Our specially compounded Fluocinonide 0.05%/Ketoconazole 2%/Salicylic Acid 10% Topical Shampoo is a multi-functional medicated formulation designed to address a variety of dermatological conditions affecting the scalp. This liquid formulation is intended for use as a regular shampoo, with the added benefits of potent medicinal ingredients. It is suitable for patients who require a therapeutic approach to scalp treatment while maintaining the convenience of a cleansing hair care product.

Fluocinonide, a potent corticosteroid, is included at a concentration of 0.05% and is effective in reducing inflammation, itching, and swelling. It is commonly used to treat various forms of scalp psoriasis, eczema, and dermatitis. By incorporating fluocinonide into the shampoo, patients can directly target inflammatory scalp conditions during their routine hair washing.

Ketoconazole, present at 2%, is an antifungal agent that works by disrupting the cell membrane of fungi, leading to their death. It is particularly effective against the fungus Pityrosporum ovale, which plays a role in dandruff and seborrheic dermatitis. Ketoconazole's inclusion in the shampoo helps in the management of fungal-related scalp conditions, reducing flaking, scaling, and itching associated with these disorders.

Salicylic Acid is included at a 10% concentration, serving as a keratolytic agent. It helps to soften and remove the outer layer of the skin, which is beneficial for conditions with excessive scaling or buildup of dead skin cells, such as psoriasis. Salicylic Acid's exfoliating properties promote the shedding of dead skin from the scalp, thereby reducing scaling and improving the penetration of the other active ingredients.

This topical shampoo formulation is designed to be used two to three times a week, or as directed by a healthcare provider. It should be applied to wet hair, lathered, and left in place for several minutes to allow the active ingredients to work effectively before rinsing thoroughly. Patients should be advised to avoid contact with the eyes and other mucous membranes, and to use the product only as directed to minimize the risk of systemic absorption and potential side effects.

It is important for both patients and prescribers to be aware that while this compounded shampoo can be highly effective for the treatment of specific scalp conditions, it may not be suitable for everyone. Patients with known hypersensitivity to any of the ingredients, pregnant or breastfeeding women, or those with certain medical conditions should consult with their healthcare provider before use. Additionally, as with any topical corticosteroid, prolonged use of fluocinonide can lead to skin atrophy or other adverse effects, and therefore, treatment should be monitored by a healthcare professional.

For any questions or concerns regarding this formulation, or to discuss individual patient needs, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing personalized care and is ready to assist with any inquiries to ensure the safe and effective use of this medicated shampoo.

The formulation combines fluocinonide, a potent corticosteroid, with ketoconazole, an antifungal agent, and salicylic acid, a keratolytic. This combination is designed to treat various scalp conditions, such as psoriasis, seborrheic dermatitis, and fungal infections. While the formulation is intended for topical use on the scalp, it is important to consider potential interactions with other medications and substances.

Fluocinonide, being a corticosteroid, can interact with other topical medications that affect the hypothalamic-pituitary-adrenal (HPA) axis. Caution should be exercised when using other corticosteroids or medications that can alter corticosteroid metabolism. Systemic absorption, although minimal with topical application, can be increased with occlusive dressings or extensive body surface treatment, potentially leading to systemic corticosteroid effects.

Ketoconazole, as an antifungal, can inhibit cytochrome P450 enzymes, particularly CYP3A4. While systemic absorption is low with topical application, there is still a potential for interaction with systemic medications metabolized by CYP3A4. Patients should be advised to inform their healthcare provider of all systemic medications they are taking, including over-the-counter drugs and herbal supplements, to assess any potential interactions.

Salicylic acid can enhance the absorption of other topically applied medications due to its keratolytic properties, which increase skin permeability. It should be used with caution in combination with other topical agents, especially those known to be irritating or sensitizing. Additionally, salicylic acid should be used with caution in patients with renal dysfunction, as systemic absorption, although generally low, can lead to salicylate toxicity in patients with compromised renal function.

Patients should be advised to avoid concurrent use of other topical products that can cause irritation, dryness, or have exfoliating effects unless directed by a healthcare provider. The use of this formulation under occlusion, such as with a shower cap, should be done only under medical supervision, as this can increase systemic absorption of the active ingredients. Patients should also be aware that alcohol consumption may enhance the systemic absorption of salicylic acid, and excessive use of alcohol should be avoided.

