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Testosterone 25 mg/ml Transdermal Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Testosterone

The Testosterone 25 mg/ml Transdermal Gel is a semisolid formulation designed for the treatment of conditions associated with a deficiency or absence of endogenous testosterone, such as hypogonadism, gender dysphoria, and certain types of breast cancer. This gel is dispensed through a pump mechanism, which ensures easy and precise dosing. The transdermal delivery system allows for the testosterone to be absorbed directly through the skin, providing a targeted approach to therapy. The gel-like consistency of the formulation ensures a comfortable application experience for the patient.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Testosterone
Topical Gel
65d7a33a5f6e14b4aa016ec3
Service area

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Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Testosterone 25 mg/ml Transdermal Gel is a specially compounded medication designed to deliver a controlled dose of testosterone through the skin. This semisolid formulation is dispensed through a pump mechanism, which ensures that patients can apply a consistent and precise amount of medication with each use. The gel is designed to spread easily and absorb quickly into the skin, providing a convenient and non-invasive method of testosterone replacement therapy.

Testosterone replacement therapy is primarily used to treat various conditions associated with low testosterone levels, such as hypogonadism in males, certain types of breast cancer in women, and to help mitigate the effects of delayed puberty in adolescent boys. By delivering testosterone transdermally, the gel bypasses the gastrointestinal system, reducing the potential for hepatic side effects and improving the bioavailability of the hormone. This method of delivery also allows for steady absorption, which can help in maintaining more consistent blood levels of testosterone, potentially reducing the peaks and troughs associated with other delivery methods.

For patients, it is important to understand that the use of this gel should be in accordance with a healthcare provider's instructions. The area of application should be clean, dry, and free of any skin irritations. Hands should be washed thoroughly after application to prevent accidental transfer of testosterone to others. Patients should also be aware of potential side effects, which may include skin irritation at the application site, changes in libido, hair growth, and mood alterations. Regular monitoring by a healthcare provider is necessary to ensure appropriate testosterone levels are maintained and to adjust the dose if necessary.

Prescribers considering this formulation for their patients should be aware of the benefits of transdermal delivery, particularly for those who may have contraindications for oral or injectable testosterone. It is also crucial to tailor the therapy to the individual patient's needs, monitoring their response to treatment and adjusting the dose accordingly. Prescribers should also counsel patients on the proper use of the gel and the importance of adhering to application guidelines to maximize the therapeutic effects and minimize the risk of side effects or cross-contamination to others.

If you have any questions or require further information about Testosterone 25 mg/ml Transdermal Gel, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to both patients and healthcare providers to ensure the safe and appropriate use of compounded medications.

Drug Interactions

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Testosterone transdermal gel is a hormone replacement therapy used to treat conditions associated with a deficiency or absence of endogenous testosterone, such as hypogonadism in males. When considering the use of testosterone 25 mg/ml transdermal gel, it is important to be aware of potential drug interactions that may affect the efficacy of the treatment or increase the risk of adverse effects.

One significant interaction is with blood thinners, such as warfarin. Testosterone can enhance the anticoagulant effects of warfarin, potentially increasing the risk of bleeding. Patients on warfarin should have their blood clotting times or INR monitored closely, especially when starting or stopping testosterone therapy. Adjustments to the dosage of the anticoagulant may be necessary.

Testosterone may also interact with diabetic medications. It can decrease blood glucose levels, necessitating a closer monitoring of blood sugar and potential adjustments to insulin or oral diabetic medication dosages to prevent hypoglycemia.

Corticosteroids or adrenocorticotropic hormone can be affected by testosterone therapy, as testosterone may increase the risk of edema, particularly in patients with underlying cardiac, renal, or hepatic diseases. Caution is advised when testosterone is used in combination with these agents, and patients should be monitored for signs of edema.

Enzyme-inducing agents, such as certain anticonvulsants (like phenytoin) and barbiturates, can increase the clearance of testosterone, potentially leading to a decrease in its therapeutic effects. Conversely, enzyme inhibitors like certain antifungals (e.g., ketoconazole) and antibiotics (e.g., erythromycin) may increase testosterone levels, raising the risk of developing side effects.

Patients using thyroid hormone replacement therapy should be aware that testosterone can alter thyroid function tests, necessitating a reevaluation of thyroid hormone dosages.

Additionally, the use of testosterone with other androgens or anabolic steroids can potentiate the effects and side effects of testosterone, and such combinations should generally be avoided.

It is also important to note that the application site of the testosterone gel should not be exposed to high heat or covered with occlusive dressings, as this can increase testosterone absorption, potentially leading to excessive systemic exposure.

Alcohol-based products applied to the skin can also alter the absorption of testosterone gel. Patients should avoid using lotions, creams, or other topical products containing alcohol on the areas where the testosterone gel is applied.

