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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Prepared to a prescriber's order for one patient. Not FDA-approved.
Tetracycline is a broad-spectrum tetracycline-class antibiotic that compounding pharmacies prepare as oral suspensions, mouth rinses, topical preparations and capsules by prescription.
Tetracycline hydrochloride is the original member of the tetracycline antibiotic class. It is bacteriostatic: it binds the 30S subunit of the bacterial ribosome and stops bacteria from making proteins, so they cannot grow and multiply. Manufactured products include tetracycline hydrochloride capsules from several generic manufacturers and Pylera, a combination capsule with bismuth subcitrate potassium and metronidazole. Tetracycline capsules are FDA-approved for a long list of infections caused by susceptible organisms, including rickettsial infections such as Rocky Mountain spotted fever, chlamydial infections, respiratory, skin and urinary tract infections, and as adjunctive therapy in severe acne and intestinal amebiasis. A prescriber may order tetracycline compounded when a patient needs an oral liquid, a mouth rinse, a topical form, or a strength that is not manufactured. Compounded tetracycline preparations are not FDA-approved and require a prescription.
Tetracycline hydrochloride capsules carry no boxed warning (Pylera carries one that relates to its metronidazole component), but two class warnings matter for every patient. Used during tooth development (pregnancy, infancy and childhood to age 8) it can cause permanent yellow-gray-brown tooth discoloration and enamel defects, so it is generally avoided in children under 8. It crosses the placenta and can affect fetal bone development; the label says not to use it in pregnancy unless absolutely necessary. Other warnings: exaggerated sunburn, intracranial hypertension with headache and vision changes, and Clostridioides difficile diarrhea; the label also reports esophageal ulceration when capsules are taken with too little water. People allergic to any tetracycline should not take it. Antacids, iron, zinc, calcium, dairy and bicarbonate reduce absorption; tetracycline can increase the effect of blood thinners, make hormonal birth control less reliable, and should not be combined with penicillin or isotretinoin. Milk levels are low and short courses are considered acceptable while breastfeeding, though the manufacturer advises against it. Common side effects are nausea, vomiting and diarrhea. For severe headache, blurred vision, watery or bloody diarrhea, or a rash, talk to your prescriber or pharmacist.
Tetracycline inhibits bacterial protein synthesis by binding the 30S ribosomal subunit and blocking aminoacyl-tRNA attachment; it is primarily bacteriostatic. Oral absorption occurs in the stomach and proximal small intestine and is reduced by chelation with aluminum, calcium, magnesium and iron; the drug is bound to plasma protein in varying degrees, distributes well into most tissues and fluids with poor CSF penetration, and is eliminated primarily renally, so renal impairment raises serum levels and can produce azotemia, hyperphosphatemia and acidosis through antianabolic effects. Labeled indications (tetracycline hydrochloride capsules) include rickettsiae, Mycoplasma pneumoniae, Chlamydia, relapsing fever, tularemia, plague, cholera, brucellosis, susceptible respiratory, skin and urinary infections, adjunctive therapy in severe acne and intestinal amebiasis, and penicillin alternatives such as syphilis, anthrax and Listeria. Pylera is labeled for Helicobacter pylori eradication with omeprazole. Prescribers have ordered compounded tetracycline for periodontitis and Helicobacter pylori regimens, which StatPearls lists as off-label uses. Dosing is per prescriber. Periodic hematologic, renal and hepatic monitoring is advised for long-term therapy. Tetracycline is not a controlled substance.
Shake the bottle if your label says to. Measure each dose with the oral syringe or dosing cup the pharmacy gave you, never a kitchen spoon. Give the liquid slowly into the mouth. Rinse the syringe with water after each use. Call the pharmacy if you are unsure how to measure.
Storage depends on the vehicle. Water-based liquids with a preservative usually carry a USP <795> beyond-use date of up to 35 days; without a preservative they are kept refrigerated for up to 14 days. Oil-based (nonaqueous) oral liquids may carry up to 90 days. Your label states whether to refrigerate and the beyond-use date. Keep out of reach of children and discard after that date.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Take orally
