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Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray

FDA-approved generic
Dose form
Nasal Spray
Active ingredients
Phenylephrine Hydrochloride
Tetracaine Hydrochloride

The Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray is a compounded liquid formulation intended for intranasal administration. Phenylephrine, a potent vasoconstrictor, is used to decrease nasal congestion by narrowing the blood vessels in the nasal passages, thereby providing relief from the symptoms of nasal congestion associated with colds, sinusitis, and allergic rhinitis. Tetracaine, a local anesthetic, is included to provide temporary relief of nasal discomfort due to minor irritations or to anesthetize the mucous membranes for diagnostic procedures or surgeries. The combination of these two active ingredients in a nasal spray form allows for rapid onset of action and targeted delivery to the nasal cavity for both local and systemic therapeutic effects.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Phenylephrine Hydrochloride
Tetracaine Hydrochloride
Nasal Spray
65cd16c876dac9c2e873d3e8
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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The Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray is a compounded medication that combines the vasoconstrictive properties of Phenylephrine with the local anesthetic effects of Tetracaine. This liquid formulation is specifically designed for nasal administration, providing a convenient and efficient method for delivering medication directly to the site of action. The spray form ensures a consistent and controlled dose with each administration, which is important for both safety and efficacy.

Phenylephrine HCL is a selective alpha-1 adrenergic receptor agonist, which induces vasoconstriction when applied to the nasal mucosa. This action reduces nasal congestion by constricting the dilated blood vessels in the nasal passages, thereby providing relief from the symptoms of nasal congestion commonly associated with colds, sinusitis, and allergic rhinitis. The decongestant effect of Phenylephrine also improves the penetration of Tetracaine into the nasal tissues, enhancing its efficacy.

Tetracaine HCL is a potent local anesthetic that provides rapid and long-lasting numbness to the area of application. In this formulation, Tetracaine is used to anesthetize the nasal mucosa, which can be beneficial for procedures that require nasal instrumentation or to alleviate pain from various nasal conditions. The combination of Phenylephrine and Tetracaine in a nasal spray form is particularly useful for pre-procedural anesthesia in the outpatient setting, such as before diagnostic nasal endoscopy or minor surgical interventions.

It is important for patients and prescribers to note that this compounded formulation should be used with caution in patients with cardiovascular disease, hypertension, hyperthyroidism, diabetes, or those taking monoamine oxidase inhibitors (MAOIs), due to the potential systemic effects of Phenylephrine. Additionally, Tetracaine should be used with caution in patients with a history of hypersensitivity to ester-type local anesthetics. The use of this nasal spray should be individualized based on the patient's medical history and the intended use of the medication.

For prescribers considering this formulation for their patients, it is essential to provide a comprehensive medical history and to discuss the potential benefits and risks associated with the use of Phenylephrine HCL and Tetracaine HCL nasal spray. Patients should be instructed on the proper use of the nasal spray, including the recommended dosage and administration technique, to ensure optimal results and minimize potential side effects.

If you have any questions or require further information about the Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing the highest quality of care and is available to assist with any inquiries you may have regarding this specialized formulation.

Drug Interactions

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The Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray is a compounded medication that combines a decongestant (phenylephrine) and a local anesthetic (tetracaine) for use in the nasal cavity. Phenylephrine works by constricting blood vessels in the nasal passages, reducing swelling and congestion. Tetracaine provides local anesthesia by blocking nerve signals in the nasal tissue. This formulation is used for various conditions that require nasal decongestion and local anesthesia, such as during diagnostic procedures, before minor surgeries, or to alleviate symptoms of certain nasal conditions.

When considering drug interactions, it is important to note that phenylephrine is an alpha-1 adrenergic receptor agonist and can interact with several classes of medications. Monoamine oxidase inhibitors (MAOIs) can potentiate the effects of phenylephrine, leading to hypertensive crises. Therefore, patients taking MAOIs should avoid this nasal spray or use it with extreme caution. Beta-blockers may also interact with phenylephrine, as they can negate the beta-blocking effects, potentially leading to increased blood pressure and heart rate. Caution is advised when using this spray in patients on antihypertensive medications, as phenylephrine can reduce their effectiveness.

Tetracaine, being a local anesthetic, can interact with other local anesthetics, potentially increasing the risk of systemic toxicity, especially if used in large amounts or more frequently than recommended. It is also important to consider the use of this nasal spray in patients taking class III antiarrhythmic drugs (such as amiodarone), as the combination may increase the risk of cardiac side effects. Additionally, medications that inhibit plasma cholinesterase, such as certain cholinesterase inhibitors and some anticholinergic drugs, can prolong and enhance the effects of tetracaine.