Given the potential for drug interactions, it is crucial for patients to inform their healthcare providers of all medications, supplements, and over-the-counter products they are currently using before starting treatment with testosterone transdermal gel. Prescribers should review the patient's medication profile for potential drug interactions to ensure safe and appropriate use of testosterone therapy.

If you have any questions or require further information regarding drug interactions with testosterone 25 mg/ml transdermal gel, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the support and guidance needed to manage your treatment safely and effectively.

How Does it Work

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The Testosterone 25 mg/ml Transdermal Gel is a hormone replacement therapy designed to deliver testosterone, the primary male sex hormone, through the skin directly into the bloodstream. This semisolid formulation is specifically compounded to be dispensed through a pump mechanism, which ensures that a controlled and precise dose of testosterone is administered with each pump. The gel is applied topically, which allows for a steady absorption of the hormone over time, mimicking the body's natural rhythms of testosterone release.

Upon application to the skin, the testosterone in the gel permeates the stratum corneum, the outermost layer of the epidermis, through a process known as passive diffusion. The hormone then travels through the various layers of the skin until it reaches the blood vessels, where it is absorbed into the bloodstream. The transdermal delivery system is advantageous because it bypasses the gastrointestinal tract and liver, reducing the potential for metabolic breakdown of the hormone and avoiding first-pass metabolism, which can occur with oral formulations.

This transdermal gel is used to treat conditions associated with a deficiency or absence of endogenous testosterone, such as hypogonadism in males. By restoring testosterone levels to a normal range, the gel can alleviate symptoms associated with low testosterone, including decreased libido, fatigue, reduced muscle mass, and bone density, as well as mood disturbances. The gel may also be used in gender-affirming hormone therapy for transgender men, providing the necessary testosterone to induce and maintain secondary male sex characteristics.

It is important for both patients and prescribers to understand that the effectiveness of the Testosterone 25 mg/ml Transdermal Gel depends on proper application and adherence to dosing instructions. The site of application should be clean, dry, and free of any skin irritations or barriers that could affect absorption. Patients are advised to apply the gel at the same time each day to maintain consistent testosterone levels. Additionally, precautions should be taken to prevent transference of the gel to others, particularly women and children, as accidental exposure can lead to adverse effects.

For further information or if you have any questions regarding the Testosterone 25 mg/ml Transdermal Gel, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to ensure the safe and appropriate use of this formulation.

Frequently Asked Questions

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What is Testosterone 25 mg/ml Transdermal Gel?

Testosterone 25 mg/ml Transdermal Gel is a hormone replacement therapy used to treat symptoms associated with low testosterone levels in males. The medication is in a gel form for transdermal (through the skin) delivery of testosterone.

How should I use the Testosterone Transdermal Gel?

Apply the gel according to your doctor's prescription, typically once a day. It should be applied to clean, dry skin on areas such as the shoulders, upper arms, or abdomen. Do not apply the gel to the genitals or damaged skin.

What is the purpose of the pump mechanism in the medication's dispensing?

The pump is designed to provide a measured dose of gel, ensuring precise and consistent application. This helps in maintaining steady levels of testosterone when used regularly as prescribed.

How can I ensure I receive the correct dose of gel?

Use the pump to dispense the gel as instructed by your healthcare provider. Press the pump completely down once or more to deliver the prescribed amount of gel for your dose. Always follow the prescribed dosage and do not adjust the dose without consulting your doctor.

Can I apply the gel at any time of the day?

It is recommended to apply the gel at the same time each day, typically in the morning, to mimic the body's natural testosterone rhythms. However, follow your doctor's instructions regarding the timing of application.

How long does it take for the gel to dry, and what should I do after applying it?

The gel should dry within a few minutes. After application, allow the gel to dry completely before dressing. Wash your hands immediately with soap and water to prevent spreading the gel to others.

What should I avoid while using the Testosterone Transdermal Gel?

Avoid swimming, bathing, or showering for a certain period after applying the gel, as this can affect the absorption of testosterone. Avoid contact with pregnant women and children, and cover application sites with clothing once the gel has dried.

Can the Testosterone Transdermal Gel transfer to other people?

Yes, testosterone gel can transfer to others through skin contact with the application site. To reduce the risk of transfer, cover the area after the gel has dried and wash your hands thoroughly.

What side effects may occur with the use of this gel?

Possible side effects include skin irritation at the application site, increased red blood cell count, changes in cholesterol levels, and increased risk of prostate issues. Report any concerning symptoms to your doctor immediately.

How should I store the Testosterone Transdermal Gel?

Store the gel at room temperature away from heat and direct sunlight. Keep the container tightly closed and out of reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it's almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not use extra gel to make up for a missed dose.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Testosterone 25 mg/ml Transdermal Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Once daily