Check out our most popular compounded medications! Get Started
The Isosorbide Dinitrate 5mg/ml Oral Suspension is a liquid dosage form that ensures the active ingredient, isosorbide dinitrate, is uniformly dispersed throughout the liquid medium. This homogeneous mixture allows for accurate dosing and ease of administration for patients. Isosorbide dinitrate is a nitrate that is commonly used to prevent chest pain (angina) in patients with certain heart conditions. This formulation is specifically designed to treat and manage symptoms associated with angina pectoris, heart failure, and to help improve exercise tolerance in individuals with these disease states.
```
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Isosorbide Dinitrate (ISDN) 5mg/ml Oral Suspension is a liquid medication specifically compounded to aid in the management of certain heart conditions. This formulation is designed to deliver a precise dose of ISDN, a nitrate that works by relaxing and widening blood vessels, making it easier for the heart to pump blood. The 5mg/ml concentration ensures that each milliliter of the suspension contains 5 milligrams of the active ingredient, allowing for accurate dosing tailored to the patient's needs.
The oral suspension form is particularly beneficial for patients who may have difficulty swallowing tablets or capsules, ensuring they receive their medication in a manageable and palatable liquid form. The uniform dispersion of ISDN throughout the liquid medium ensures consistency in dosing, as each milliliter of the suspension will contain the same amount of medication.
ISDN is commonly used in the treatment of angina pectoris (chest pain) associated with coronary artery disease. It helps to prevent angina attacks by decreasing the oxygen demand of the heart during episodes of increased workload. It is also used in the management of heart failure and esophageal spasms. By dilating the blood vessels, ISDN reduces the strain on the heart and improves blood and oxygen supply to the cardiac muscle.
Patients and prescribers should be aware that this medication should be used as directed, and it is important to shake the bottle well before each use to ensure the medication is properly mixed. Patients should also be counseled on potential side effects, which may include headaches, dizziness, or lightheadedness, due to the vasodilatory effects of the drug. It is crucial to monitor blood pressure regularly, as ISDN can cause hypotension. Additionally, tolerance to nitrates can develop, so treatment regimens may include a nitrate-free interval to prevent this.
For prescribers considering this formulation for their patients, it is important to assess the patient's medical history, current medications, and potential drug interactions. As compounding pharmacists at Bayview Pharmacy, we are equipped to customize this formulation to meet the unique needs of each patient and are available to answer any questions or concerns regarding this medication. If you have any questions or require further information about Isosorbide Dinitrate 5mg/ml Oral Suspension, please do not hesitate to reach out to us.
Isosorbide dinitrate is a nitrate that works by relaxing and widening blood vessels, making it easier for blood to flow through them and easier for the heart to pump. It is commonly used to prevent chest pain (angina) in patients with certain heart conditions. When considering the use of isosorbide dinitrate 5mg/ml oral suspension, it is important to be aware of potential drug interactions that may affect the efficacy of the medication or increase the risk of adverse effects.
One significant interaction is with phosphodiesterase inhibitors (PDE-5 inhibitors), such as sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra). These medications are used to treat erectile dysfunction and pulmonary hypertension. Concurrent use with isosorbide dinitrate can lead to severe hypotension (low blood pressure), syncope (fainting), or myocardial infarction (heart attack). Patients should not take PDE-5 inhibitors within 24 hours of taking isosorbide dinitrate.
Antihypertensive medications, including beta-blockers, calcium channel blockers, ACE inhibitors, and diuretics, may have additive effects when used with isosorbide dinitrate, leading to hypotension. Blood pressure should be monitored closely, and dosage adjustments may be necessary to avoid symptomatic hypotension.
Alcohol may also enhance the vasodilating and hypotensive effects of isosorbide dinitrate. Patients should be advised to limit alcoholic beverages while taking this medication. Additionally, the concurrent use of other vasodilators or drugs that decrease preload or afterload can enhance the hypotensive effects and should be used with caution.
Riociguat, a soluble guanylate cyclase stimulator, should not be used in combination with isosorbide dinitrate as it can significantly lower blood pressure and is contraindicated. Patients should inform their healthcare provider of all medications they are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.
Patients with certain medical conditions, such as severe anemia, closed-angle glaucoma, or head trauma, may require special consideration when using isosorbide dinitrate due to the potential for exacerbating these conditions. Additionally, caution is advised in patients with hypothyroidism, malnutrition, or hypothermia.
It is essential for patients and prescribers to communicate effectively about all aspects of treatment with isosorbide dinitrate oral suspension. If you have any questions or concerns regarding drug interactions or the management of specific disease states with this formulation, please reach out to us at Bayview Pharmacy for further assistance and personalized advice.
Isosorbide dinitrate (ISDN) is an organic nitrate compound that is widely used in the management of angina pectoris, a symptom of ischemic heart disease. The 5mg/ml oral suspension formulation of ISDN provides a liquid dosage form in which the active ingredient is uniformly dispersed throughout a liquid medium, ensuring a consistent and accurate dose with each administration. This homogeneity is particularly important for patients who may have difficulty swallowing tablets or capsules, or for those who require precise dosage adjustments.
