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Estriol/Estradiol [80%-20%] 1.25 mg/ml - 5 mg/ml Topical Gelstriol/Estradiol [50%/50%] 0.5-1 mg/Progesterone 50-200 mg Troche

FDA-approved generic
Dose form
Troches
Active ingredients
Estriol
Estradiol
Progesterone

This compounded formulation features a blend of estriol/estradiol (80%-20%) at 1.25-5 mg/ml and estriol/estradiol (50%-50%) at 0.5-1 mg/ml, complemented by progesterone at 50-200 mg. It is typically used for the treatment of conditions such as vaginal atrophy, menopause, uterine fibroids, endometriosis, and polycystic ovary syndrome.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Estriol
Estradiol
Progesterone
Troches
6427079ea643247ebd518ac5
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This compounded formulation is a unique blend of estriol/estradiol [80%-20%] 1.25 mg/ml - 5 mg/ml in a topical gel form, and estriol/estradiol [50%/50%] 0.5-1 mg/progesterone 50-200 mg in a troche form. The troche is a square-shaped solid dosage form designed to dissolve slowly in the mouth, delivering medication through oral mucosa absorption for targeted local or systemic effects. This combination is specifically designed to treat a variety of disease states.

For menopausal symptoms such as hot flashes, night sweats, and vaginal dryness, the estriol/estradiol component of this formulation can provide significant relief.

It's important to note that the effectiveness of this formulation can vary depending on the individual's specific health needs and circumstances. Therefore, it's crucial to consult with a healthcare provider before starting any new medication regimen. If you have any questions about this formulation or how it can be used to treat these disease states, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the information and support you need.

Drug Interactions

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This compounded formulation of Estriol/Estradiol [80%-20%] 1.25 mg/ml - 5 mg/ml Topical Gel and Estriol/Estradiol [50%/50%] 0.5-1 mg/Progesterone 50-200 mg Troche is designed to address a range of health conditions, including menopausal symptoms, postmenopausal osteoporosis, and as part of hormone replacement therapy. The two key components, Estriol and Estradiol, are estrogen hormones that work in tandem to alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. Estriol, being a milder form of estrogen, and Estradiol, a more potent variant, provide a balanced approach to symptom management.

Progesterone, another hormone in this formulation, serves to counterbalance the effects of estrogen, thereby helping to reduce the risk of endometrial cancer. This formulation is also beneficial in the treatment of postmenopausal osteoporosis, as it aids in increasing bone density and reducing the risk of fractures. Furthermore, it is used in hormone replacement therapy to replenish the hormones that are lost during menopause.

It is crucial to be aware that this formulation may interact with other medications, including anticoagulants, anticonvulsants, and certain antibiotics. Additionally, it may increase the risk of certain side effects, such as nausea, vomiting, breast tenderness, and headaches. More serious risks include an increased likelihood of blood clots, stroke, and heart attack.

If you have any questions or concerns about this formulation or its potential interactions, it is recommended to consult with a healthcare professional for personalized advice.

How Does it Work

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This compounded formulation combines estriol/estradiol (80%-20%) 1.25 mg/ml - 5 mg/ml in a topical gel and estriol/estradiol (50%/50%) 0.5-1 mg/progesterone 50-200 mg in a troche. It is designed to address a range of conditions including menopausal symptoms, endometriosis, and uterine fibroids.

The estriol/estradiol topical gel is applied directly to the skin, typically once or twice daily. It delivers a consistent release of hormones into the bloodstream, helping to alleviate symptoms such as hot flashes, night sweats, and vaginal dryness.

The estriol/estradiol troche is a square-shaped solid dosage form designed to dissolve slowly in the mouth. It is typically taken once or twice daily and delivers medication through oral mucosa absorption for targeted local or systemic effects. This method of delivery helps to alleviate symptoms such as irregular menstrual cycles, heavy bleeding, and pelvic pain.

The progesterone troche, also a square-shaped solid dosage form, is designed to dissolve slowly in the mouth. It is typically taken once or twice daily and delivers medication through oral mucosa absorption for targeted local or systemic effects. This method of delivery helps to alleviate symptoms associated with endometriosis and uterine fibroids.

For any questions or further information about this formulation, please do not hesitate to reach out.

Other Uses

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This compounded formulation of Estriol/Estradiol [80%-20%] 1.25 mg/ml - 5 mg/ml Topical Gel and Estradiol/Estradiol [50%/50%] 0.5-1 mg/Progesterone 50-200 mg Troche is a versatile treatment option for a variety of conditions. It can be used to address hypoestrogenism, a condition characterized by low levels of estrogen in the body. This formulation can also be used in the treatment of breast cancer, a common type of cancer in women.

Furthermore, this formulation can be used to reduce the risk of endometrial hyperplasia in postmenopausal women who are taking conjugated estrogens. Endometrial hyperplasia is a condition that thickens the lining of the uterus and can lead to cancer. This formulation can also be used to manage symptoms of premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome that includes physical and behavioral symptoms.

Additionally, this formulation can be used to reduce the risk of endometrial cancer in women with an intact uterus who are taking conjugated estrogens. It can also be used to treat symptoms of vulvovaginal atrophy, such as vaginal dryness, itching, burning, and dyspareunia, which is painful sexual intercourse due to medical or psychological causes. If you have any questions about how this formulation can be used to treat other conditions, please consult with a healthcare professional.

Frequently Asked Questions

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What is the Estriol/Estradiol [80%-20%] 1.25 mg/ml - 5 mg/ml Topical Gel and Estriol/Estradiol [50%/50%] 0.5-1 mg/Progesterone 50-200 mg Troche?

This is a compounded formulation of hormones including Estriol, Estradiol, and Progesterone. The Estriol/Estradiol [80%-20%] 1.25 mg/ml - 5 mg/ml is a topical gel, while the Estriol/Estradiol [50%/50%] 0.5-1 mg/Progesterone 50-200 mg is a troche, a square-shaped solid dosage form designed to dissolve slowly in the mouth.

How does the troche work?

The troche is designed to dissolve slowly in the mouth, delivering medication through oral mucosa absorption. This allows for targeted local or systemic effects, depending on the medication and the patient's needs.

How should I use the topical gel?

The topical gel should be applied as directed by your healthcare provider. It is typically applied to the skin, where it is absorbed into the body.

What are the benefits of this compounded formulation?

This compounded formulation allows for personalized dosing and targeted delivery of medication. It can be particularly beneficial for patients who have specific needs that are not met by standard formulations.

Are there any side effects?

As with any medication, there can be side effects. These can vary depending on the individual and the specific formulation. It's important to discuss potential side effects with your healthcare provider.

Can anyone use this formulation?

This formulation is typically prescribed for specific health conditions and may not be suitable for everyone. Always consult with your healthcare provider before starting any new medication.

How should I store this medication?

Store this medication as directed by your healthcare provider or pharmacist. Typically, it should be kept in a cool, dry place out of reach of children.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take two doses at the same time.

Can I take this medication with other medications?

It's important to discuss all medications you're currently taking with your healthcare provider, as there can be interactions. Always consult with your healthcare provider before starting any new medication.

What should I do if I experience any adverse reactions?

If you experience any adverse reactions, contact your healthcare provider immediately. If the reaction is severe, seek emergency medical attention.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Estriol/Estradiol [80%-20%] 1.25 mg/ml - 5 mg/ml Topical Gelstriol/Estradiol [50%/50%] 0.5-1 mg/Progesterone 50-200 mg Troche
Troches
90 troches
controlled

Place 1 troche between cheek and gum and let slowly dissolve

Once daily