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Description: This Sodium Benzoate 3 g/15 mL Oral Liquid is a specially compounded medication designed for oral use. The liquid formulation ensures ease of ingestion and precise dosing, particularly beneficial for patients who have difficulty swallowing solid dosage forms, including pediatric and geriatric populations. Sodium benzoate is commonly used in the treatment of hyperammonemia, which is an elevated ammonia level in the blood, often associated with urea cycle disorders. It acts by aiding in the excretion of ammonia from the body. This oral liquid medication provides a critical therapeutic option for managing this condition.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Sodium Benzoate 3 g/15 mL Oral Liquid is a custom-prepared medication specifically designed for patients who require sodium benzoate in a liquid form for ease of administration. This formulation is particularly beneficial for individuals who have difficulty swallowing pills, such as children and the elderly, or for those with conditions that impair their ability to ingest solid dosage forms. The concentration of sodium benzoate in this preparation ensures that each 15 mL of the oral liquid contains 3 grams of the active ingredient, allowing for precise dosing as prescribed by a healthcare provider.
Sodium benzoate is commonly used as a treatment for urea cycle disorders (UCDs), which are genetic conditions that result in a deficiency of one of the enzymes in the urea cycle. This deficiency leads to an accumulation of ammonia in the blood, which can cause serious health issues, including neurological damage. Sodium benzoate works by providing an alternative pathway for the excretion of nitrogen, by conjugating with glycine to form hippurate, which is then excreted in the urine. This action helps to reduce the levels of ammonia in the blood, thereby alleviating the symptoms associated with UCDs.
It is important for both patients and prescribers to understand that the effectiveness of Sodium Benzoate 3 g/15 mL Oral Liquid is dependent on accurate dosing and adherence to the prescribed regimen. The liquid formulation allows for flexible dosing adjustments and can be mixed with water or other suitable liquids as advised by a healthcare professional to improve palatability. As with any medication, potential side effects may occur, and it is essential to monitor the patient's response to therapy and adjust the treatment as necessary.
Bayview Pharmacy's team of compounding pharmacists is dedicated to providing high-quality, customized medications to meet the unique needs of each patient. We are available to answer any questions and provide additional information to ensure the safe and appropriate use of Sodium Benzoate 3 g/15 mL Oral Liquid. If you have any questions or require further assistance, please do not hesitate to reach out to us.
Sodium benzoate is a preservative and is also used as a medication to treat a variety of conditions, including urea cycle disorders, where it acts by binding to amino acids and helping to remove ammonia from the body. When considering the use of sodium benzoate 3 g/15 mL oral liquid, it is important to be aware of potential drug interactions that may affect the efficacy of the treatment or cause adverse effects.
One key interaction is with levodopa, a medication used to treat Parkinson's disease. Sodium benzoate may decrease the absorption of levodopa in the intestine, potentially reducing its effectiveness. Patients taking levodopa should consult their healthcare provider before starting sodium benzoate. Additionally, care should be taken when sodium benzoate is used concurrently with other medications that can affect ammonia levels or renal function, such as valproic acid or other anticonvulsants, as there may be an increased risk of hyperammonemia.
Furthermore, patients with a history of hypersensitivity to benzoates should avoid this formulation, as it may provoke allergic reactions. Sodium benzoate is also known to interact with certain food dyes and additives, which can lead to increased levels of benzene, a known carcinogen, when combined in the presence of vitamin C (ascorbic acid). Therefore, it is advisable to avoid taking this medication with foods or supplements containing vitamin C or ascorbic acid.
It is also important to consider the sodium content in patients on a sodium-restricted diet, such as those with hypertension, heart failure, or renal impairment. The additional sodium intake from the medication could exacerbate these conditions. Patients should be monitored for sodium overload and fluid retention.
As with any medication, it is crucial to inform your healthcare provider of all the medications, supplements, and herbal products you are currently taking to avoid potential interactions. If you have any questions or concerns about the use of sodium benzoate 3 g/15 mL oral liquid or its interactions with other substances, please reach out to us at Bayview Pharmacy for further assistance and personalized advice.
