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The Podophyllum Resin 25% in Tincture of Benzoin Topical Liquid is a specially crafted preparation intended for external application. This formulation leverages the keratolytic and antimitotic properties of podophyllum resin, effectively used in the treatment of plantar warts, genital warts, and other benign growths such as molluscum contagiosum. The tincture of benzoin serves as a vehicle that enhances the adhesion of the preparation to the skin, providing a protective layer and extending the contact time of the active ingredient with the lesion. This topical liquid is particularly beneficial for patients requiring localized therapy directly at the site of the lesion, minimizing systemic absorption and side effects.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Podophyllum Resin 25% in Tincture of Benzoin Topical Liquid is a specialized dermatological preparation intended for external use on skin or mucosal surfaces. This formulation combines the potent cytotoxic and antimitotic properties of Podophyllum resin, derived from the roots and rhizomes of the Podophyllum plant, with the protective and adhesive characteristics of Tincture of Benzoin. The concentration of Podophyllum resin at 25% ensures a high level of efficacy against various skin conditions, while the Tincture of Benzoin provides a barrier to protect the affected area and enhance the adhesion of the resin to the skin.
It works by arresting the cell division in the warts, leading to the death of the wart tissue. Additionally, this formulation may be employed in the management of other skin conditions such as molluscum contagiosum and plantar warts, although these uses are less common and should be guided by a healthcare professional. The Tincture of Benzoin component not only helps in securing the resin in place but also has mild antiseptic properties that may reduce the risk of secondary infections.
Patients should be advised that this preparation is for external use only and must be applied with precision to the affected area to avoid irritation to surrounding healthy tissue. It is important to follow the specific application instructions provided by the prescriber to minimize side effects and maximize therapeutic outcomes. Common side effects may include local irritation, redness, and in some cases, systemic toxicity if applied over large areas of the body or used improperly. Therefore, it is crucial to adhere to the prescribed frequency and duration of treatment.
Prescribers opting for this formulation should consider the patient's medical history, current medications, and potential for allergic reactions. Due to the nature of the active ingredients, this preparation should not be used in pregnant or breastfeeding women, and caution is advised when treating pediatric patients. It is also important to monitor the treatment progress and any adverse effects, adjusting the therapy as necessary.
At Bayview Pharmacy, we are committed to providing high-quality compounded medications tailored to the specific needs of our patients. Our team of knowledgeable compounding pharmacists is available to answer any questions and provide guidance on the use of Podophyllum Resin 25% in Tincture of Benzoin Topical Liquid. If you have any questions or require further information, please do not hesitate to reach out to us.
The Podophyllum Resin 25% in Tincture of Benzoin Topical Liquid is a specialized formulation intended for direct application to the skin or mucosal surfaces. Podophyllum resin, derived from the roots of the Podophyllum plant, is used primarily for its antimitotic properties. Tincture of Benzoin is commonly used as a skin protectant and adhesive agent.
When considering drug interactions, it is important to note that while the systemic absorption of this topical formulation is minimal, there may still be potential interactions with other topically applied medications. Concurrent use of other topical agents on the same treatment area should be approached with caution, as there may be additive effects or altered absorption. For example, the use of other keratolytic agents (such as salicylic acid) in conjunction with this formulation may increase the risk of local irritation or skin damage.
Patients should be advised to avoid applying other topical preparations, especially those containing alcohol or astringents, to the affected area unless directed by a healthcare provider, as these could potentially cause increased irritation or dryness. Additionally, occlusive dressings should not be used over the area treated with Podophyllum Resin 25% in Tincture of Benzoin Topical Liquid unless specifically instructed by a healthcare provider, as this may increase the absorption of podophyllin and the risk of systemic toxicity.
It is also important to consider the potential for systemic interactions if there is significant absorption of podophyllin. Although rare, systemic absorption can occur, especially when applied to large surface areas or to mucosal membranes. Patients should be monitored for symptoms of systemic toxicity, such as nausea, vomiting, diarrhea, and neuropathy. If systemic toxicity is suspected, the use of this formulation should be discontinued immediately.
