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The Hydrocortisone Acetate 50 mg Vaginal Suppository is a solid dosage form designed for insertion into the vaginal cavity. Upon insertion, the suppository dissolves or melts, facilitating the release of hydrocortisone acetate for local absorption. This formulation is specifically compounded to treat inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in the vaginal area. It may also be used to address certain gynecological conditions characterized by inflammation and itching that can benefit from topical corticosteroid therapy.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Hydrocortisone Acetate 50 mg Vaginal Suppositories are a specialized solid dosage form designed for insertion into the vaginal cavity. Upon insertion, the suppository base, typically composed of a substance like cocoa butter or a glycerinated gelatin, dissolves or melts at body temperature, allowing the active medication, Hydrocortisone Acetate, to be released and absorbed locally within the vaginal tissue.
Hydrocortisone Acetate is a corticosteroid, which acts by reducing inflammation, itching, and swelling. When formulated into a 50 mg vaginal suppository, it is primarily used for its anti-inflammatory and immunosuppressive effects on the vaginal mucosa. This can be beneficial in treating various disease states such as inflammatory lesions of the vagina, atrophic vaginitis, and certain cases of vaginal irritation and itching. By acting directly at the site of inflammation, Hydrocortisone Acetate can provide relief from symptoms and promote healing of the affected tissues.
For patients, it is important to understand that while Hydrocortisone Acetate vaginal suppositories can provide significant relief from discomfort, they should be used as directed by a healthcare provider. The suppositories should be stored in a cool place to prevent melting and should be inserted as instructed, typically lying down to ensure the suppository remains in place to dissolve properly. Patients should be aware of potential side effects, which may include local irritation, burning, or itching. Long-term use of corticosteroids can lead to additional effects, and therefore, treatment duration should be limited to the shortest possible time to manage symptoms.
Prescribers should consider this formulation for patients who require localized anti-inflammatory treatment within the vaginal area. It is crucial to assess the patient's overall health, current medications, and medical history to avoid potential drug interactions and contraindications. Monitoring for systemic absorption and potential adrenal suppression is also recommended with prolonged use. The choice of a 50 mg dose allows for significant therapeutic effect while minimizing the risk of systemic side effects when used appropriately.
Bayview Pharmacy's team of compounding pharmacists is dedicated to providing high-quality, customized medications to meet the unique needs of each patient. We are available to answer any questions and provide additional information to ensure the safe and appropriate use of Hydrocortisone Acetate 50 mg Vaginal Suppositories. If you have any questions or require further assistance, please do not hesitate to reach out to us.
Hydrocortisone acetate is a corticosteroid used for its anti-inflammatory and immunosuppressive properties. When formulated as a 50 mg vaginal suppository, it is intended for local administration to treat inflammatory conditions of the vagina or rectum. It is important to consider potential drug interactions when using hydrocortisone acetate in this dosage form.
One key interaction is with other corticosteroids, whether administered orally, topically, or by injection. Concurrent use may increase the systemic effects of corticosteroids, potentially leading to Cushing's syndrome or adrenal suppression. Patients should inform their healthcare provider if they are taking any other form of corticosteroid.
Enzyme inducers, such as phenytoin, phenobarbital, ephedrine, and rifampin, may decrease the plasma concentration of hydrocortisone, reducing its efficacy. Conversely, enzyme inhibitors like ketoconazole can increase plasma levels of hydrocortisone, potentially leading to increased risk of systemic side effects.
Hydrocortisone may also interact with anticoagulants like warfarin. Corticosteroids can alter the response to anticoagulants, and patients may require closer monitoring of their coagulation status and possible adjustment of their anticoagulant dosage.
Nonsteroidal anti-inflammatory drugs (NSAIDs) taken concurrently with hydrocortisone may increase the risk of gastrointestinal ulceration or bleeding. Patients should be monitored for signs of gastrointestinal distress and be advised to report any severe abdominal pain or signs of bleeding.
Diabetic patients should be aware that corticosteroids can increase blood glucose levels. Those using hydrocortisone acetate suppositories may require more frequent monitoring of their blood glucose and adjustments to their diabetes medication.
Immunosuppressive effects of hydrocortisone could be compounded when used with other immunosuppressants, raising the risk of infection. Patients should be counseled on the signs of infection and advised to seek medical attention promptly if they suspect an infection.
Lastly, live or live-attenuated vaccines should be used with caution in patients receiving corticosteroids due to the potential for decreased antibody response and increased risk of adverse reactions from the vaccine.