The Sodium Benzoate 3 g/15 mL Oral Liquid is a specially crafted medication designed for ease of administration and precise dosing. Sodium benzoate is the sodium salt of benzoic acid and is commonly used as a preservative in the food industry. However, in a medical context, sodium benzoate has a different application. It works by converting to benzoic acid in the stomach, which is then absorbed and metabolized by the liver. The key therapeutic action of sodium benzoate is its ability to conjugate with amino acids, particularly glycine, to form hippuric acid, which is then excreted in the urine.
This biochemical reaction is particularly useful in the treatment of hyperammonemia, a condition characterized by elevated levels of ammonia in the blood. Hyperammonemia can be caused by various disorders, such as urea cycle disorders (UCDs), liver disease, and other metabolic conditions. Ammonia is a toxic byproduct of protein metabolism, and elevated levels can lead to neurological impairment and other serious health issues. By promoting the excretion of ammonia in the form of hippuric acid, sodium benzoate helps to reduce the levels of ammonia in the blood, thereby alleviating the symptoms associated with hyperammonemia.
The oral liquid formulation of sodium benzoate is particularly beneficial for patients who have difficulty swallowing pills, such as young children, the elderly, or those with neurological disorders or esophageal complications. The liquid form allows for flexible dosing, which can be easily adjusted according to the specific needs of the patient. Additionally, the liquid formulation ensures that the medication is readily absorbed and begins to work quickly to reduce ammonia levels in the body.
For prescribers, it is important to note that the dosage of sodium benzoate must be carefully calculated based on the patient's weight and the severity of their condition. Regular monitoring of ammonia levels and liver function tests are recommended to ensure the effectiveness of the treatment and to adjust the dose as necessary. It is also crucial to consider the patient's dietary protein intake, as this can affect ammonia levels and the dosage requirements of sodium benzoate.
Patients and prescribers should be aware of potential side effects, which may include gastrointestinal disturbances, such as nausea or vomiting, and in rare cases, neurological symptoms. As with any medication, it is essential to discuss the potential risks and benefits with a healthcare provider before starting treatment.
If you have any questions or require further information about the Sodium Benzoate 3 g/15 mL Oral Liquid formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing support and guidance to ensure the safe and appropriate use of this medication.
Sodium Benzoate Oral Liquid is a medication commonly prescribed to treat a variety of conditions that require a reduction in the level of ammonia in the blood, such as urea cycle disorders. It is also used in other conditions as determined by a healthcare provider.
The liquid should be measured with an appropriate measuring device to ensure the correct dose is administered. The medication can be taken with or without food, as instructed by your healthcare provider. Follow the prescribed dosing schedule closely.
Liquid forms are particularly beneficial for patients who have difficulties swallowing pills, such as children and the elderly. It also allows for precise dosing adjustments and easier ingestion.
Yes, the liquid can often be mixed with certain foods or beverages to improve palatability. However, it's important to consult with your healthcare provider or pharmacist for instructions regarding specific food and beverage interactions.
If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Like all medications, Sodium Benzoate Oral Liquid can cause side effects. While many people do not experience major side effects, some common ones include nausea, vomiting, and dizziness. If you experience any severe side effects or signs of an allergic reaction, seek medical attention immediately.
The medication should be stored at room temperature, away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets, and never reuse or recycle old containers for new medications.
It is essential to inform your healthcare provider if you are pregnant or plan to become pregnant, or if you are breastfeeding, before using Sodium Benzoate Oral Liquid. They will determine if the benefits outweigh any potential risks to the baby.
Yes, the liquid form is often prescribed for children who are unable to swallow pills. Nevertheless, dosages for pediatric patients are typically different than those for adults, so a healthcare provider’s guidance is crucial.
Yes, Sodium Benzoate Oral Liquid is a medication that requires a prescription from a licensed healthcare provider, as it must be used under medical supervision.
While on Sodium Benzoate Oral Liquid, you should avoid consuming alcohol, as it can increase the risk of side effects. Additionally, discuss with your healthcare provider any other specific dietary restrictions or interactions with other medications or supplements you are taking.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Take orally