It is important for patients to inform their healthcare providers of their complete medical history, including all medications they are currently using, before starting treatment with this formulation. If any signs of hypersensitivity or adverse reactions occur, use of the product should be discontinued immediately, and medical advice should be sought. For any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

The Fluocinonide 0.05%/Ketoconazole 2%/Salicylic Acid 10% Topical Shampoo is a medicated formulation designed to treat a variety of scalp conditions. This unique combination of active ingredients works synergistically to reduce inflammation, fight fungal infections, and exfoliate the scalp. Fluocinonide is a potent corticosteroid that helps to alleviate itching, redness, and swelling associated with inflammatory skin conditions such as psoriasis and eczema. By suppressing the immune response and inflammation, fluocinonide can provide significant relief from the symptoms of these disorders.

Ketoconazole, on the other hand, is an antifungal agent that targets the cell membrane of fungi, causing cell death and effectively treating infections such as seborrheic dermatitis and dandruff. It works by disrupting the synthesis of ergosterol, a key component of fungal cell membranes, which leads to increased membrane permeability and ultimately the death of the fungal cell. This action not only treats the existing infection but also helps prevent recurrence when used regularly.

Salicylic Acid is a keratolytic, which means it helps to soften and remove the outer layer of the skin. In this formulation, it serves to exfoliate the scalp, clearing away dead skin cells and reducing the buildup of scales associated with psoriasis. By promoting the shedding of the outer skin, salicylic acid can enhance the penetration of fluocinonide and ketoconazole, making them more effective. Additionally, it helps to unclog hair follicles, which can reduce dandruff and improve the overall health of the scalp.

When used as directed, this topical shampoo provides a comprehensive treatment approach for patients suffering from scalp psoriasis, seborrheic dermatitis, and other related conditions. The liquid formulation is designed for ease of application during regular showering or bathing routines. It lathers well to cleanse the hair and scalp, removing oils and impurities, while the active ingredients work to treat the underlying condition. Patients should follow the specific instructions provided by their healthcare provider or pharmacist regarding the frequency and duration of use to achieve the best results.

For prescribers, it is important to note that this formulation should be used with caution in patients with a known hypersensitivity to any of the ingredients. Additionally, the use of topical corticosteroids, such as fluocinonide, may carry the risk of systemic absorption, particularly with prolonged use or over large surface areas, which could lead to systemic side effects. Therefore, it is essential to monitor patients for any adverse reactions and adjust treatment as necessary.

If you have any questions or require further information about this formulation and its use in treating specific disease states, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the support and guidance needed to ensure the safe and effective use of this medicated shampoo.

The Fluocinonide 0.05%/Ketoconazole 2%/Salicylic Acid 10% Topical Shampoo is a multi-component medicated formulation primarily indicated for a variety of dermatological conditions affecting the scalp. Beyond its indicated uses for treating inflammatory, fungal, and proliferative disorders such as psoriasis, seborrhoeic dermatitis, and tinea capitis, this shampoo may serve additional therapeutic roles. For instance, the anti-inflammatory properties of fluocinonide can be beneficial in alleviating the symptoms of other itchy and inflammatory scalp conditions that are not strictly categorized under common disease states, provided the condition is responsive to corticosteroids.

Ketoconazole, an antifungal component, may be useful beyond the treatment of fungal infections. Due to its mechanism of action, which involves disrupting the cell membrane of fungi, ketoconazole may also aid in managing conditions like folliculitis, where there is inflammation of hair follicles sometimes associated with fungal involvement. Furthermore, this ingredient has been found to have some efficacy in reducing hair loss in individuals with androgenetic alopecia when used intermittently, although it's not primarily prescribed for this purpose.

Salicylic acid, known for its keratolytic properties, can help in disorders characterized by aberrant keratinization. Its use is not limited to psoriasis or seborrheic dermatitis as it may aid in the treatment of scalp conditions where excessive scaling or buildup of dead skin cells occurs. Moreover, salicylic acid can help in the management of common warts and acne at different sites, though its use in a shampoo formulation is particularly suited for scalp afflictions.

While the synergy of these ingredients in one formulation provides a broad-spectrum approach to scalp health, Bayview Pharmacy can tailor its use to individual needs based on prescriber guidance and patient-specific conditions. It's crucial for prescribers to consider the pharmacologic profiles of the active ingredients when contemplating off-label uses and for patients to adhere to their healthcare provider’s directions to avoid potential adverse effects. Patients with a sensitivity to any ingredients, pregnant or lactating women, and individuals with certain medical conditions may require special consideration.

This formulation also exhibits secondary benefits such as the removal of scales, which can improve the efficacy of other topical treatments by enhancing their absorption. It is important to apply the shampoo as directed and to avoid contact with the eyes or mucous membranes. Should you experience irritation or an unusual reaction to the product, it is advised to discontinue use and consult your healthcare provider. For any further questions or guidance on the possible uses of this topical shampoo formulation, please do not hesitate to reach out to us at Bayview Pharmacy. We are here to provide comprehensive information and support to both patients and prescribers aiming to utilize this formulation effectively.