Metformin HCl 10% Vaginal Gel

Metformin HCl 10% Vaginal Gel is a prescription medication used to treat Polycystic Ovary Syndrome (PCOS) in women. It helps to reduce the symptoms of PCOS such as irregular or absent menstrual periods, excessive hair growth, acne, and infertility. Metformin works by decreasing the amount of sugar released by the liver and improving the body's response to insulin.
The Bayview Team
Updated on
1.19.2023

Unable to Add
to Order Form

Controlled substances must be E-Prescribed. Visit your Tutorials tab to learn how to prescribe.
Women's Health - Polycystic Ovary Syndrome (PCOS)
Add to Order Form
Women's Health - Polycystic Ovary Syndrome (PCOS)
Want this compounded medication?
Click the Text Us button below.

Formula Information

Metformin HCl 10% Vaginal Gel is a pharmacy-compounded formulation for the treatment of Women’s Health–Polycystic Ovary Syndrome (PCOS). The active ingredient, Metformin HCl, is an oral antidiabetic medication that has been found to regulate the production of androgens by the ovaries, reducing their side effects on the body. This vaginal gel formulation allows direct delivery of the medication to the genital area, avoiding systemic absorption so the patient can receive an optimal dose and benefit from localized direct action. It may help to reduce androgen-related symptoms, such as hirsutism, acne, irregular menstrual cycles, and anxiety. If you have any questions about this formulation, its use for PCOS, or any of its potential side effects, please reach out to us.

Drug Interactions

Metformin HCl 10% Vaginal Gel is a prescription medication used to treat Polycystic Ovary Syndrome (PCOS) in women. It helps to reduce the symptoms of PCOS such as irregular or absent menstrual periods, excessive hair growth, acne, and infertility. Metformin works by decreasing the amount of sugar released by the liver and improving the body's response to insulin.

How Does it Work

Metformin HCl 10% Vaginal Gel (Vyfemla) is a medication developed to treat Women's Health - Polycystic Ovary Syndrome (PCOS). PCOS is a hormonal disorder found in women where their ovaries overproduce androgens, resulting in irregular menstrual cycles, infertility, and other symptoms. Metformin is an anti-diabetic medication that helps reduce high sugar levels in the blood. The HCl 10 percent is the form of metformin used in the vaginal gel and helps the medication penetrate the tissues. Vyfemla works to treat PCOS through two mechanisms. Firstly, it helps reduce androgen levels by inhibiting the liver from releasing glucose into the bloodstream, thereby reducing the levels of androgens. Secondly, it improves insulin sensitivity by stirring up the cells in the ovaries to reduce their production of androgens. This helps normalize the menstrual cycle and reduce infertility in women with PCOS. The vaginal gel works over time to regularly reduce androgen levels. It is usually prescribed as a daily or weekly dose, depending on the severity and nature of the symptoms. In addition to reducing androgen levels, it can also help control other conditions linked to PCOS, such as obesity, diabetes, and cardiovascular diseases. It is important to follow the dosage instructions provided by the doctor as overuse or misuse of this medication can increase the risk of complications.

Other Uses

Metformin HCl 10% Vaginal Gel can be used as an off-label topical treatment to manage some superficial skin conditions such as acne, rosacea, allergic dermatitis, and psoriasis. It can also be used to treat androgenic alopecia and to mitigate symptoms associated with menopause, such as hot flashes and vaginal dryness. Additionally, it has been an effective and relatively safe way to treat bacterial vaginosis, trichomoniasis, and vulvovaginal candidiasis. Lastly, Metformin HCl 10% Vaginal Gel may be beneficial in improving vaginal health as well as maintaining a healthy balance of vaginal flora.
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

Metformin HCl 10% Vaginal Gel

Metformin HCl 10% Vaginal Gel is a prescription medication used to treat Polycystic Ovary Syndrome (PCOS) in women. It helps to reduce the symptoms of PCOS such as irregular or absent menstrual periods, excessive hair growth, acne, and infertility. Metformin works by decreasing the amount of sugar released by the liver and improving the body's response to insulin.
The Bayview Team
Updated
1/19/2023

Unable to Add
to Order Form

Want this compounded medication?
Click the Text Us button below.

Formula Information

Metformin HCl 10% Vaginal Gel is a pharmacy-compounded formulation for the treatment of Women’s Health–Polycystic Ovary Syndrome (PCOS). The active ingredient, Metformin HCl, is an oral antidiabetic medication that has been found to regulate the production of androgens by the ovaries, reducing their side effects on the body. This vaginal gel formulation allows direct delivery of the medication to the genital area, avoiding systemic absorption so the patient can receive an optimal dose and benefit from localized direct action. It may help to reduce androgen-related symptoms, such as hirsutism, acne, irregular menstrual cycles, and anxiety. If you have any questions about this formulation, its use for PCOS, or any of its potential side effects, please reach out to us.

Drug Interactions

Metformin HCl 10% Vaginal Gel is a prescription medication used to treat Polycystic Ovary Syndrome (PCOS) in women. It helps to reduce the symptoms of PCOS such as irregular or absent menstrual periods, excessive hair growth, acne, and infertility. Metformin works by decreasing the amount of sugar released by the liver and improving the body's response to insulin.

How Does it Work

Metformin HCl 10% Vaginal Gel (Vyfemla) is a medication developed to treat Women's Health - Polycystic Ovary Syndrome (PCOS). PCOS is a hormonal disorder found in women where their ovaries overproduce androgens, resulting in irregular menstrual cycles, infertility, and other symptoms. Metformin is an anti-diabetic medication that helps reduce high sugar levels in the blood. The HCl 10 percent is the form of metformin used in the vaginal gel and helps the medication penetrate the tissues. Vyfemla works to treat PCOS through two mechanisms. Firstly, it helps reduce androgen levels by inhibiting the liver from releasing glucose into the bloodstream, thereby reducing the levels of androgens. Secondly, it improves insulin sensitivity by stirring up the cells in the ovaries to reduce their production of androgens. This helps normalize the menstrual cycle and reduce infertility in women with PCOS. The vaginal gel works over time to regularly reduce androgen levels. It is usually prescribed as a daily or weekly dose, depending on the severity and nature of the symptoms. In addition to reducing androgen levels, it can also help control other conditions linked to PCOS, such as obesity, diabetes, and cardiovascular diseases. It is important to follow the dosage instructions provided by the doctor as overuse or misuse of this medication can increase the risk of complications.

Other Uses

Metformin HCl 10% Vaginal Gel can be used as an off-label topical treatment to manage some superficial skin conditions such as acne, rosacea, allergic dermatitis, and psoriasis. It can also be used to treat androgenic alopecia and to mitigate symptoms associated with menopause, such as hot flashes and vaginal dryness. Additionally, it has been an effective and relatively safe way to treat bacterial vaginosis, trichomoniasis, and vulvovaginal candidiasis. Lastly, Metformin HCl 10% Vaginal Gel may be beneficial in improving vaginal health as well as maintaining a healthy balance of vaginal flora.
Want this compounded medication? Click the Text Us button.