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Formulas

Selegiline HCl 1.25 mg Oral Capsules

FDA-approved generic
Dose form
Capsules
Active ingredients
Selegiline Hydrochloride

Selegiline HCl 1.25 mg Oral Capsules are a solid dosage form consisting of two halves of either gelatin or vegetarian-based shells that encapsulate the medication. This design ensures the capsules are easy to swallow and that each dose contains an exact amount of the active ingredient, Selegiline Hydrochloride. Selegiline is primarily used in the treatment of Parkinson's disease as it aids in the management of motor symptoms associated with this condition. Additionally, it may be prescribed for patients with major depressive disorder as an adjunct treatment. The precise 1.25 mg dosage of Selegiline within these capsules is intended for titration or maintenance therapy, as directed by a healthcare professional.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Selegiline Hydrochloride
Capsules
65d527ccfe3327ad38bb85c7
Service area

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Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Selegiline HCl 1.25 mg Oral Capsules are a solid dosage form consisting of two halves of either gelatin or vegetarian-based shells that encapsulate the medication. This form of medication is designed to be swallowed easily and to ensure that patients receive an exact dose of Selegiline Hydrochloride, which is crucial for its effectiveness and safety. Selegiline is a selective monoamine oxidase inhibitor (MAOI), specifically inhibiting the enzyme monoamine oxidase type B (MAO-B). This enzyme is responsible for the breakdown of dopamine in the brain. By inhibiting MAO-B, Selegiline increases the levels of dopamine, which can help alleviate symptoms associated with Parkinson's disease and major depressive disorder.

In the treatment of Parkinson's disease, Selegiline is often used as an adjunct to levodopa/carbidopa therapy. It can help to enhance and prolong the effects of levodopa, which may lead to an improvement in the control of motor fluctuations and a reduction in 'off' periods during which the medication's effects wear off and symptoms return. For depression, Selegiline's MAO-B inhibiting action can also lead to an increase in the levels of other neurotransmitters, such as phenethylamine and possibly serotonin and norepinephrine, which may contribute to its antidepressant effects.

It is important for patients and prescribers to be aware that Selegiline may interact with certain medications, including other antidepressants, and can have contraindications in certain medical conditions. Dietary restrictions may also be necessary to avoid hypertensive crises when higher doses are used, although at the 1.25 mg dosage, these restrictions are typically not required. Monitoring for side effects, such as orthostatic hypotension, insomnia, or confusion, is also important. As with any medication, adherence to prescribed dosing schedules is essential for optimal outcomes.

For those considering Selegiline HCl 1.25 mg Oral Capsules, it is crucial to consult with a healthcare provider to determine if this medication is appropriate for your specific condition and to discuss any potential interactions with other medications you may be taking. If you have any questions or require further information about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing you with the necessary support and guidance to ensure appropriate treatment with Selegiline HCl.

Drug Interactions

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Selegiline HCl (hydrochloride) is a monoamine oxidase inhibitor (MAOI) that is primarily used to treat Parkinson's disease and, in some cases, major depressive disorder. It works by inhibiting the enzyme monoamine oxidase type B (MAO-B), which breaks down dopamine in the brain, thereby increasing the levels of dopamine and helping to improve motor symptoms in Parkinson's disease. When used for depression, it inhibits MAO-A and MAO-B to varying degrees, depending on the dose, which can lead to increased levels of neurotransmitters such as serotonin and norepinephrine.

When considering the use of Selegiline HCl 1.25 mg oral capsules, it is crucial to be aware of potential drug interactions that can lead to serious adverse effects or reduced therapeutic efficacy. Selegiline should not be used concomitantly with other MAOIs, as this can lead to a hypertensive crisis or serotonin syndrome, a potentially life-threatening condition. Additionally, the use of Selegiline with serotonergic drugs, such as SSRIs, SNRIs, tricyclic antidepressants, or St. John's Wort, should be approached with caution and may require a washout period to avoid serotonin syndrome.

Patients should also avoid the use of sympathomimetic amines, including over-the-counter cold, allergy, and cough medications containing ephedrine or pseudoephedrine, as these can lead to hypertensive reactions when taken with Selegiline. The use of opioid medications, particularly meperidine, tramadol, methadone, and propoxyphene, should be avoided due to the risk of serious and potentially fatal reactions. Additionally, Selegiline can potentiate the effects of levodopa and may require a reduction in levodopa dosage to avoid exacerbating dopaminergic side effects such as dyskinesias.

Patients should also be advised to avoid foods and beverages high in tyramine, as Selegiline can inhibit MAO-A at higher doses, leading to the risk of hypertensive crisis when tyramine-containing foods are consumed. Foods to avoid include aged cheeses, cured meats, fermented products, soy sauce, tap beers, and red wine. Furthermore, antihypertensive medications may require dosage adjustments due to potential additive hypotensive effects when used with Selegiline.

