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Formulas

Ketamine HCl 5%/Gabapentin 10%/Clonidine HCl 0.2%/Baclofen 2% Topical Gel

Bayview Pharmacy's compounded formulation of Ketamine HCl 5%/Gabapentin 10%/Clonidine HCl 0.2%/Baclofen 2% Topical Gel is a semisolid medication dispensed through a pump mechanism. This allows for easy and precise application on the skin, facilitating targeted treatment or absorption of active ingredients. It is used to treat conditions such as Neuropathic Pain, Fibromyalgia, Spasticity, Migraine, and Trigeminal Neuralgia.

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Topical Gel
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Formula Information

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Bayview Pharmacy is pleased to present a specialized topical gel formulation that combines Ketamine HCl 5%, Gabapentin 10%, Clonidine HCl 0.2%, and Baclofen 2%. This unique compounded formulation is designed to provide targeted relief for a range of conditions, including chronic pain, neuropathic pain, and spasticity.

Ketamine HCl, a long-established anesthetic, works by blocking the transmission of pain signals to the brain, providing effective pain relief. Gabapentin, an anticonvulsant, is commonly used in the treatment of neuropathic pain and seizures. Clonidine HCl, an antihypertensive, is utilized in the management of spasticity and hypertension. Baclofen, a muscle relaxant, is also used in the treatment of spasticity.

This unique combination of medications in a gel formulation has demonstrated effectiveness in providing relief from chronic pain, neuropathic pain, and spasticity. The semisolid formulation is dispensed through a pump mechanism, facilitating easy and precise application on the skin. This allows for the active ingredients to be absorbed directly into the skin, providing a more targeted and localized effect.

If you have any questions about this compounded formulation or how it can be used to manage your condition, please do not hesitate to contact us at Bayview Pharmacy. Our team is committed to helping you find the most suitable treatment option for your needs.

Drug Interactions

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This compounded formulation of Ketamine HCl 5%/Gabapentin 10%/Clonidine HCl 0.2%/Baclofen 2% is a semisolid topical gel designed for easy and precise application on the skin. It is primarily used for targeted treatment of chronic pain, neuropathic pain, and spasticity. Each of the active ingredients in this formulation plays a crucial role in managing these conditions.

Ketamine HCl, an NMDA receptor antagonist, has been widely used in the treatment of chronic and neuropathic pain. Gabapentin, an anticonvulsant, is known for its effectiveness in treating neuropathic pain and spasticity. Clonidine HCl, an alpha-2 agonist, has been used in the management of chronic pain and spasticity. Lastly, Baclofen, a GABA agonist, is commonly used to treat spasticity.

The combination of these medications in this topical gel formulation may provide synergistic effects in the treatment of chronic pain, neuropathic pain, and spasticity. However, it is crucial to review the patient's medication list prior to initiating therapy due to the potential for drug interactions. Monitoring for signs and symptoms of adverse reactions, such as sedation, dizziness, and hypotension, is also important.

It should be noted that this topical gel formulation is contraindicated in patients with a known hypersensitivity to any of the components of the formulation. It should also not be used in patients with a history of glaucoma, urinary retention, or severe cardiovascular disease. If you have any questions about this topical gel formulation or its use in the treatment of chronic pain, neuropathic pain, and spasticity, please do not hesitate to reach out.

How Does it Work

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Ketamine HCl 5%/Gabapentin 10%/Clonidine HCl 0.2%/Baclofen 2% Topical Gel is a specially compounded formulation designed to provide targeted relief from a range of conditions such as chronic pain, neuropathic pain, and spasticity. This unique blend of active ingredients is delivered in a semisolid gel form, which is easily dispensed through a pump mechanism for precise application on the skin.

The gel is absorbed through the skin, directly delivering the active ingredients to the affected area. Each ingredient plays a crucial role in managing pain and discomfort. Ketamine HCl, an anesthetic, works by blocking pain signals from reaching the brain, while also providing anti-inflammatory and anti-anxiety effects. Gabapentin, an anticonvulsant, aids in pain management by blocking nerve signals that cause pain.

Clonidine HCl, an antihypertensive medication, contributes to pain and spasticity reduction by decreasing the activity of the sympathetic nervous system. Baclofen, a muscle relaxant, further aids in managing spasticity by blocking nerve signals that cause muscle spasms. Together, these ingredients work synergistically to provide relief from chronic pain, neuropathic pain, and spasticity.

It is essential to use this medication as directed by your healthcare provider. The gel should be applied directly to the affected area and allowed to be absorbed through the skin. If you have any questions or concerns about this medication, it is recommended to consult with your healthcare provider for further guidance.

Other Uses

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This compounded formulation of Ketamine HCl 5%, Gabapentin 10%, Clonidine HCl 0.2%, and Baclofen 2% is presented in a topical gel format. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. This targeted treatment facilitates the absorption of active ingredients directly at the site of discomfort.

The formulation is primarily used for the management of chronic pain conditions, including post-herpetic neuralgia and diabetic neuropathy. It works by reducing inflammation and improving nerve conduction, thereby alleviating pain and discomfort. The inclusion of Baclofen in the formulation also aids in reducing muscle spasms and improving range of motion, which can be particularly beneficial for patients with muscle spasticity.

Another potential use of this formulation is in the management of migraine headaches. It may help to reduce the frequency and intensity of migraines, providing relief to sufferers. However, it is important to note that this formulation may cause skin irritation in some individuals. Therefore, it should be used with caution and under the guidance of a healthcare provider.

If any adverse reactions occur, such as severe skin irritation, patients are advised to discontinue use immediately and contact their healthcare provider. It is always important to use this medication as directed and to discuss any concerns or questions with a healthcare professional.

Frequently Asked Questions

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What is the Ketamine HCl 5%/Gabapentin 10%/Clonidine HCl 0.2%/Baclofen 2% Topical Gel?

This is a compounded formulation of four active ingredients: Ketamine HCl, Gabapentin, Clonidine HCl, and Baclofen. It is a semisolid formulation dispensed through a pump mechanism for easy and precise application on the skin.

How does this topical gel work?

The gel works by delivering the active ingredients directly to the targeted area through the skin. This allows for localized treatment and can help to reduce systemic side effects.

What are the active ingredients in this gel?

The active ingredients in this gel are Ketamine HCl, Gabapentin, Clonidine HCl, and Baclofen. These are medications commonly used for pain management and muscle relaxation.

How should I apply this gel?

This gel should be applied to the skin in the area where treatment is needed. The pump mechanism allows for easy and precise application. Always follow your healthcare provider's instructions for use.

Can I use this gel on broken or irritated skin?

No, this gel should not be applied to broken or irritated skin. If you have any concerns about where to apply the gel, please consult with your healthcare provider.

What should I do if I experience any side effects?

If you experience any side effects, such as skin irritation or an allergic reaction, stop using the gel and contact your healthcare provider immediately.

Can I use this gel with other medications?

Before starting any new medication, including this gel, you should always discuss with your healthcare provider to ensure there are no potential interactions.

How should I store this gel?

This gel should be stored at room temperature, away from heat and direct light. Keep the container tightly closed when not in use.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Is this gel safe for children?

The safety and effectiveness of this gel in children have not been established. Always consult with a healthcare provider before using any new medication in children.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.