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Dihydroergotamine Mesylate 5 mg/Promethazine HCl 50 mg/Caffeine 100 mg Suppository

FDA-approved generic
Dose form
Suppository
Active ingredients
Dihydroergotamine Mesylate
Promethazine Hydrochloride
Caffeine

Bayview Pharmacy's Dihydroergotamine Mesylate 5 mg/Promethazine HCl 50 mg/Caffeine 100 mg Suppository is a solid dosage form designed for insertion into a body cavity, typically the rectum or vagina. Upon dissolution or melting, it releases medication for local or systemic absorption.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Dihydroergotamine Mesylate
Promethazine Hydrochloride
Caffeine
Suppository
6427079ea643246ff35189db
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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Bayview Pharmacy's Dihydroergotamine Mesylate 5 mg/Promethazine HCl 50 mg/Caffeine 100 mg Suppository is a solid dosage form that is inserted into a body cavity, typically the rectum, where it dissolves or melts to release medication for local or systemic absorption.

Designed to provide fast-acting relief from headache pain and associated symptoms, such as nausea and sensitivity to light and sound, this formulation combines dihydroergotamine mesylate, promethazine HCl, and caffeine. These active ingredients work synergistically to reduce inflammation and constrict blood vessels, providing relief from headache pain.

The suppository formulation is easy to use and can be administered rectally. Patients should follow the instructions provided by their healthcare provider when using this formulation. It is important to note that this formulation should not be used more than twice a day and should not be used for more than 10 days in a row.

If you have any questions about Bayview Pharmacy's Dihydroergotamine Mesylate 5 mg/Promethazine HCl 50 mg/Caffeine 100 mg Suppository or any other headache treatment, please reach out to us. We are here to help you find the best treatment for your headache disorder.

Drug Interactions

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This compounded formulation of Dihydroergotamine Mesylate 5 mg, Promethazine HCl 50 mg, and Caffeine 100 mg in a suppository form is specifically designed for the treatment of various types of headaches including migraine, cluster headache, menstrual migraine, post-traumatic headache, and tension-type headache. It is a solid dosage form that is inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication for local or systemic absorption.

The formulation combines the therapeutic effects of dihydroergotamine mesylate, promethazine HCl, and caffeine. Dihydroergotamine mesylate is a vasoconstrictor that reduces inflammation and pain associated with migraines and cluster headaches. Promethazine HCl is an antihistamine that helps to alleviate nausea and vomiting often associated with these conditions. Caffeine, a stimulant, works to reduce the severity of headache pain.

However, this formulation is contraindicated in patients with a history of coronary artery disease, peripheral vascular disease, ischemic heart disease, uncontrolled hypertension, severe hepatic impairment, and in those who are pregnant or breastfeeding. It should also be used with caution in patients with a history of glaucoma, hypertension, or seizure disorders. Patients are advised to avoid alcohol and activities requiring alertness, such as driving or operating machinery, while taking this medication.

If you have any questions about this formulation or its use, please do not hesitate to reach out for further information.

How Does it Work

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This compounded formulation of Dihydroergotamine Mesylate 5 mg, Promethazine HCl 50 mg, and Caffeine 100 mg in a suppository form is designed to provide relief from various types of headaches including migraines, cluster headaches, menstrual migraines, post-traumatic headaches, and tension-type headaches. The combination of these three active ingredients works synergistically to alleviate symptoms by reducing inflammation, constricting blood vessels, and mitigating pain.

Dihydroergotamine Mesylate, an ergot alkaloid, functions to decrease inflammation and constrict blood vessels. Promethazine HCl, an antihistamine, aids in reducing inflammation and pain. Caffeine, a well-known stimulant, not only helps to lessen pain but also enhances alertness. This unique blend of ingredients is designed to lessen the severity and duration of headaches.

The suppository is to be inserted into the rectum and should remain in place for up to 30 minutes. It is crucial to adhere to the instructions provided by your healthcare provider when using this formulation. If you have any queries regarding the usage of this formulation, do not hesitate to seek advice from a healthcare professional.

Other Uses

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This compounded formulation of Dihydroergotamine Mesylate 5 mg, Promethazine HCl 50 mg, and Caffeine 100 mg is presented in a suppository form. It is designed to be inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication. This formulation is primarily used for the treatment of various types of headaches including migraines, cluster headaches, menstrual migraines, post-traumatic headaches, and tension headaches.

It is crucial to note that this formulation is contraindicated in patients with a history of coronary artery disease, peripheral vascular disease, or ischemic heart disease. It should also not be used in patients with uncontrolled hypertension, or in those who have had a stroke or transient ischemic attack. Patients should be advised to avoid activities requiring mental alertness or physical coordination until they understand how this formulation affects them. Additionally, alcohol should be avoided while taking this medication.

If you have any questions or concerns about the use of this formulation, please do not hesitate to contact us. It is always important to use this medication as directed by a healthcare professional and to discuss any potential side effects or interactions with other medications or substances.

Frequently Asked Questions

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What is the purpose of this compounded formulation of Dihydroergotamine Mesylate 5 mg/Promethazine HCl 50 mg/Caffeine 100 mg Suppository?

This formulation is designed to deliver a combination of medications for the treatment of conditions such as migraines, nausea, and fatigue. The suppository form allows for the medication to be absorbed either locally or systemically, depending on the intended treatment.

How is this suppository administered?

This suppository is typically inserted into a body cavity, most commonly the rectum or vagina. It then dissolves or melts to release the medication.

What are the active ingredients in this suppository?

The active ingredients in this suppository are Dihydroergotamine Mesylate, Promethazine HCl, and Caffeine.

What is the function of each active ingredient in this suppository?

Dihydroergotamine Mesylate is used to treat migraines, Promethazine HCl is used to treat nausea and vomiting, and Caffeine is used to increase the effectiveness of these medications.

What should I do if I miss a dose?

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

What are the potential side effects of this suppository?

Side effects may include dizziness, drowsiness, dry mouth, or constipation. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Can this suppository be used during pregnancy?

Consult your healthcare provider before using this medication during pregnancy. It should only be used when clearly needed and the potential benefits outweigh the potential risks.

Can I drink alcohol while using this suppository?

Alcohol may increase the risk of certain side effects, such as drowsiness and dizziness. It is recommended to limit or avoid alcohol while using this medication.

How should I store this suppository?

Store this medication at room temperature, away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

What should I do in case of an overdose?

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Dihydroergotamine Mesylate 5 mg/Promethazine HCl 50 mg/Caffeine 100 mg Suppository
Suppository
30 suppositories
controlled

Insert 1 unwrapped suppository

As needed