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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Prepared to a prescriber's order for one patient. Not FDA-approved.
This is a compounded suppository containing glutathione, prepared to a prescriber's order for one patient. Compounded preparations are not FDA-approved.
These listings cover every salt or ester form of each drug in the FDA National Drug Code Directory.
No FDA-approved (NDA or ANDA) product containing glutathione is listed. Products containing it are filed in the directory as homeopathic products and over-the-counter monograph drugs, in liquid, pellet, spray and soap forms. None of the listed products containing glutathione is in suppository form.
Suppository bases differ, and the base used decides how USP <795> classifies the preparation for beyond-use dating. The date printed on the label is the one to follow.
Glutathione is a naturally occurring antioxidant tripeptide that compounding pharmacies prepare by prescription as sterile injections, oral forms and topical preparations.
Glutathione is a small peptide built from three amino acids: glutamate, cysteine and glycine. Cells make it themselves and use it as a primary antioxidant, cycling between a reduced form (GSH) and an oxidized form (GSSG) to neutralize reactive oxygen species. Its sulfur group also binds copper at the active site of tyrosinase, the enzyme that drives melanin production, which is the proposed basis for its study as a skin lightening agent. No FDA-approved drug contains glutathione as an active ingredient for oral, injectable, nasal or topical use; the only approved product that includes a glutathione form is an intraocular irrigating solution used during eye surgery, which contains oxidized glutathione. Oral glutathione is sold as a dietary supplement with GRAS status for food use. Because nothing is manufactured as a drug for these routes, any prescription glutathione, whether injectable, oral, nasal or topical, is compounded. Compounded preparations are not FDA-approved and require a prescription.
Because no manufactured glutathione drug exists for these routes, there is no FDA label for them and no boxed warning. FDA has warned about compounded intravenous glutathione twice, in 2019 and 2026, after patients developed fever, chills, body aches, nausea, vomiting, low blood pressure and sepsis-like symptoms within minutes to hours of an infusion, some requiring hospital care; FDA attributed these to excessive endotoxin in dietary supplement grade powder that was not suitable for injection. Reported side effects of oral glutathione include gas, loose stools, flushing and weight gain; nebulized glutathione has caused cough and airway tightening in people with asthma, and reversible severe liver injury has been reported with intravenous use. Glutathione may interact with chemotherapy, and its use in people with cancer is theoretically contraindicated. Safety in pregnancy and breastfeeding has not been established, and no LactMed entry was found. If you notice side effects, talk to your prescriber or pharmacist.
Glutathione (gamma-glutamyl-cysteinyl-glycine) is the predominant intracellular thiol and maintains redox balance; proposed pigment effects include copper chelation at tyrosinase, interference with tyrosinase transport to premelanosomes, ROS quenching and a shift from eumelanin to pheomelanin synthesis (Sonthalia et al., 2016). Oral bioavailability data conflict: hepatic gamma-glutamyl transferase hydrolyzes the peptide, some single-dose studies show no plasma rise, longer trials show inconsistent increases, and neither cited source reports a clearance route or half-life. There is no labeled indication for any route a compounding pharmacy would prepare. In June 2022 FDA proposed that glutathione not be added to the 503A bulks list; the Pharmacy Compounding Advisory Committee voted 8 to 5, with one abstention, to recommend inclusion, a non-binding vote, and the minutes record no final decision. Prescribers have ordered compounded glutathione for skin lightening (Sonthalia et al., 2016), and it has been studied in Parkinson disease, cystic fibrosis and HIV with inconsistent results (Drugs.com monograph); the IJDVL review advises against intravenous use for skin lightening. Dosing and route are per prescriber. Sterile preparations require API manufactured for injectable use with endotoxin limits set from the maximum intended dose. Monitor liver function with repeated intravenous use. Glutathione is not a controlled substance.
Wash your hands. If the suppository is soft, chill it in its wrapper in the refrigerator or under cool water for a few minutes, then unwrap it. For rectal use, coat the tip with a water-soluble lubricant (not petroleum jelly), lie on your side with your upper knee bent, and insert it pointed end first past the muscle at the opening. For vaginal use, lie on your back with knees bent and insert it as far as it comfortably goes, by finger or applicator; bedtime use limits leakage, and a panty liner protects clothing. Stay lying down about 15 minutes. Wash your hands.
Suppositories are nonaqueous, so under USP <795> they can carry a beyond-use date of up to 180 days at controlled room temperature or in the refrigerator when no other stability data apply. Storage depends on the base: fatty bases can soften at room temperature and may be labeled for the refrigerator, while polyethylene glycol bases usually do not need refrigeration. Keep them cool so they do not melt, and refrigerate them if your label says to.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert 1 unwrapped suppository
