppository bases differ, and the base used decides how USP <795> classifies the preparation for beyond-use dating. The date printed on the label is the one to follow.
Dexamethasone is a long-acting synthetic corticosteroid, manufactured as oral tablets, solution and other products, that compounding pharmacies prepare in oral, topical and other forms.
Dexamethasone is a synthetic glucocorticoid, a lab-made version of the cortisol-type hormones the adrenal glands produce. It is used mainly for its anti-inflammatory and immune-modifying effects, and at doses with the same anti-inflammatory effect as hydrocortisone it has almost no salt-retaining activity. Manufactured dexamethasone tablets and oral solution are FDA-approved for a long list of conditions across many body systems, including severe allergic conditions, certain skin, rheumatic, blood, eye, respiratory, kidney and digestive diseases, adrenal insufficiency (where hydrocortisone is preferred), palliative management of some leukemias and lymphomas, cerebral edema, and diagnostic testing of adrenal overactivity. Prescribers may order dexamethasone compounded when they want a strength or concentration that is not manufactured, a liquid or topical form, a preparation free of dyes, sugar or another excipient, or a combination with another ingredient. Compounded dexamethasone is not FDA-approved and requires a prescription.
Manufactured oral dexamethasone carries no boxed warning. It is contraindicated in systemic fungal infections and in anyone allergic to it. Because corticosteroids suppress the body's own cortisol production, do not stop it suddenly after longer courses; your prescriber will taper it. It raises infection risk and can hide the signs of one, and live vaccines should not be given during immunosuppressive doses. Other warnings include high blood sugar, fluid retention and high blood pressure, low potassium, bone loss and growth slowing in children, stomach ulcers, and mood changes, insomnia or psychosis. It interacts with CYP3A4 inducers such as phenytoin and rifampin, inhibitors such as ketoconazole, warfarin, diabetes medicines, and potassium-depleting diuretics. Use in pregnancy only when benefit outweighs risk. LactMed states short-term use is unlikely to affect a breastfed infant. For fever, black stools, vision changes or unusual weakness, talk to your prescriber or pharmacist.
Dexamethasone is a synthetic glucocorticoid with a relative anti-inflammatory potency about 25 times that of hydrocortisone, classed as a long-duration agent, with negligible mineralocorticoid activity at equipotent doses. Glucocorticoids are readily absorbed from the gastrointestinal tract; metabolic clearance falls in cirrhosis, and dexamethasone is itself a moderate CYP3A4 inducer, so inducers and inhibitors of CYP3A4 alter its exposure. The tablet and oral solution labels list indications spanning allergic, dermatologic, endocrine, rheumatic, hematologic, neoplastic, nervous system, ophthalmic, renal, respiratory and gastrointestinal categories, plus diagnostic testing for adrenocortical hyperfunction. Prescribers have ordered compounded dexamethasone oral suspensions when a dye-free or specific-concentration liquid is needed; published stability studies describe suspensions prepared from tablets or powder in commercial suspending vehicles, and one pediatric study designed a suspension free of potentially harmful excipients. Dosing, duration and taper per prescriber. Monitoring per label: blood pressure, glucose, electrolytes including potassium, weight and edema, intraocular pressure if therapy exceeds six weeks, linear growth in children, bone health with prolonged use, coagulation with warfarin, and signs of adrenal insufficiency on withdrawal; infants exposed in utero should be observed for hypoadrenalism. Not a controlled substance.
Wash your hands. If the suppository is soft, chill it in its wrapper in the refrigerator or under cool water for a few minutes, then unwrap it. For rectal use, coat the tip with a water-soluble lubricant (not petroleum jelly), lie on your side with your upper knee bent, and insert it pointed end first past the muscle at the opening. For vaginal use, lie on your back with knees bent and insert it as far as it comfortably goes, by finger or applicator; bedtime use limits leakage, and a panty liner protects clothing. Stay lying down about 15 minutes. Wash your hands.
Suppositories are nonaqueous, so under USP <795> they can carry a beyond-use date of up to 180 days at controlled room temperature or in the refrigerator when no other stability data apply. Storage depends on the base: fatty bases can soften at room temperature and may be labeled for the refrigerator, while polyethylene glycol bases usually do not need refrigeration. Keep them cool so they do not melt, and refrigerate them if your label says to.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert 1 unwrapped suppository
