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Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension

Customized and compounded at Bayview Pharmacy, this Estriol/Estradiol sublingual suspension helps manage menopausal symptoms, hypoestrogenism, and osteoporosis.
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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Estriol
Estradiol
Suspension
6427079ea6432439e3518acb

Formula Information

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This compounded formulation of Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml is a sublingual suspension, a liquid dosage form where the active ingredients are uniformly dispersed throughout a liquid medium. This ensures a homogeneous mixture for administration, providing a consistent dose of medication with each use. The formulation contains a balanced combination of estriol and estradiol, two hormones naturally produced by the body, in a 50/50 ratio.

It is primarily used to manage a variety of conditions related to hormonal imbalances, such as menopausal symptoms, postmenopausal osteoporosis, and as part of hormone replacement therapy. During menopause, the body's production of these hormones decreases, leading to a range of symptoms. This formulation helps to replenish the body's hormone levels, providing relief from menopausal symptoms such as hot flashes, night sweats, mood changes, and vaginal dryness.

It aids in maintaining bone density, thereby reducing the risk of fractures, a common concern in postmenopausal women. As a hormone replacement therapy, it helps restore hormonal balance in the body, which can alleviate a range of symptoms and improve overall health.

The sublingual suspension is designed for easy administration. It is absorbed quickly into the bloodstream through the tissues under the tongue. This method of administration bypasses the digestive system, ensuring a higher bioavailability of the medication and faster onset of action.

As with any medication, it is crucial to use this formulation as directed by your healthcare provider. Dosage instructions should be followed carefully to ensure the medication's safety and effectiveness. If you have any questions or concerns about this formulation or its use in treating your specific condition, please consult with your healthcare provider or pharmacist.

Drug Interactions

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Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension is a compounded formulation designed for the treatment of various hormone-related conditions. This includes menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. It may also be used in the management of osteoporosis and endometriosis.

It's important to note that this medication may interact with other drugs, including anticoagulants, anti-seizure medications, and certain antibiotics. Interactions may also occur with specific herbal supplements, such as St. John's Wort. Therefore, it's crucial for patients to inform their healthcare provider of all medications and supplements they are currently taking before starting this treatment.

Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension is contraindicated in patients with a history of stroke, blood clots, or certain types of cancer. Furthermore, patients should be aware that this medication may increase the risk of breast cancer, endometrial cancer, and ovarian cancer. It's essential to discuss these risks with your healthcare provider to make an informed decision about your treatment options.

If you have any questions or concerns about Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension, please do not hesitate to reach out for further information.

How Does it Work

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Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension is a specially compounded medication designed to address a variety of health conditions. This formulation is administered sublingually, which means it is placed under the tongue and allowed to dissolve. The medication is available in a range of doses, from 0.25-1 mg/0.5-0.1 ml, and is composed of a 50/50 ratio of estriol and estradiol. These are hormones that are naturally produced by the body and play crucial roles in numerous bodily functions.

This formulation is primarily used to manage menopausal symptoms, postmenopausal osteoporosis, and as a part of hormone replacement therapy. Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension can alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. It can also help to reduce the risk of postmenopausal osteoporosis by increasing bone density. Furthermore, it can be used as a form of hormone replacement therapy to replenish hormones that are no longer being produced by the body.

When using Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension, it is crucial to adhere to the instructions provided by your healthcare provider. The medication should be taken as directed and should not be taken more or less than prescribed. It is also important to monitor your symptoms and report any changes to your healthcare provider. If you have any questions about this formulation or how it works, please consult with your healthcare provider or pharmacist.

Other Uses

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This compounded formulation of Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension is a versatile treatment option that may be used for a variety of conditions. It is primarily used in the management of endometriosis and premenstrual dysphoric disorder, but its benefits extend beyond these applications. It may also be utilized in the treatment of breast cancer, and in reducing the risk of developing certain types of cancer, such as ovarian cancer.

Furthermore, this formulation may be beneficial in reducing the risk of cardiovascular disease. It has also been associated with a decreased risk of developing dementia and Alzheimer's disease. In addition, it may be used to mitigate the risk of certain types of depression and urinary incontinence. Lastly, this formulation may be beneficial in reducing the risk of developing certain types of endometrial hyperplasia.

It is important to note that the use of this formulation should be under the guidance of a healthcare professional. If you have any questions about the use of this formulation for any of these conditions, please consult with your healthcare provider.

Frequently Asked Questions

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What is the Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension?

This is a compounded formulation of Estriol and Estradiol, two forms of estrogen, in a liquid dosage form. The ingredients are uniformly dispersed throughout a liquid medium, providing a homogeneous mixture for administration.

How is this medication administered?

This medication is administered sublingually, which means it is placed under the tongue and allowed to dissolve.

What does the 50%/50% ratio mean in this formulation?

The 50%/50% ratio indicates that the formulation contains equal parts of Estriol and Estradiol.

What does the 0.25-1 mg/0.5-0.1 ml dosage mean?

This refers to the concentration of the active ingredients in the suspension. It means that there is between 0.25 to 1 milligram of the active ingredients per 0.5 to 0.1 milliliter of the liquid suspension.

What is the purpose of this medication?

This medication is typically used in hormone replacement therapy for menopausal symptoms or other conditions where estrogen levels need to be supplemented or regulated.

What are the potential side effects of this medication?

As with any medication, side effects can occur. These may include headaches, breast tenderness, mood changes, and nausea. Always consult your healthcare provider for a complete list of potential side effects.

Can this medication be taken with other medications?

It's important to discuss all medications and supplements you are currently taking with your healthcare provider to avoid potential interactions.

How should this medication be stored?

This medication should be stored at room temperature, away from light and moisture. Always keep medications out of reach of children.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

What should I do in case of an overdose?

If an overdose is suspected, contact a poison control center or emergency room immediately.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Related Formulas

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Estriol/Estradiol [50%/50%] 0.25-1 mg/0.5-0.1 ml Sublingual Suspension
Suspension
30 mL
controlled

Take orally