It is essential for patients and prescribers to be aware of these potential interactions when considering the use of hydrocortisone acetate vaginal suppositories. This is not an exhaustive list, and other interactions may exist. For personalized advice and to ensure safe use of this medication, patients should consult with their healthcare provider or pharmacist. If you have any questions or require further information, please reach out to us at Bayview Pharmacy.
The Hydrocortisone Acetate 50 mg Vaginal Suppository is a solid dosage form designed to be inserted into the vagina, where it dissolves or melts at body temperature. Upon insertion, the suppository base, typically made from a substance like cocoa butter or a synthetic substitute, begins to melt due to the warmth of the human body, allowing the active ingredient, hydrocortisone acetate, to be released.
Hydrocortisone acetate is a corticosteroid, which means it is a synthetic version of the hormones produced by the adrenal glands. It works by reducing inflammation, itching, and swelling. When applied locally to the vagina, hydrocortisone acetate acts on the cells in the mucosal lining to inhibit the release of substances in the body that cause inflammation. This can help to alleviate symptoms associated with inflammatory conditions of the vagina or vulva, such as itching, redness, and swelling.
This formulation is particularly useful for treating localized conditions where systemic corticosteroid treatment is not necessary or desired. By using a suppository, the medication can exert its effects directly at the site of inflammation with minimal systemic absorption, reducing the potential for systemic side effects that can occur with oral or parenteral corticosteroid administration.
Hydrocortisone acetate vaginal suppositories may be used in the management of inflammatory conditions of the vagina and vulva, such as atrophic vaginitis, lichen sclerosus, or other non-infectious inflammations. It is important to note that this medication should only be used under the guidance of a healthcare provider, as incorrect use or overuse of corticosteroids can lead to complications. Additionally, this medication is not suitable for treating vaginal infections, as it does not have antimicrobial properties.
Patients should be instructed on how to properly insert the suppository to ensure that the medication is delivered effectively. It is usually recommended to insert the suppository before bedtime to reduce the likelihood of the suppository being expelled and to allow for prolonged contact with the affected area during sleep.
For prescribers, it is important to consider the patient's overall medical condition and the presence of any contraindications to corticosteroid use, such as active infections. The duration of treatment should be limited to the shortest period necessary to achieve symptom relief, and patients should be monitored for any signs of systemic corticosteroid effects or local reactions.
If you have any questions about the Hydrocortisone Acetate 50 mg Vaginal Suppository or its use in treating specific disease states, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure appropriate treatment for your patients.
Hydrocortisone Acetate 50 mg Vaginal Suppository is used for treating inflammatory conditions of the vagina, such as certain types of vaginitis. It may also be used to reduce swelling, itching, and discomfort associated with certain gynecological conditions or procedures.
To use the suppository, you should insert it into the vagina, typically lying down on your back with your knees bent, pushing it in gently until it cannot be felt anymore. It should be done ideally at bedtime to ensure the medication stays in place and works overnight. Always follow the specific instructions provided by your healthcare provider.
The frequency of usage will depend on the instructions given by your healthcare provider, as it can vary based on the condition being treated and its severity. It's important not to use it more often than prescribed.
It's best to consult with your healthcare provider regarding the use of Hydrocortisone Acetate Vaginal Suppositories during menstruation, as it can affect the absorption and effectiveness of the medication.
Possible side effects can include local irritation, burning sensation, itching, or an increase in vaginal discharge. Systemic side effects are uncommon due to local use, but prolonged or excessive use can lead to systemic effects like suppression of adrenal gland function. Contact your healthcare provider if you experience any severe or persistent side effects.
It's recommended to avoid sexual intercourse while using Hydrocortisone Acetate Vaginal Suppositories. The medication can affect the integrity of condoms and diaphragms, and intercourse can also interfere with the healing process.
Suppositories should be stored in a cool place, typically at room temperature, away from light and moisture. Do not store in the bathroom and keep them away from children and pets. Do not freeze the suppositories unless instructed to do so by your pharmacist or the product labeling.
If you miss a dose, insert the missed suppository as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double up to make up for a missed dose.
Though rare, an allergic reaction to Hydrocortisone Acetate is possible. Seek immediate medical attention if you experience symptoms like rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
There are typically no dietary restrictions while using Hydrocortisone Acetate Vaginal Suppositories, but it's always important to follow any instructions provided by your healthcare provider regarding diet or any lifestyle guidelines to support treatment.
Consult with your healthcare provider before using Hydrocortisone Acetate Vaginal Suppositories during pregnancy. They will evaluate the potential benefits and risks before making a recommendation based on your specific condition.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert 1 unwrapped suppository