Patients should be advised to inform their healthcare provider of all medications they are taking, including over-the-counter drugs, herbal supplements, and vitamins, to avoid potential interactions. It is also important to use this nasal spray only as directed by a healthcare professional and to report any unusual side effects or symptoms immediately. If you have any questions or concerns regarding the use of Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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The Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray is a compounded medication that combines two active pharmaceutical ingredients (APIs) to provide both decongestant and local anesthetic effects for patients requiring nasal relief. This liquid formulation is designed to be administered directly into the nasal cavity using a spray mechanism, which allows for precise dosing and targeted delivery to the site of action.

Phenylephrine HCL is a sympathomimetic agent that works primarily as a selective alpha-1 adrenergic receptor agonist. When sprayed into the nasal passages, phenylephrine causes vasoconstriction, which leads to a reduction in the swelling of the nasal mucosa. This action helps to alleviate nasal congestion and improves airflow through the nostrils. Phenylephrine is commonly used to relieve the symptoms of nasal congestion associated with allergies, sinusitis, or the common cold. Its effects are localized to the site of application, minimizing systemic absorption and reducing the likelihood of systemic side effects.

Tetracaine HCL, on the other hand, is a potent local anesthetic that works by blocking sodium channels required for the initiation and conduction of neuronal impulses. When applied to the nasal mucosa, tetracaine provides localized pain relief by numbing the area. This can be particularly beneficial for procedures that require the insertion of nasal instruments or for patients experiencing significant nasal pain due to various conditions.

The combination of phenylephrine and tetracaine in a nasal spray form offers the convenience of treating both congestion and pain in the nasal passages simultaneously. The spray formulation allows for easy self-administration by the patient and ensures that the medication is delivered directly to the affected area, providing rapid onset of action. The liquid is atomized into a fine mist upon activation of the spray pump, ensuring even distribution along the nasal mucosa for optimal therapeutic effect.

This compounded nasal spray is typically used in an outpatient setting, such as a doctor's office or at home, under the guidance of a healthcare professional. It is important for patients and prescribers to understand the proper use of this medication, including the correct dosing and administration technique, to ensure safety and efficacy. As with any medication, there may be potential side effects, and it is crucial to monitor the patient's response to therapy.

If you have any questions or require further information about the Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to both patients and prescribers to ensure the best possible outcomes with this formulation.

Frequently Asked Questions

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What is Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray?

This is a compounded medication that combines two drugs: phenylephrine hydrochloride, a decongestant, and tetracaine hydrochloride, a local anesthetic. It is administered as a liquid spray into the nasal cavity to provide targeted relief or systemic effects.

How does the Phenylephrine HCL/Tetracaine HCL Nasal Spray work?

Phenylephrine HCL works by constricting blood vessels in the nasal passages, reducing congestion and swelling. Tetracaine HCL acts as a local anesthetic to numb the nasal mucous membranes, providing pain relief.

Is this nasal spray safe for children to use?

The safety of this nasal spray for children depends on their age, medical condition, and response to treatment. It's important to consult with a healthcare provider before using this medication for a child.

How often can I use this nasal spray?

Usage frequency should be as directed by a healthcare provider. Do not exceed the recommended dose or frequency to avoid possible side effects or overdose.

Can this nasal spray be used for allergies?

While this nasal spray has a decongestant component that may alleviate symptoms related to nasal allergies, it is best to consult with a healthcare provider about its use for allergy treatment, as its formulation also contains a local anesthetic.

Are there any potential side effects of using this nasal spray?

Yes, potential side effects may include nasal irritation or dryness, sneezing, headache, or a temporary burning sensation in the nose. Serious side effects are rare but can occur. If you experience any severe reactions, seek medical attention promptly.

Can I use Phenylephrine HCL/Tetracaine HCL Nasal Spray if I am pregnant or breastfeeding?

You should consult with your healthcare provider before using this nasal spray if you are pregnant or breastfeeding, as some of its ingredients may not be recommended.

Does this nasal spray interact with other medications?

There may be potential interactions with other medications, particularly those that may increase the risk of side effects such as elevated blood pressure or heart rate. It's important to disclose all medications you are taking with your healthcare provider prior to using this nasal spray.

How should I store this nasal spray?

Store this nasal spray at room temperature away from light and moisture. Keep it out of reach of children and pets. Do not freeze the medication, and discard it properly after the expiration date or when advised by a healthcare provider.

What should I do in case of an overdose?

If you suspect an overdose, or experience severe side effects such as trouble breathing or chest pain, seek immediate medical attention or contact your local poison control center.

Can the nasal spray be used for chronic sinus issues?

While it may provide temporary relief for sinus symptoms, it's crucial to consult with a healthcare provider for a proper diagnosis and long-term management plan for chronic sinus issues. Overuse or misuse of nasal sprays can worsen symptoms or lead to additional health problems.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Phenylephrine HCL 0.5%/Tetracaine HCL 2.276% Nasal Spray
Nasal Spray
10 mL
controlled

Inhale intranasally

Twice daily