The mechanism of action of ISDN involves the relaxation of vascular smooth muscle, which leads to vasodilation, primarily of the veins but also of the arteries to a lesser extent. This vasodilation reduces the preload and afterload on the heart, which decreases myocardial oxygen demand. In the case of angina, this reduction in oxygen demand helps to alleviate the chest pain associated with insufficient oxygenation of the heart muscle due to narrowed coronary arteries. Additionally, ISDN can improve blood flow to areas of the heart with poor circulation, further aiding in the relief of anginal symptoms.
ISDN is also used in the management of heart failure and esophageal spasms due to its vasodilatory effects. In heart failure, the reduction in preload and afterload can help to improve cardiac output and reduce symptoms. For esophageal spasms, the relaxation of smooth muscle can alleviate the pain associated with this condition.
It is important for patients and prescribers to understand that the onset of action for the oral suspension form of ISDN may be slightly delayed compared to sublingual or immediate-release oral dosage forms. However, the oral suspension provides a convenient and easily titratable option for those requiring long-term nitrate therapy. Patients should be counseled on the proper administration of the suspension, including shaking the bottle well before each dose to ensure the medication is evenly distributed.
As with all medications, there are potential side effects associated with ISDN, including headaches, dizziness, and hypotension. Tolerance to nitrates can also develop, so a nitrate-free interval is often recommended to maintain the drug's effectiveness. Prescribers should carefully consider the patient's overall medication regimen to avoid interactions, particularly with phosphodiesterase inhibitors, which can lead to severe hypotension when used concurrently with nitrates.
If you have any questions or require further information about the Isosorbide Dinitrate 5mg/ml Oral Suspension, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing the highest level of care and is available to assist with any inquiries regarding this formulation.
Isosorbide dinitrate (ISDN) is primarily known for its use in the management of angina pectoris due to coronary artery disease. However, beyond its conventional use for angina, isosorbide dinitrate in an oral suspension form may have other clinical applications. For example, it has been investigated for its utility in the management of heart failure, given its vasodilatory properties that can help to alleviate symptoms associated with this condition by improving cardiac output and reducing pulmonary congestion.
Additionally, isosorbide dinitrate has been considered in certain cases for the treatment of anal fissures due to its ability to cause smooth muscle relaxation, possibly providing symptomatic relief through the reduction of sphincter spasm and promotion of healing. Furthermore, there is some research suggesting that the vasodilatory effects of ISDN could be beneficial in managing conditions related to insufficient blood flow, such as peripheral vascular disease or possibly in the prevention of migraines in select patients, although these applications are less established and require further clinical evidence to confirm their efficacy.
Patients and prescribers should be aware that the use of isosorbide dinitrate for indications other than its approved use in angina should only occur under the guidance and monitoring of a healthcare professional. It is also important to understand that response to therapy can vary based on individual patient characteristics, and the prescriber should consider the risks and benefits on a case-by-case basis. If there are questions about the potential other uses of isosorbide dinitrate 5mg/ml oral suspension, or if individualized dose adjustments are required, please reach out to us at Bayview Pharmacy. Our team is available to provide professional advice and support to ensure optimal therapeutic outcomes for patients with a variety of conditions that may benefit from this medication.
Isosorbide Dinitrate Oral Suspension is a medication used for the prevention and treatment of chest pain associated with angina pectoris. By relaxing blood vessels, it helps improve blood flow and oxygen delivery to the heart muscle.
This medication should be stored at room temperature, away from light and moisture. Do not freeze the suspension or store it in the bathroom, and keep it out of reach of children and pets.
The suspension should be taken by mouth, as directed by your doctor. The dosage is based on your medical condition and response to treatment. Shake the bottle well before each use to ensure the medication is properly mixed.
Isosorbide Dinitrate Oral Suspension can be taken with or without food. However, you should try to take it the same way (with food or on an empty stomach) each time to ensure consistent effects.
Common side effects include headache, dizziness, lightheadedness, or flushing. If these effects worsen or persist, notify your doctor. It's important to sit or lie down at the first sign of any of these effects, and rise slowly from a sitting or lying position to reduce the risk of dizziness and lightheadedness.
Alcohol may increase certain side effects of Isosorbide Dinitrate Oral Suspension, such as dizziness and lightheadedness. It is advisable to limit or avoid alcoholic beverages while using this medication.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Avoid taking PDE5 inhibitors, such as sildenafil, tadalafil, or vardenafil, while on this medication, as it may lead to severe low blood pressure. Also avoid consuming products that contain high amounts of potassium, like salt substitutes, unless directed by your doctor.
Use this medication as part of your complete treatment plan, including lifestyle changes and other medications as directed by your healthcare provider. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call emergency services immediately. Symptoms of overdose may include a severe throbbing headache, fever, confusion, severe dizziness, fainting, and unusually fast or slow heartbeat.
Before using this medication, tell your healthcare provider about any allergies, medical history, especially of low blood pressure, other heart conditions such as a recent heart attack, or head injury. Also discuss all the products you use, including prescription drugs, nonprescription drugs, and herbal products.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Take orally