It is important to inform healthcare providers of all medications, supplements, and herbal products being taken before starting Selegiline to avoid harmful interactions. Patients should be monitored closely for any adverse reactions, especially when initiating or discontinuing drugs that may interact with Selegiline. If you have any questions or concerns regarding the use of Selegiline HCl 1.25 mg oral capsules or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Selegiline HCl (hydrochloride) is an oral medication that belongs to a class of drugs known as monoamine oxidase inhibitors (MAOIs). Specifically, selegiline is a selective inhibitor of monoamine oxidase type B (MAO-B). This enzyme is responsible for the breakdown of dopamine, a neurotransmitter that plays a key role in motivation, pleasure, and motor control. By inhibiting MAO-B, selegiline increases the levels of dopamine in the brain, which can help to alleviate symptoms associated with Parkinson's disease and major depressive disorder.

In the treatment of Parkinson's disease, selegiline is used as an adjunct to levodopa/carbidopa therapy. It can help to enhance and prolong the effects of levodopa, which is the precursor to dopamine and is commonly used to treat Parkinson's symptoms. By increasing dopamine levels, selegiline can help to improve motor function and reduce the 'wearing-off' effect that some patients experience as the effects of levodopa diminish. It is important to note that selegiline is not a cure for Parkinson's disease, but it can help to manage symptoms and improve quality of life for patients.

For the treatment of major depressive disorder, selegiline in higher doses has been shown to have antidepressant properties. It is thought that the increase in dopamine, as well as other neurotransmitters like serotonin and norepinephrine, can help to alleviate depressive symptoms. However, the 1.25 mg dosage of selegiline is typically used for Parkinson's disease, and higher doses would be required for the treatment of depression.

The selegiline HCl 1.25 mg oral capsules provided by Bayview Pharmacy are a solid dosage form consisting of two gelatin or vegetarian shells that enclose the medication. These capsules are designed to be swallowed whole, releasing the selegiline in the stomach where it is absorbed into the bloodstream. The capsule form ensures a precise dosage of the active ingredient, which is crucial for maintaining the desired therapeutic effect while minimizing the risk of side effects. Additionally, the encapsulated form of the medication can help to protect the active ingredient from degradation and improve its shelf life.

It is important for patients and prescribers to be aware of potential interactions with other medications and substances when using selegiline. For example, combining selegiline with certain antidepressants or consuming foods high in tyramine can lead to serious side effects. Therefore, it is essential to follow the guidance of a healthcare professional when using this medication.

If you have any questions about the selegiline HCl 1.25 mg oral capsules or how they work in treating Parkinson's disease or other conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure appropriate treatment.

Frequently Asked Questions

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What is Selegiline HCl 1.25 mg Oral Capsule?

Selegiline HCl 1.25 mg Oral Capsule is a medication used in the treatment of Parkinson's disease and sometimes major depressive disorder. It works by increasing the levels of certain chemicals in the brain that help to alleviate symptoms of these conditions.

How should I take Selegiline HCl 1.25 mg Oral Capsules?

Selegiline HCl 1.25 mg Oral Capsules should be taken orally as directed by your healthcare professional, usually once or twice daily. Swallow the capsules whole with water; do not crush or chew them.

What are the solid dosage forms composed of?

Solid dosage forms are composed of two gelatin or vegetarian shells that enclose medication. These are known as capsules, designed to make swallowing easier and to ensure precise dosage of the active ingredients.

Can I open the Selegiline HCl capsule and mix it with food?

No, Selegiline HCl capsules should not be opened or crushed. They are designed to be swallowed whole in order to ensure the proper release and absorption of the medication.

Are these capsules suitable for vegetarians?

It depends on the composition of the capsule shells. If the shell is made from vegetarian sources, then it is suitable for vegetarians. It's important to check the label or consult with your pharmacist or healthcare provider.

What storage conditions do Selegiline HCl 1.25 mg Oral Capsules require?

Selegiline HCl Oral Capsules should be stored at room temperature, away from light and moisture. Keep the bottle tightly closed when not in use and keep out of reach of children and pets.

What should I do if I miss a dose of Selegiline HCl 1.25 mg Oral Capsules?

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Can Selegiline HCl 1.25 mg Oral Capsules cause side effects?

Yes, as with any medication, Selegiline HCl can cause side effects. Common side effects include dry mouth, nausea, dizziness, or abdominal pain. If you experience severe or persistent side effects, contact your healthcare provider immediately.

Is there anyone who should not take Selegiline HCl 1.25 mg Oral Capsules?

Certain individuals, such as those with allergies to selegiline or its components, those with a history of certain medical conditions, or those taking certain medications, should not take Selegiline HCl without consulting a healthcare provider.

Do I need a prescription to obtain Selegiline HCl 1.25 mg Oral Capsules?

Yes, Selegiline HCl is a prescription medication. You will need to obtain a prescription from a licensed healthcare provider to purchase this medication.

How do I know if Selegiline HCl 1.25 mg Oral Capsules are working?

You may notice an improvement in the symptoms of your condition, such as increased mobility and decreased episodes of immobility. Your healthcare provider may also perform evaluations or tests to assess the effectiveness of the treatment. It’s important to communicate with your provider about your response to the medication.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Selegiline HCl 1.25 mg Oral Capsules
Capsules
90 capsules
controlled

Take 1 capsule by mouth

Once daily in the morning