Patients who are pregnant, breastfeeding, or planning to become pregnant should consult with a healthcare provider before using this formulation, as podophyllin can be systemically absorbed and may cause harm to the fetus or nursing infant. Additionally, patients with pre-existing peripheral neuropathy or those taking drugs that can cause neuropathy (such as certain chemotherapeutic agents) should use this formulation with caution and under close supervision by a healthcare provider.
As with all medications, it is essential to use this formulation as directed by a healthcare provider and to report any unusual symptoms or suspected interactions. If you have any questions or concerns regarding the use of Podophyllum Resin 25% in Tincture of Benzoin Topical Liquid, or if you require further information about potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and appropriate use of this medication.
The Podophyllum Resin 25% in Tincture of Benzoin Topical Liquid is a specialized formulation that combines the potent keratolytic and antimitotic properties of podophyllum resin with the protective and adhesive characteristics of tincture of benzoin. This preparation is specifically designed for direct application to the skin or mucosal surfaces, where it exerts its therapeutic effects locally without significant systemic absorption. This is particularly beneficial for patients who require treatment at specific sites and wish to minimize potential systemic side effects.
Podophyllum resin, derived from the roots and rhizomes of the Podophyllum plant, contains active components such as podophyllotoxin. Podophyllotoxin works by inhibiting cell division (mitosis) at the metaphase stage. By arresting the growth of these cells, podophyllum resin helps to reduce the size and number of warts, eventually leading to their removal. It is commonly used to treat conditions like plantar warts, genital warts, and other verrucae.
Tincture of Benzoin, on the other hand, is a solution of benzoin resin in alcohol that acts as a skin protectant and adhesive. When applied to the skin, it provides a sticky coating that not only protects the affected area from irritation but also ensures that the podophyllum resin stays in place, allowing for optimal contact time and enhanced efficacy of the treatment. The combination of these two components in a single formulation allows for a synergistic effect, maximizing the therapeutic benefits while minimizing potential irritation and damage to the surrounding healthy skin.
It is important for patients and prescribers to understand that this formulation should be used with caution, as podophyllum resin is a potent agent that can cause local irritation and even systemic toxicity if used improperly. The application should be precise, targeting only the affected area, and it should be applied by a healthcare professional or under their guidance. The frequency and duration of application are also critical factors that need to be tailored to the individual's condition and response to treatment.
For further information or if you have any questions regarding the use of Podophyllum Resin 25% in Tincture of Benzoin Topical Liquid, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and appropriate use of this formulation.
Podophyllum Resin 25% in Tincture of Benzoin Topical Liquid is used for the treatment of various skin lesions, including warts (such as plantar warts and genital warts). It works by stopping the growth of unwanted tissue.
It should be applied directly to the affected area of the skin with a provided applicator or a small brush. Care should be taken to apply it only to the lesion and not the surrounding healthy skin, as it can be irritating.
No, you should only use it for conditions that your healthcare provider specifically prescribes it for, as it is potent and designed for particular types of skin lesions like warts.
Frequency of use should be as directed by your healthcare provider. Often, it is applied once daily or a few times a week, but your specific regimen may differ.
If it contacts healthy skin or mucous membranes, wash the area immediately with soap and water and protect the area from light until the residue is completely washed off.
This medication may not be safe during pregnancy. If you are pregnant, think you may be pregnant, or plan to become pregnant, you should inform your healthcare provider before starting treatment.
You should avoid exposure to sunlight and UV light on the treated areas since podophyllum resin can make your skin more sensitive to UV light. Protect the area with clothing if going outside is necessary.
Possible side effects can include local irritation, redness, burning, pain, and, in extreme cases, systemic toxicity if applied over large areas or used improperly. Contact your healthcare provider if severe side effects occur.
The time to see improvement varies depending on the size and type of the lesion. It can take several weeks of treatment to see significant results. Your healthcare provider will assess the progress in follow-up visits.
Its use in children should be under strict medical supervision. Due to higher absorption rates in children, they are more susceptible to systemic toxicity, and caution is advised.
Store it in a cool, dry place away from direct sunlight and out of reach of children. Do not freeze, and keep the bottle tightly closed when not in use.
If an overdose is suspected, particularly if excessive skin irritation or any signs of systemic toxicity occur, you should contact your healthcare provider or local poison control center immediately for guidance.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
